Oncologic Emergency Medicine: Principles and Practice 1st ed

This is the first comprehensive clinical reference on cancer emergencies. It is edited and written by world-renowned experts in emergency medicine and oncology and covers the diagnosis and management of the full range of emergencies caused directly by cancer or by its treatment. It shows how the entire spectrum of clinical medicine is brought to bear in the care of cancer patients in the unique setting of the emergency department (ED), from health promotion and prevention, to treatment and palliative care. Recognizing the multiple, overlapping contexts in which emergency care of cancer patients occurs, the book addresses clinically crucial interdisciplinary topics such as the ethics of ED cancer care, the interface with palliative social work, substance abuse, and more. Finally, perspective on care system and social forces that shape ED cancer care, such as cancer care disparities and care models, and on how ED cancer care is delivered outside of the United States, frame the book as a whole. Against the backdrop of rising numbers of cancer patients and survivors as the United States population ages and a forecast shortage of oncologists, this book is designed to serve as the authoritative, single-source clinical reference on cancer emergencies. The intended audience includes emergency physicians, oncologists, internists, family physicians, emergency nurses, nurse practitioners, physician assistants, policy makers as well as pre- and postgraduate trainees.

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Geriatric Psycho-Oncology: A Quick Reference on the Psychosocial Dimensions of Cancer Symptom Management (APOS Clinical Reference Handbooks) 1st Edition

Geriatric Psycho-Oncology is a comprehensive handbook that provides best practice models for the management of psychological, cognitive, and social outcomes of older adults living with cancer and their families. Chapters cover a wide range of topics including screening tools and interventions, psychiatric emergencies and disorders, physical symptom management, communication issues, and issues specific to common cancer sites. A resource section is appended to provide information on national services and programs. This book features contributions from experts designed to help clinicians review, anticipate and respond to emotional issues that often arise in the context of treating older cancer patients. Numerous cross-references and succinct tables and figures make this concise reference easy to use. Geriatric Psycho-Oncology is an ideal resource for helping oncologists and nurses recognize when it may be best to refer patients to their mental health colleagues and for those who are establishing or adding psychosocial components to existing clinics.

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Anticancer Therapeutics: From Drug Discovery to Clinical Applications 1st Edition

An integrated presentation of the basic science and clinical applications of anticancer agents

Aimed at both undergraduate and postgraduate readers, this unique text provides readers with a fully-integrated presentation of all aspects of the science of anticancer drugs, including their chemistry, pharmacology, and clinical applications.

After heart disease, cancer is the number one killer worldwide, and the tumor microenvironment is forever changing, creating an ever-greater demand for safer, more effective anticancer agents. In response to that demand, the $100 billion cancer drug market continues to grow, with our increased understanding of cancer leading to new drugs being used clinically almost every year.

Anticancer Therapeutics is divided into three sections. Section 1 is an introduction to cancer and therapeutics, and covers the etiology and cellular and molecular basis of cancer. In Section 2, the authors focus on the anticancer agents — their discovery, synthesis, mode of action, mechanisms of resistance, and adverse reactions. Section 3 focuses on specific cancers, explaining how and why the various agents discussed in Section 2 are used, both individually and in combination, to treat different cancers.

  • Integrates aspects of basic science, including chemistry and pharmacology and clinical medicine in relation to cancer therapeutics
  • Written by an author team comprising specialists in medicinal chemistry, pharmacology, and oncology
  • Features full-color images throughout illustrating how drugs bind to cellular targets and exert their pharmacological effect
  • Divided into three sections, covering the etiology and cellular and molecular basis of cancer, anticancer agents, and drug applications for different cancers.

Providing the reader with an integrated understanding of all aspects of the science of anticancer agents, this is an ideal textbook for undergraduates studying medicine, nursing, medicinal chemistry, pharmacy, pharmacology and other allied heath / life sciences. It is also a valuable bench reference for pharmacists, medics, and pharmaceutical researchers working in both academia and industry.

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Contemporary Oral Oncology: Oral and Maxillofacial Reconstructive Surgery 1st ed

This is the third of four volumes that together offer an authoritative, in-depth reference guide covering all aspects of the management of oral cancer from a multidisciplinary perspective and on the basis of a strong scientific foundation. This volume is devoted to the reconstructive surgical techniques used in patients with oral cancer. Following introductory chapters outlining the general principles of reconstructive surgery in the oral cavity and the planning of maxillofacial reconstruction, detailed descriptions of the options and techniques employed in reconstruction of each of the functional subunits are provided. Important technologic advances are also discussed, including image-guided surgery, robotic surgery, and tissue-engineered and prefabricated approaches. Finally, the current status of facial transplantation for maxillofacial reconstruction is reviewed. This volume is intended for both trainees and practicing surgeons.

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rview on all volumes:

Volume 1: Biology, Epidemiology, Etiology, and Prevention

Volume 2: Diagnosis and Management

Volume 3: Oral and Maxillofacial Reconstructive Surgery

Volume 4: Rehabilitation and Supportive Care

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Development of Oral Cancer: Risk Factors and Prevention Strategies 1st ed

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Next Generation Point-of-care Biomedical Sensors Technologies for Cancer Diagnosis 1st ed

This book presents recent research on cancer detection methods based on nanobiosensors, which offer ultrasensitive point-of-care diagnosis.

