Curbside Consultation in GI Cancer for the Gastroenterologist: 49 Clinical Questions (Curbside Consultation in Gastroenterology)

Curbside Consultation in GI Cancer for the Gastroenterologist: 49 Clinical Questions (Curbside Consultation in Gastroenterology)

Are you looking for concise, practical answers to questions that are often left unanswered by traditional cancer references that are not designed for gastroenterologists? Are you seeking brief, evidence-based advice for complicated cases or patients with complications that need management? Curbside Consultation in GI Cancer for the Gastroenterologist: 49 Clinical Questions provides quick and direct answers to the thorny questions commonly posed during a “curbside consultation” between colleagues.

Dr. Douglas G. Adler has designed this unique reference, which offers expert advice, preferences, and opinions on tough clinical questions commonly associated with GI cancer. The unique Q&A format provides quick access to current information related to GI cancer with the simplicity of a conversation between two colleagues. Numerous images, diagrams, and references are included to enhance the text and to illustrate the treatment of GI cancer patients.

Curbside Consultation in GI Cancer for the Gastroenterologist: 49 Clinical Questions provides information basic enough for residents while also incorporating expert advice that even high-volume clinicians will appreciate. Gastroenterologists, fellows and residents in training, surgical attendings, and surgical residents will benefit from the user-friendly and casual format and the expert advice contained within.

Some of the questions that are answered:
• An 81-year-old man is found to have unresectable esophageal cancer and malignant dysphagia. Should he have a stent? A nasogastric feeding tube? A PEG tube?
• How is tumor-related bleeding from gastric cancers best approached?
• Do patients with pancreatic cancer and jaundice need to have an ERCP preoperatively?
• What is the role of ERCP and EUS in patients with suspected cholangiocarcinoma?
• Why are rectal cancers so different from colon cancers with regards to medical and surgical management?

Curbside Consultation in GI Cancer for the Gastroenterologist: 49 Clinical Questions illustrates how patients at different points in their treatment may go back and forth between specialists to receive coordination of care, and incorporates input from gastroenterologists, surgeons, radiologists, and oncologists. While providing up-to-date information, this book will help gastroenterologists to manage complex cancer-related issues and guide physicians through the maze of cancer-related treatments available.

Ideal for practicing gastroenterologists, gastroenterology fellows, surgeons, oncologists, residents, and medical students, Curbside Consultation in GI Cancer for the Gastroenterologist: 49 Clinical Questions is sure to benefit anyone caring for patients with gastrointestinal cancers.

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Computational Methods in Drug Discovery and Repurposing for Cancer Therapy 1st Edition

Computational Methods in Drug Discovery and Repurposing for Cancer Therapy 1st Edition

Computational Methods in Drug Discovery and Repurposing for Cancer Therapy provides knowledge about ongoing research as well as computational approaches for drug discovery and repurposing for cancer therapy. The book also provides detailed descriptions about target molecules, pathways, and their inhibitors for easy understanding and applicability.

The book discusses tools and techniques such as integrated bioinformatics approaches, systems biology tools, molecular docking, computational chemistry, artificial intelligence, machine learning, structure-based virtual screening, biomarkers, and transcriptome; those are discussed in the context of different cancer types, such as colon, pancreatic, glioblastoma, endometrial, and retinoblastoma, among others.

This book is a valuable resource for researchers, students, and members of the biomedical and medical fields who want to learn more about the use of computational modeling to better tailor the treatment for cancer patients.

  • Discusses in silico remodeling of effective phytochemical compounds for discovering improved anticancer agents for substantial/significant cancer therapy
  • Covers potential tools of bioinformatics that are applied toward discovering new targets by drug repurposing and strategies to cure different types of cancers
  • Demonstrates the significance of computational and artificial intelligence approaches in anticancer drug discovery
  • Explores how these various advances can be integrated into a precision and personalized medicine approach that can eventually enhance patient care

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RNA-based Mechanisms in Cancer

RNA-based Mechanisms in Cancer 

The roles of gene transcription in cancer have long been appreciated. However, posttranscriptional processes also contribute significantly to alterations in gene expression that lead to tumor initiation, formation, and progression.

We have known for decades that alterations in the expression of key genes, such as those involved in cell proliferation, signaling, apoptosis, and immune responses, are major molecular events in cancer. This book presents our current understanding of selected posttranscriptional control mechanisms and the RNAs that they regulate. Each chapter provides an overview of a specific RNA-directed regulatory system and the RNA/protein factors involved, then discusses major findings in the field and their relationships to the development and/or treatment of cancer and associated diseases. Future questions serve to address ‘where do we go from here’ and stimulate the reader’s thinking about these important problems.

