Oxford Textbook of Neurohaematology (Oxford Textbooks in Clinical Neurology)

The Oxford Textbook of Neurohaematology is a single source of knowledge on the diverse neurological conditions associated with malignant and classical haematological diseases. The book covers the full range of haematological diseases, both malignant and classical, that impact the central, peripheral, and autonomic nervous systems.

The book is divided into three sections. In the first section, neurological conditions associated with malignant haematological diseases are presented. This section begins with chapters on primary haematological malignancies of the nervous system including primary central nervous system lymphomas, vitreoretinal lymphoma, and other rare primary malignancies such as Hodgkin disease and lymphoproliferative disorders. Next, a chapter on histiocytic tumours of the central nervous system presents the neurological conditions associated with the Langerhans and non-Langerhans histiocytoses. This is followed by chapters covering the neurological complications of systemic myeloid and lymphoid malignancies. The second section of the book covers neurological complications of the treatments used in the management of haematological malignancies such as chemotherapy, radiation, and immunotherapy including chimeric antigen receptor T cells. The third and final section of the book features chapters on the neurological complications associated with classical haematological diseases including disorders of red blood cells (e.g., sickle cell anaemia), disorders of platelets and coagulation (e.g., immune thrombocytopenia), and disorders of white blood cells (e.g., hyperviscosity syndrome).

Edited by leading authorities in the field, this book will serve as a useful resource for neurologists, haematologists, and oncologists, as well as for subspecialists and allied health professionals involved in the management of haematological diseases and their neurological manifestations.

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ExpertDDx: Brain and Spine E-Book 2nd Edition

Now fully revised and up-to-date, Expert DDx: Brain and Spine, second edition, quickly guides you to the most likely differential diagnoses based on key imaging findings and clinical information. It presents more than 250 of the top differential diagnoses across a broad spectrum of central nervous system diseases, encompassing specific anatomic locations, generic imaging findings, modality-specific findings, and clinically based indications. Every reader will have expert guidance for defining and reporting useful, actionable differential diagnoses that lead to definitive findings in every area of the brain and spine.

– Presents at least eight clear, sharp, succinctly annotated images for each diagnosis; a list of diagnostic possibilities sorted as common, less common, and rare but important; and brief, bulleted text offering helpful diagnostic clues
– Separates adult and pediatric DDx lists for even faster reference
– Includes expanded differential considerations, new cases, and new images throughout
– Covers hot topics such as different variants of medulloblastoma, convexal subarachnoid hemorrhage, and hyperdense basal ganglia
– Expert Consult™ eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.

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Biophysics of Computation: Information Processing in Single Neurons (Computational Neuroscience Series) 1st Edition

Neural network research often builds on the fiction that neurons are simple linear threshold units, completely neglecting the highly dynamic and complex nature of synapses, dendrites, and voltage-dependent ionic currents. Biophysics of Computation: Information Processing in Single Neurons challenges this notion, using richly detailed experimental and theoretical findings from cellular biophysics to explain the repertoire of computational functions available to single neurons. The author shows how individual nerve cells can multiply, integrate, or delay synaptic inputs and how information can be encoded in the voltage across the membrane, in the intracellular calcium concentration, or in the timing of individual spikes.

Key topics covered include the linear cable equation; cable theory as applied to passive dendritic trees and dendritic spines; chemical and electrical synapses and how to treat them from a computational point of view; nonlinear interactions of synaptic input in passive and active dendritic trees; the Hodgkin-Huxley model of action potential generation and propagation; phase space analysis; linking stochastic ionic channels to membrane-dependent currents; calcium and potassium currents and their role in information processing; the role of diffusion, buffering and binding of calcium, and other messenger systems in information processing and storage; short- and long-term models of synaptic plasticity; simplified models of single cells; stochastic aspects of neuronal firing; the nature of the neuronal code; and unconventional models of sub-cellular computation.

Biophysics of Computation: Information Processing in Single Neurons serves as an ideal text for advanced undergraduate and graduate courses in cellular biophysics, computational neuroscience, and neural networks, and will appeal to students and professionals in neuroscience, electrical and computer engineering, and physics.

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A Handbook of Geriatric Neuropsychology: Practice Essentials (Studies on Neuropsychology, Neurology and Cognition) 2nd Edition

A Handbook of Geriatric Neuropsychology: Practice Essentials (Second Edition) brings together experts in the field to integrate the knowledge and skills needed to understand and treat older adults who are experiencing problems with memory and other thinking skills. With three new sections, including coverage of other conditions beyond neuropsychological disorders, special assessment contexts, and more on interventions and ethics, as well as multiple new chapters, and significant updates from the first edition, this book provides a strong foundation for clinicians, educators, and researchers invested in the wellbeing of older adults.

The impact and experience of aging, like the practice of neuropsychology, evolves over time. Similarly, through advances in science and professional techniques, neuropsychological practice has continued to evolve. Neuropsychological evaluation remains the most effective method of diagnosing age-related cognitive decline, cognitive difficulties that result from psychological factors, and other related disorders, as well as determining how the various disorders impact functioning and quality of life. This book explores these areas and offers state-of-the-art assessment techniques to assess changes in cognition and behavior and to distinguish normal changes from neuropathology.

