Atypical Breast Proliferative Lesions and Benign Breast Disease 1st ed. 2018 Edition

Atypical Breast Proliferative Lesions and Benign Breast Disease 1st ed. 2018 Edition

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Management of atypical breast lesions continues to evolve. There is considerable controversy as to whether these entities represent risk factors for future breast cancer or whether they are instead precursor lesions.  A better understanding of the prognostic and therapeutic implications of each of these lesions is important for assessing subsequent breast cancer risk.  Risk assessment tools are available for screening high risk patients and understanding the utility and limitations of these tools is important for all clinicians involved in the care of patients. There have been significant advances in breast cancer screening in the last several year including breast tomosynthesis, automated breast ultrasound, molecular imaging, as well as accelerated breast MRI protocols. This has raised the question: Do women at risk for breast cancer need additional breast cancer screening using these newer imaging modalities?  In addition, with these advances in imaging, can women with atypical proliferative lesions be observed rather than undergoing surgical excision as some suggest? The role of observation, surgical excision and even prophylactic mastectomy in women with atypical proliferative lesions continues to be debated; however there is data that can guide physicians in the management of these patients.  Pleomorphic Lobular carcinoma in-situ (PLCIS) is a distinct pathological entity within LCIS and there is no consensus regarding surgical margins or the need for adjuvant treatment to prevent recurrence.  Recently, ductal carcinoma in-situ (DCIS) has been the subject of much controversy: is it truly a cancer or is it instead a precursor lesion.  The traditional management of DCIS with lumpectomy and radiation is now being debated and recent data demonstrates that low grade DCIS can be managed with observation.  Clinical trials are now accruing patients with low and intermediate grade DCIS to observation and close surveillance, and not surgical excision.  Finally, new guidelines for chemoprevention with the use of tamoxifen and raloxifen for women with atypical proliferative lesions, LCIS, PLCIS, and DCIS are available and should be discussed as an option when guiding management of these patients.

This book will provide a comprehensive review of this field and will serve as a valuable resource for clinicians, general surgeons, breast surgeons and surgical oncologists, as well as researchers with an interest in the management of atypical breast lesions. The book will review new data about breast cancer, risk factors for breast cancer, pathological features unique to each entity, the characteristic findings on imaging, risk stratification for genetic testing, as well as the current evidence-based management of each of these breast lesions. Our text will provide assessment tools for risk prediction of breast cancer. We will provide data on the current imaging modalities, as well as advanced screening options available for diagnosis and following these patients.  Current management of many of these lesions continues to be controversial in regard to observation with close surveillance versus the need for surgical excision of these lesions based on future risk or whether these lesions are precursor lesion.  For ductal carcinoma in-situ, the debate continues in regards to whether this disease entity is a precursor lesion that can be managed with observation or hormonal therapy, or is DCIS cancer and treated with lumpectomy and radiation.  Several studies have been published where patients are managed with observation and treatment with hormonal therapy before surgical management. New trials have already begun accruing patients with low to intermediate grade DCIS where patients will be managed with observation versus hormonal therapy only.  Management of DCIS continues to evolve and current management will be discussed

This text will provide a concise but comprehensive summary of the current management of patients with atypical breast proliferative lesions and some benign breast lesions and will help guided management of these patients.  All chapters in this text will be written by experts in the field in each of these disease entities.  They will all include the most up to date research and clinical information to enhance our understanding and treatment of patients.

COMPREHENSIVE ABSITE REVIEW QUESTIONS (ABSITE 2015)

COMPREHENSIVE ABSITE REVIEW QUESTIONS (ABSITE 2015)

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Do you want to get above 90th percentile on the ABSITE 2015 exam? Do you want to focus your studying on high yield ABSITE topics? Do you want a review book that also contains multiple choice questions? If so, this book is for you. This book captures all of the high yield absite topics in over 1100 pages of review. To make reviewing specific topics easier for you, all of the topics are hyperlinked from the table of contents

Encyclopedia of Public Health [2 volumes]: Principles, People, and Programs 1st Edition

Encyclopedia of Public Health [2 volumes]: Principles, People, and Programs 1st Edition

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Providing context to today’s public health practices and broad coverage of topics, this book demonstrates how cross-disciplinary studies are critical to addressing current health issues.