This compendium of chapters from experts in the field is essential reading for anyone interested in the myriad ways that RNAs contribute to tumorigenesis: from graduate students, researchers, and clinical scientists interested in mRNA processing and translation, RNA-binding proteins that promote turnover/stability of specific mRNAs, how small noncoding RNAs control inflammation and signaling, roles of the epitranscriptome, and future and emerging RNA-based, anti-tumor therapeutics.


Readership: Graduate students, researchers, and clinical scientists in the fields of RNA biology, non-coding RNAs, and cancer research/oncology.

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Head and Neck Oncology: A Concise Guide 1st Edition

Head and Neck Oncology: A Concise Guide 1st Edition

This concise handbook has a unique approach and covers all important aspects of head and neck cancers from basic topics like carcinogenesis to advanced treatment options such as immunotherapy, electrochemotherapy, and robotic surgery in a succinct way. As every treatment center manages its patients with a different modality as per their institutional protocol, this book endeavors to standardize the processes by discussing the management of cancers of all anatomic areas in view of the National Comprehensive Cancer Network (NCCN) guidelines, which is the committee that prepares protocols for management of cancers and every head and which neck oncosurgeons must adhere to for their clinical practice.

Key Features

  • Explains the topics through flowcharts and diagrammatic representations that are helpful for exam preparation

  • This book aims to serve as a valuable resource for postgraduate residents of maxillofacial surgery, ENT and otolaryngology, general surgery, plastic surgery, and junior specialists

  • Serves as a comprehensive, evidence-based quick reference for the clinician on the go

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Cancer through the Lens of Evolution and Ecology 1st Edition

Cancer through the Lens of Evolution and Ecology 1st Edition

Cancer cells exist in an ever-changing “ecology” and are subject to evolutionary pressures just like any species in nature. This edited book explores the following themes: 1) how the dynamics of mutation, epigenetics, and gene expression noise are sources of genetic diversity; 2) how scarce resources influence cancer therapy resistance; 3) how predator-prey dynamics are mirrored in immune-cancer cross-talk; 4) how cancer cells parallel niche construction theory; 5) how changing fitness landscapes enable cancer growth; and 6) how cancer cells interact within the body. The book is a resource for understanding cancer as a disease of multicellularity grounded in evolutionary principles. By using this knowledge, researchers are starting to exploit these behaviors for treatment paradigms.

Key Features

  • Bridges disciplines exemplifying the ways disparate fields create new perspectives when integrated.
  • Offers insights from leading scholars in cancer biology, ecology and evolutionary biology.
  • Provides a timely recognition by oncologists that evolutionary paradigms are crucial for breakthroughs in cancer treatment.
  • Integrates basic and applied sciences of oncology and evolutionary biology.

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Human Papillomavirus: Proving and Using a Viral Cause for Cancer 1st Edition

Human Papillomavirus: Proving and Using a Viral Cause for Cancer 1st Edition

Human Papillomavirus: Proving and Using a Viral Cause for Cancer presents a steady and massive accumulation of evidence about the role of HPV and prevention of HPV-induced cancer, along with the role and personal commitment of many scientists of different backgrounds in establishing global relevance. This exercise involved years of personal commitment to proving or disproving an idea that aroused initial skepticism, and that still has difficult implications for some. It remains one of the big successes of medicine that exploited both established medical science dating back to the nineteenth century and new molecular genetic science during a time of transition in medicine.

  • Presents a comprehensive, up-to-date review of the role of HPV in cancer from those involved in its study
  • Includes the way evidence on the role and utility of HPV based prevention has been accumulated over almost 40 years
  • Gives a series of vignettes of individual scientists involved in the development of the science of HPV and cancer at different stages and their experiences and reasons for involvement

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The Bethesda Handbook of Clinical Oncology Sixth Edition

The Bethesda Handbook of Clinical Oncology Sixth Edition

Selected as a Doody’s Core Title for 2022 and 2023!


Offering up-to-date, authoritative information in a quick-reference format, 
The Bethesda Handbook of Clinical Oncology, Sixth Edition, is a comprehensive yet concise review of the management of different cancer types. Drs. Jame Abraham, James L. Gulley, and a team of expert contributors emphasize practical information that can be applied in everyday patient care situations, and thoroughly revised content keeps you current with advances in this fast-changing field.

  • Provides practical guidance on evaluation, diagnosis, and treatment of patients with cancer from experts and scholars at the National Cancer Institute, National Institutes of Health, Cleveland Clinic, and other renowned institutions.
  • Covers a range of solid-tumor, blood, and other cancers, as well as immunotherapeutic drugs, infection management, nutrition, and palliative care.
  • Contains new and revised content on immunotherapy, precision medicine, genetics, individual cancer therapies, and more.
  • Helps you find what you need quickly with concise, clear content and numerous tables, algorithms, and figures throughout.

