Reviews of Physiology, Biochemistry and Pharmacology Vol. 174

Leading researchers are specially invited to provide a complete understanding of a key topic within the multidisciplinary fields of physiology, biochemistry and pharmacology. In a form immediately useful to scientists, this periodical aims to filter, highlight and review the latest developments in these rapidly advancing fields.

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Lecture Notes Clinical Biochemistry 10th Edition

Clinical Biochemistry Lecture Notes presents the fundamental science behind common biochemical investigations used in clinical practice. Taking a system-based approach, it explores the underlying physiological rationale for tests, with each test explained within the context of disruption by disease. It also explores the value and limitations of biochemical investigations, while helping readers to quickly develop the knowledge and skills required to select the appropriate investigations for diagnosis and management, and to correctly interpret test results. Case studies throughout chapters place the information within a clinical context to further assist readers in the development of test-selection and interpretation skills.

Key features include:

  • A comprehensive, yet concise overview of the science behind common biochemical investigations
  • Helps readers rapidly acquire a fully integrated, practical understanding of biochemical diagnostics
  • Full-colour flowcharts and algorithms detailing the rationale for tests, the biochemical processes involved, and test procedures, for quick comprehension and reference
  • More clinical cases demonstrating application to practice

Now in its tenth edition, this classic introductory, reference, and revision text is indispensable to medical students, and all those who want to quickly acquire a practical understanding of the scientific principles underpinning biochemical tests and a working knowledge of test selection, test procedures, and the interpretation of results within a clinical context.

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Chromogranins: from Cell Biology to Physiology and Biomedicine (UNIPA Springer Series) 1st ed. 2017 Edition

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The volume is designed to provide an integrated overview of the results from the last fifteen years of research on Chromogranins in relation to cell biology, physiology and biomedicine. The different chapters highlight novel activities of these proteins, including their role in granule biogenesis, hormone co-storage, stimulus-processing-secretion coupling, autonomic sympathetic/parasympathetic balance, immune and cardiocirculatory function, and the response to stress. Biomedical aspects are also illustrated with focus on the prognostic and diagnostic significance of Chromogranin in the presence of tumors, cardiovascular diseases and inflammatory conditions.

The volume is of interest for laboratory and clinical scientists, PhD and Post-doc students that will be inspired to go deep inside the molecular, biochemical, physiological, pharmacological and clinical aspects of these fascinating multifaceted proteins.

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Fundamentals of Biomechanics: Equilibrium, Motion, and Deformation 4th ed. 2017 Edition

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This textbook integrates the classic fields of mechanics―statics, dynamics, and strength of materials―using examples from biology and medicine. The book is excellent for teaching either undergraduates in biomedical engineering programs or health care professionals studying biomechanics at the graduate level. Extensively revised from a successful third edition, Fundamentals of Biomechanics features a wealth of clear illustrations, numerous worked examples, and many problem sets. The book provides the quantitative perspective missing from more descriptive texts, without requiring an advanced background in mathematics. It will be welcomed for use in courses such as biomechanics and orthopedics, rehabilitation and industrial engineering, and occupational or sports medicine.

This book:

  • Introduces the fundamental concepts, principles, and methods that must be understood to begin the study of biomechanics
  • Reinforces basic principles of biomechanics with repetitive exercises in class and homework assignments given throughout the textbook
  • Includes over 100 new problem sets with solutions and illustrations

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Clinical Biochemistry:Metabolic and Clinical Aspects: With Expert Consult access, 3e 3rd Edition

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Now fully revised and updated, Clinical Biochemistry, third edition is essential reading for specialty trainees, particularly those preparing for postgraduate examinations. It is also an invaluable current reference for all established practitioners, including both medical and scientist clinical biochemists.

Building on the success of previous editions, this leading textbook primarily focuses on clinical aspects of the subject, giving detailed coverage of all conditions where clinical biochemistry is used in diagnosis and management – including nutritional disorders, diabetes, inherited metabolic disease, metabolic bone disease, renal calculi and dyslipidaemias. The acquisition and interpretation of clinical biochemical data are also discussed in detail.

  • Expanded sections on haematology and immunology for clinical biochemists provide a thorough understanding of both laboratory and clinical aspects
  • New chapters are included on important evolving areas such as the metabolic response to stress, forensic aspects of clinical biochemistry and data quality management
  • An extended editorial team – including three expert new additions – ensures accuracy of information and relevance to current curricula and clinical practice
  • A superb new accompanying electronic version provides an enhanced learning experience and rapid reference anytime, anywhere!

Elsevier ExpertConsult.com

Enhanced eBooks for medical professionals

Compatible with PC, Mac®, most mobile devices and eReaders, browse, search, and interact with this title – online and offline. Redeem your PIN at expertconsult.com today!