• Presents complex health issues in ways that encourage readers to pursue the many different opportunities in the field of public health

• Supplies insights from contributors that include experts on diseases such as hepatitis, substance abuse prevention, the history of medicine, and neurology

• Provides a functional foundation for those working to improve the health of communities or individuals

• Identifies relevant connections between physical, social, and emotional health and well-being to everyday life

• Serves as a gateway to additional research and study by providing suggested further readings with each entry

Ear Acupuncture: A Precise Pocket Atlas, Based on the Works of Nogier/Bahr (Complementary Medicine (Thieme Paperback)) 2nd edition Edition

Ear Acupuncture: A Precise Pocket Atlas, Based on the Works of Nogier/Bahr (Complementary Medicine (Thieme Paperback)) 2nd edition Edition

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Written by one of the world’s leading experts on Western auriculotherapy, Ear Acupuncture — now in a fully updated Second Edition — provides readers with succinct descriptions of acupuncture points and practical advice on how to incorporate ear acupuncture treatment strategies and techniques into daily practice.

Based on the work of auriculotherapy masters Nogier and Bahr, each practical two-page unit is comprised of concise text on the left-hand side supplemented by clearly labeled line drawings on the right. Localization points indicated in color depict each specific reflex zone. In cases where localization is particularly difficult, helpful enlargements of the region in question allow for easy identification.

 

Features

 

 

  • 360 high-quality drawings demonstrate key points and treatment options
  • Detailed coverage of nine new points, including the anger point, shen men point, super omega point, and more
  • Numerous cross-referenced indications tables allow quick access to needed information

 

This user-friendly guide is the ideal choice for students or teachers of acupuncture and pain management or for anyone involved in the practice of complementary medicine.

Rho GTPases: Molecular Biology in Health and Disease

Rho GTPases: Molecular Biology in Health and Disease

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Rho GTPases control many aspects of cell physiology. This includes polarity, endo/exocytosis, adhesion, motility, transcriptional activation, cell cycle progression or apoptosis. In view of such pleiotropic activities, Rho-controlled signaling has proven to be of medical relevance, especially in tumorigenesis, disease-associated bone remodeling and infectiology.

This book is divided into three parts. Part 1 gives an evolutionary perspective of the Rho family, its atypical members, and an overview of how Rho activity is regulated. Part 2 addresses two important aspects of multicellularity controlled by Rho-dependent pathways, namely, cell-cell interactions and mechanotransduction. It also describes how post-translational modifications control Rho activity and how this is exploited by pathogenic bacteria. Part 3 explores several examples of the variety of pathophysiological processes controlled by Rho signaling, and gives a successful example of translational research, from the inhibition of Rho activation to the development of new molecules against osteoporosis.

This updated review on the biology of Rho GTPases is an essential read for molecular and cell biologists. It is also an invaluable guide to post-graduate and medical students who wish to deepen their knowledge in cell biology.

Gerontorheumatology 1st ed

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Gerontorheumatology 1st ed

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This book covers all aspects of the specialized field of gerontorheumatology, providing a complete overview of rheumatic and musculoskeletal diseases and related conditions in the elderly. The emphasis is particularly on pathogenesis, diagnosis, prevention, and treatment, including the latest advances in biological and pharmacological therapy and potential treatment side effects. The book will provide the reader with a keen awareness of the characteristic features, distinctive etiologies, and different courses of the various disorders of the musculoskeletal system in the geriatric population. Diagnostic and treatment considerations of special relevance in daily practice are highlighted, and the importance of comorbidities and their rheumatic consequences is also emphasized. The book will be of value for gerontologists, rheumatologists, internists, and rehabilitation physicians and will offer excellent guidance for general practitioners, who are typically the first to deal with disorders of the musculoskeletal system in elderly patients.

Medicine in the Qur’an and Sunnah. An Intellectual Reappraisal of the Legacy and Future of Islamic Medicine and its Represent

Medicine in the Qur’an and Sunnah. An Intellectual Reappraisal of the Legacy and Future of Islamic Medicine and its Represent

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It is the aim of this book while clarifying doubts and misconceptions, to provide a thorough reappraisal of the intellectual and rich cultural heritage of Islam with regards to the principles and practice of medicine and its representation to the world in the language of today. In nine chapters a range of topics are discussed including: The Promotion of Medical Education and Health Services; Personal and Environmental Hygiene; Circumcision; Manners of Eating; Social and Mental Heath; Curative Medicine; The Provision of Adequate and Potable Water; Magic, Witchcraft, Enchantments and Charms; Euthanasia; Suicide; The Rehabilitation of the Sick and the Needy; The Source of Human Creation; Sex Differentiation and Determination; Healing through Miracles; Magic and Soothsaying; HIV Infection and AIDS; Abortion; Females in Medical Practice; and The Challenges of Modem Medicine to Muslims.

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