Enrich Your eBook Reading Experience

  • such as computer, tablet, or smartphone.
  • powering your content with natural language text-to-speech.

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Cancer Consult: Expertise in Clinical Practice, Volume 1: Solid Tumors & Supportive Care 2nd Edition

Cancer Consult: Expertise in Clinical Practice, Volume 1: Solid Tumors & Supportive Care 2nd Edition

CANCER CONSULT

New edition covering the specialties of hematology, oncology and cellular therapy, now in two volumes

Cancer Consult: Expertise in Clinical Practice, Volume 1: Solid Tumors & Supportive Care, Second Edition includes hundreds of answers to practice-based questions covering the new principles of diagnosis, classification, staging, treatment, and outcomes in the rapidly advancing field of cancer. This textbook series also provides expert guidance in the areas of cancer-related uncertainties and controversies, including experience-based discussions. The book’s smaller size allows for easy access during medical rounds. This volume also includes:

  • Up-to-date, clinically relevant information on the very latest topics such as molecular techniques, targeted therapies, immunotherapy, cellular therapy and translational cancer research
  • Sections on head, neck, thoracic, breast, GI, genitourinary, skin, gynecological and hereditary cancers, amongst other topics
  • Streamlined, engaging content to make finding information easier and less time consuming for the reader
  • Concise and practical expert perspectives that reference key studies
  • References to the latest NCCN, ESMO, ASCO, and other national guidelines

With its powerful focus on pragmatic clinical diagnostic, therapeutic and prognostic approaches, Cancer Consult: Expertise in Clinical Practice, Volume 1: Solid Tumors & Supportive Care, Second Edition will help keep hematology, oncology and cellular therapy practitioners up-to-date, bridging the gaps between journal and reference literature, conferences, and their existing knowledge base. It also offers clinicians, trainees, and fellows an excellent opportunity to enhance their preparation for the ABIM, hematology and oncology fellowship and recertification exams.

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Mouse Models of Cancer: Methods and Protocols (Methods in Molecular Biology Book 2773)

Mouse Models of Cancer: Methods and Protocols (Methods in Molecular Biology Book 2773) 

This detailed volume presents a variety of mouse models for cancer studies, from leukemia and lymphoma models to different types of subcutaneous and orthotopic models. Models for the healing process and the assessment of the immune response after local ablative therapies are also included, as well as imaging techniques that allow for the visualization of cancer at the cellular and tissue level. The book closes with a detailed description of necropsy, which is essential for obtaining good biomaterial for translational research. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. 
Authoritative and practical, 
Mouse Models of Cancer: Methods and Protocols serves as an ideal guide to these controlled and reproducible model experimental systems to study different aspects of cancer biology, including prevention, development, progression, and treatment.

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Cancer Consult: Expertise in Clinical Practice, Volume 2: Neoplastic Hematology & Cellular Therapy 2nd Edition

Cancer Consult: Expertise in Clinical Practice, Volume 2: Neoplastic Hematology & Cellular Therapy 2nd Edition

CANCER CONSULT

New edition covering the specialties of hematology, oncology and cellular therapy, now in two volumes

Cancer Consult: Expertise in Clinical Practice, Volume 2: Neoplastic Hematology & Cellular Therapy, Second Edition includes hundreds of answers to practice-based questions covering the new principles of diagnosis, classification, staging, treatment, and outcomes in the rapidly advancing field of cancer. This textbook series also provides expert guidance in the areas of cancer-related uncertainties and controversies, including experience-based discussions. The book’s smaller size allows for easy access during medical rounds. This volume also includes:

  • Up-to-date clinically relevant information on the very latest topics such as molecular techniques, targeted therapies, immunotherapy, BMT, CAR T-cell therapy and translational cancer research
  • Sections on ALL, AML, myeloid neoplasms, CLL, Hodgkin’s and Non-Hodgkin’s lymphomas, amongst other topics
  • Streamlined, engaging content to make finding information easier and less time consuming for the reader
  • Concise and practical expert perspectives that reference key studies
  • References to the latest NCCN, ESMO, ASH, ASTCT, EBMT and other national guidelines

With its powerful focus on pragmatic clinical diagnostic, therapeutic and prognostic approaches, Cancer Consult: Expertise in Clinical Practice, Volume 2: Neoplastic Hematology & Cellular Therapy, Second Edition will help keep hematology, oncology and cellular therapy practitioners up-to-date, bridging the gaps between journal and reference literature, conferences, and their existing knowledge base. It also offers clinicians, trainees, and fellows an excellent opportunity to enhance their preparation for the ABIM, hematology and oncology fellowship and recertification exams.

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