Several methods for diagnosing cancer have been discovered and many more are currently being developed. Conventional clinical approaches to detecting cancers are based on a biopsy followed by histopathology, or on the use of biomarkers (protein levels or nucleic acid content). Biopsy is the most widely used technique; however, it is an invasive technique and is not always applicable. Furthermore, biomarker-based detection cannot be relied on when the biomarkers are present in an extremely low concentration in the body fluids and in malignant tissues.

Thus, in recent years highly sensitive and robust new cancer diagnosis techniques have been developed for clinical application, and may offer an alternative strategy for cancer diagnosis. As such, this book gathers the latest point-of-care cancer diagnostic methods and protocols based on biomedical sensors, microfluidics, and integrated systems engineering. It also discusses recent developments and diagnostics tests that can be conducted outside the laboratory in remote areas. These technologies include electrochemical sensors, paper-based microfluidics, and other kit-based diagnostic methods that can be adapted to bring cancer detection and diagnostics to more remote settings around the globe.

Overall, the book provides students, researchers, and clinicians alike a comprehensive overview of interdisciplinary approaches to cancer diagnosis.

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Oncologic Imaging: Bone Tumors 1st ed

This book aims to provide readers with a sound understanding of the spectrum of radiologic appearances of bone tumors, which reflect histopathology, and the pattern analysis of imaging findings.The first part of the book explains basic concepts and diagnostic parameters, including demographics, lesion location, biological activity, matrix mineralization, and endosteal and periosteal reactions. In the second part, typical and atypical radiologic features of bone tumors are reviewed in detail, with emphasis on the characteristic radiographic and MR imaging findings and reference to schematic drawings and pathologic or operative images when appropriate.The third part focuses on problem solving in cases encountered in real radiology practice and identifies categorical patterns on the basis of radiographic and MR variables and lesion location. Informative cases are illustrated and compared to enhance understanding of differential diagnosis using pattern analysis. The final part of the book helps readers to consolidate what they have learned and to hone their diagnostic reasoning skills by presenting about 30 typical bone tumor cases with questions, answers, and commentary.

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Hematopoietic Stem Cell Transplantation for the Pediatric Hematologist/Oncologist 1st ed. 2018 Edition

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This volume provides a comprehensive and state-of-the-art review on pediatric hematopoietic stem cell transplantation (HSCT). The book covers such topics as graft versus host disease (GVHD), HSC mobilization, stem cell selection, and HSCT-relevant laboratory assays and techniques. The text is specially formatted so that the scientific basis of HSCT and ethical considerations are integrated into the relevant clinical framework. Each chapter also includes diagrams, illustrations, and tables that summarize key points and concepts that can be used as a quick visual reference for the reader.

Written by experts in the field, Hematopoietic Stem Cell Transplantation for the Pediatric Hematologist/Oncologist is a valuable resource on pediatric HSCT suited for pediatric hematologists-oncologists, fellows, advanced practitioners, clinical nurses, and other referring physicians.

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The Cancer Degradome: Proteases and Cancer Biology

Proteases that act in the extracellular environment have been historically associated with tumorigenesis and metastasis by virtue of their ability to carry out “path-clearing” for cancer cells. In the past few years it has become clear that they also shape the pericellular signaling environment, with profound consequences for cell fate and phenotype in both normal development and disease states. The repertoire of proteases that cells and tissues coordinately regulate in order to modulate their local environment is the DEGRADOME – which in humans is represented by at least 569 proteases in five catalytic classes. “The Cancer Degradome: Proteases in Cancer Biology” , edited by Dylan Edwards, Francesco Blasi, Gunilla-Høyer-Hansen and Bonnie Sloane, covers recent knowledge of the composition of the Degradome, how it can be studied using modern approaches such as transcriptomics and mass spectrometry; how protease activity can be imaged both in vitro and in vivo; how gene knockout mice have improved our knowledge of the roles of proteases in cancer; the links that have emerged between proteolysis and cell signaling; how the Degradome can be a useful source of diagnostic and prognostic markers; and finally new approaches to target proteolysis for therapy.

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The American Cancer Society’s Principles of Oncology: Prevention to Survivorship 1st Edition

Developed by the American Cancer Society this new textbook designed for a wide range of learners and practitioners is a comprehensive reference covering the diagnosis of cancer, and a range of related issues that are key to a multidisciplinary approach to cancer and critical to cancer control and may be used in conjunction with the book, The American Cancer Society’s Oncology in Practice: Clinical Management.Edited by leading clinicians in the field and a stellar contributor list from the US and Europe, this book is written in an easy to understand style by multidisciplinary teams of medical oncologists, radiation oncologists and other specialists, reflecting day-to-day decision-making and clinical practice. Input from pathologists, surgeons, radiologists, and other specialists is included wherever relevant and comprehensive treatment guidelines are provided by expert contributors where there is no standard recognized treatment. This book is an ideal resource for anyone seeking a deeper understanding of cancer prevention, screening, and follow-up, which are central to the ACS’s worldwide mission on cancer control.

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