  • Straightforward navigation and search across all Elsevier titles
  • Seamless, real-time integration between devices
  • Adjustable text size and brightness
  • Notes and highlights sharing with other users through social media
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Medical Biochemistry – An Illustrated Review (Thieme Illustrated Reviews) 1 Pap/Psc Edition

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From the Back Cover

Highly rated by “First Aid for the USMLE” !

“An excellent textbook, highly illustrated with biochemical pathways and physiological explanations as well as clinical applications. The book contains many review questions and answers and provides an access code for further information. Recommended for medical students.– Pediatric Endocrinology ”

“Medical Biochemistry – An Illustrated Review” – for success in the classroom and on the USMLE! High-yield, biochemical principles presented in a concise, easy-to-understand format with supporting summary tables 200+ full-color illustrations of biochemical pathways that highlight associated disorders and drug targets 400+ color-coded boxes that connect biochemical concepts with other basic sciences and clinical conditions 400 factual and USMLE-style questions with full explanations online

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Handbook of Blood Gas/Acid-Base Interpretation 2nd ed

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Handbook of Blood Gas/Acid-Base Interpretation, 2nd edition, simplifies concepts in blood gas/acid base interpretation and explains in an algorithmic fashion the physiological processes for managing respiratory and metabolic disorders. With this handbook, medical students, residents, nurses, and practitioners of respiratory and intensive care will find it possible to quickly grasp the principles underlying respiratory and acid-base physiology, and apply them. Uniquely set out in the form of flow-diagrams/algorithms charts, this handbook introduces concepts in a logically organized sequence and gradually builds upon them. The treatment of the subject in this format, describing processes in logical steps makes it easy for the reader to cover a difficult- and sometimes dreaded- subject rapidly.

From the Back Cover

Analysis of blood gas can be a daunting task. However, it is still one of the most useful laboratory tests in managing respiratory and metabolic disorders. Busy medical students have struggled ineffectively with Hasselbach’s modification of the Henderson equation, been torn between the Copenhagen and the Boston schools of thought; and lately, been confronted with the radically different strong-ion approach.

In modern medical practice, the health provider’s time is precious: it is crucial to retain focus on those aspects of clinical medicine that are of key importance. Adoption of an algorithm-based approach in the study of topics that are hard to understand (particularly those that are rooted in clinical physiology) can be extremely advantageous. Handbook of Blood Gas/Acid-Base Interpretation, 2nd edition, is organized in a logical sequence of flow charts that introduce concepts and gradually build upon them. This approach facilitates understanding and retention of the subject matter. Medical students, residents, nurses, and practitioners of respiratory and intensive care will find it possible to quickly grasp the principles underlying respiratory and acid-base physiology, and apply them effectively in clinical decision making.

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Enzyme Inhibition in Drug Discovery and Development: The Good and the Bad 1st Edition

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The science and applied approaches of enzyme inhibition in drug discovery and development

Offering a unique approach that includes both the pharmacologic and pharmaco-kinetic aspects of enzyme inhibition, Enzyme Inhibition in Drug Discovery and Development examines the scientific concepts and experimental approaches related to enzyme inhibition as applied in drug discovery and drug development.

With chapters written by over fifty leading experts in their fields, Enzyme Inhibition in Drug Discovery and Development fosters a cross-fertilization of pharmacology, drug metabolism, pharmacokinetics, and toxicology by understanding the “good” inhibitions—desirable pharmacological effects—and “bad” inhibitions—drug–drug interactions and toxicity. The book discusses:

  • The drug discovery process, including drug discovery strategy, medicinal chemistry, analytical chemistry, drug metabolism, pharmacokinetics, and safety biomarker assessment
  • The manipulations of drug metabolizing enzymes and transporters as well as the negative consequences, such as drug–drug interactions
  • The inhibition of several major drug target pathways, such as the GPCR pathway, the NFkB pathway, and the ion channel pathway

Through this focused, single-source reference on the fundamentals of drug discovery and development, researchers in drug metabolism and pharmacokinetics (DMPK) will learn and appreciate target biology in drug discovery; discovery biologists and medicinal chemists will also broaden their understanding of DMPK.

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Case Files: Biochemistry, 2nd Edition 2nd Edition

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Fifty clinical cases help you excel in biochemistry courses and the USMLE Step 1

Case Files: Biochemistry: Second Edition presents 50 clinical cases with open-ended questions which weave basic science concepts into the clinical scenario. Each case includes an extended discussion (including definitions and a pathophysiology discussion), key points, and 3-5 USMLE-style comprehension questions. The authors are experienced teachers from the University of Texas-Houston Medical School in Houston, Texas.

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