Resistance to Tyrosine Kinase Inhibitors (Resistance to Targeted Anti-Cancer Therapeutics) 1st ed

About the Author

Imaging and Intervention in Urinary Tract Infections and Urosepsis 1st ed. 2018 Edition

Aimed at practicing clinicians and radiologists, this volume provides up-to-date, detailed information on potentially severe urinary tract infections (UTIs), which frequently require intensive in-patient antibiotic therapy, percutaneous or surgical treatment. UTIs are the most prevalent infectious illness, and account for hundreds of thousands of emergency and hospital admissions yearly. Furthermore, UTIs are the most common (almost 40%) type of hospital-acquired infections, with bladder catheterisation being the key risk factor. According to the European Association of Urology guidelines, complicated urinary tract infections (C-UTIs) are those associated with structural or functional genitourinary abnormalities or with conditions that impair the host’s defence mechanisms, leading to an increased risk of acquiring infection or therapy failure.

Besides offering current perspectives from urologists, nephrologists, and specialists in infectious diseases, the book presents the techniques and highlights the role of ultrasound and contrast-enhanced ultrasound, nuclear medicine, multidetector computed tomography (CT) and magnetic resonance imaging (MRI) in providing comprehensive investigations of upper and lower tract UTIs, and of systemic infections from unknown sources. Cross-sectional imaging is currently recommended to confirm UTI, to assess severity and look for underlying treatable structural or functional abnormalities, in order to provide a consistent basis for a correct therapeutic choice.

Furthermore, dedicated chapters illustrate the current status of UTI imaging in children and the expanding role and possibilities of interventional radiology in the treatment of severe urinary tract infections.

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Philosophy of Medicine: An Introduction 1st Edition

What kind of knowledge is medical knowledge? Can medicine be explained scientifically? Is disease a scientific concept, or do explanations of disease depend on values? What is “evidence-based” medicine? Are advances in neuroscience bringing us closer to a scientific understanding of the mind?

The nature of medicine raises fundamental questions about explanation, causation, knowledge and ontology – questions that are central to philosophy as well as medicine. This book introduces the fundamental issues in philosophy of medicine for those coming to the subject for the first time, including:

• understanding the physician–patient relationship: the phenomenology of the medical encounter.

• Models and theories in biology and medicine: what role do theories play in medicine? Are they similar to scientific theories?

• Randomised controlled trials: can scientific experiments be replicated in clinical medicine? What are the philosophical criticisms levelled at RCTs?

• The concept of evidence in medical research: what do we mean by “evidence-based medicine”? Should all medicine be based on evidence?

• Causation in medicine.

• What do advances in neuroscience reveal about the relationship between mind and body?

• Defining health and disease: are explanations of disease objective or do they depend on values?

• Evolutionary medicine: what is the role of evolutionary biology in understanding medicine? Is it relevant?

Extensive use of empirical examples and case studies are included throughout, including debates about smoking and cancer, the use of placebos in randomised controlled trials, controversies about PSA testing and research into the causes of HIV. This is an indispensable introduction to those teaching philosophy of medicine and philosophy of science.

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Atlas of Neurosurgical Techniques: Spine and Peripheral Nerves 2nd Edition

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From the Back Cover

Penetrating Trauma: A Practical Guide on Operative Technique and Peri-Operative Management 2nd ed. 2017 Edition

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From the Back Cover

Heart and Coronary Arteries: An Anatomical Atlas for Clinical Diagnosis, Radiological Investigation, and Surgical Treatment

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The magnificent anatomic presentation in this book “The Heart and Cor­ onary Arteries” has a unique importance for surgeons. It is a fundamental contribution to the anatomy of the heart and great arteries as well, because of the analytical, detailed, and imaginative anatomic approach of the author. While surgery from time to time is influenced by the development of new physiologic principles and techniques, methods of intra- and post-operative support, and new diagnostic methodology, the excellence of its results con­ tinues to be related primarily to the precision and perfection of the opera­ tive procedure itself. The operative procedure can be precise and perfect only if it is based upon the surgeon’s profound knowledge of normal anatomy, his understanding of the alterations in this normal anatomy by the pathol­ ogy with which he is dealing, and his ability to use this anatomic informa­ tion in organizing and effecting his surgical procedure. The cardiac sur­ geon, therefore, will find great rewards from intense study of this anatomic atlas. The cardiologist, the pediatric cardiologist, the anatomist, the pathol­ ogist, and students interested in cardiac disease will benefit to almost the same degree from a careful study of this work. May 1975 JOHN W. KIRKLIN, M. D.

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PET/CT in Prostate Cancer (Clinicians’ Guides to Radionuclide Hybrid Imaging) 1st ed. 2017 Edition

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This pocket book explains the significant and well-documented impact that PET/CT can have on the management of prostate cancer through the provision of high-quality evidence regarding function and structure. Up-to-date information is supplied on the relevance of PET/CT to diagnosis, treatment planning, and therapy, including the emerging role of PET/CT with PSMA. Readers will also find clear explanation of the relation of the clinical and pathological background to imaging and the value of PET/CT compared with conventional radiological imaging. The book will be an excellent asset for referring clinicians, nuclear medicine/radiology physicians, radiographers/technologists, and nurses who routinely work in nuclear medicine and participate in multidisciplinary meetings. It is published within the Springer series Clinicians’ Guides to Radionuclide Hybrid Imaging, which presents contributions from professionals worldwide who share a common purpose in promoting nuclear medicine as an important imaging specialty for the diagnosis and management of oncological and non-oncological conditions.

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Advances in Laparoscopy of the Abdominal Wall Hernia

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From the Back Cover

Key Concepts and Issues in Nursing Ethics 1st ed. 2017 Edition

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Short case studies, based on real stories from the health care arena, ensure that each chapter of this book is rooted in descriptions of nursing practise that are grounded, salient narratives of nursing care. The reader is assisted to explore the ethical dimension of nursing practice: what it is and how it can be portrayed, discussed, and analysed within a variety of practice and theoretical contexts. One of the unique contributions of this book is to consider nursing not only in the context of the individual nurse – patient relationship but also as a social good that is of necessity limited, due to the ultimate limits on the nursing and health care resource. This book will help the reader consider what good nursing looks like, both within the context of limitations on resources and under conditions of scarcity.

Indeed, any discussion of ethical issues in nursing should be well grounded in a conceptualisation of nursing that nursing students and practising nursing can recognise, accept and engage with. Nursing, like medicine, social work and teaching has a clear moral aim – to do good. In the case of nursing to do good for the patient. However it is vital that in the pressurised, constrained health service of the 21st century, we help nurses explore what this might mean for nursing practice and what can reasonably be expected of the individual nurse in terms of good nursing care.

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