This book is a go-to resource and key reference for psychologists who serve older adults with known or suspected cognitive problems, as well as those who are invested in promoting brain wellness. It provides much of the information needed to establish and improve foundational and functional competencies in geriatric neuropsychology and establish practices that are personally and professionally rewarding, all aimed at promoting the understanding and wellbeing of older adults.

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How to Think Like a Neurologist: A Case-Based Guide to Clinical Reasoning in Neurology

How to Think Like a Neurologist flips the neurology educational narrative on its head and attempts to lift the veil of neurophobia to show how neurologists use critical thinking and clinical reasoning to diagnose neurologic diseases.

This book aims to provide a practical representation of the modern-day practice of medicine, where the good clinical neurologist is no longer seen as somebody who somehow carries encyclopedic knowledge of every medical condition. Rather, they appropriately recognize and categorize findings, and then, having narrowed the possibilities, they do the necessary additional research in order to appropriately diagnose and treat the patient.

This case-based volume focuses not on the diseases themselves, but rather on the clinical methods used to identify neurologic diseases, and the method is disarmingly simple. The cases in this book are a fascinating collection of oddities and rarities, but the diseases themselves in this book are merely the vessel through which clinical reasoning is taught. By the end of the book, readers are empowered with a foundation they can apply in their own clinical practice.

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Neurology: A Clinical Handbook 1st Edition

“This Handbook is a sparkling addition to the neurological library, a concise and clear guide to clinical practice in neurology, written in elegant prose, a tribute to Queen Square and to the contribution that both Hospital and Institute have made to neurology. It is the encapsulation of wisdom gained in a long career. For practitioners in the art of neurology, junior and senior this is required reading.” 

                 –Simon Shorvon, National Hospital for Neurology & Neurosurgery, Queen Square  

Neurology: A Clinical Handbook is a practical text, for both neurologists and general physicians, in the wards, the office or at home. This book spans the breadth of neurology and its challenges, for those who require a rapid resource in accessible language. 

The Handbook is also aimed at those considering entering neurology, neurophysiology and neurorehabilitation and for medical trainees and consultants in many specialities. It is an invaluable source for the MRCP, a ready-made reference for clinical practice and for the specialist nurse and therapist. 

The book deals with essentials – of neuroanatomy, clinical examination, mechanisms of neurological disease and the major issues of dementia and stroke in an ageing population. More specific aspects of neurology are also addressed, including the specialist fields of nerve and muscle disease, the spinal cord, headache and the cranial nerves, infection in the nervous system, MS and sleep disorders. The allied disciplines of neurorehabilitation, neuropsychiatry, neuro-oncology, uro-neurology, neuro-otology and neuro-ophthalmology are also covered. 

The aim is to provide both an introduction and a summary – of general neurological practice and the specialist aspects of neurology and neuroscience. 

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Harrison’s Neurology in Clinical Medicine, 4th Edition

Neurology – as only Harrison’s can cover it

A Doody’s Core Title for 2017!

Featuring a superb compilation of chapters related to neurology derived from Harrison’s Principles of Internal Medicine, Nineteenth Edition (including content from the acclaimed Harrison’s DVD, now available here in print), this concise, full-color clinical companion delivers the latest knowledge in the field backed by the scientific rigor and authority that have defined Harrison’s. You will find 66 chapters from more than 90 renowned editors and contributors in a carry-anywhere presentation that is ideal for the classroom, clinic, ward, or exam/certification preparation.

Features:

• High-yield board review questions make this text ideal for keeping current and preparing for the boards
• Current, complete coverage of clinically important topics in neurology, including Clinical Manifestations of Neurologic Diseases, Diseases of the Nervous System, Chronic Fatigue Syndrome, Psychiatric Disorders, and Alcoholism and Drug Dependency
• Extensively updated to highlight recent advances in the understanding, diagnosis, treatment, and prevention of neurologic and psychiatric disorders; expanded coverage of neurodegenerative diseases; extensively revised chapter on cerebrovascular diseases; the latest breakthroughs in sleep disorders and migraine
• Integration of pathophysiology with clinical management
• Enhanced by numerous neuroimaging figures throughout the text and an expanded atlas of neuroimaging findings
• Handy appendix of Laboratory Values of Clinical Importance

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Sleep Disorders and Neurologic Diseases (Sleep Disorders, 2) 2nd Edition

Focusing on the relationship between sleep and brain function and the improved management of sleep in patients with neurologic diseases, Sleep Disorders and Neurologic Diseases, Second Edition offers recommendations for the management of primary sleep disorders, sleep disorders secondary to well-established neurological disorders, and the neurological consequences of uncontrolled sleep conditions.

Highlights include:

• Wide-ranging coverage of the diagnosis, treatment, and management of these conditions
• Insight into the effects of sleep disorders on both the healthy and diseased brain
• The neurobiology of sleep and the development of sleep disorders
• Sleep disorders associated with neurodegenerative diseases, restless legs syndrome, and circadian sleep disorders
• Narcolepsy, sleep apnea, and movement disorders, as well as the findings of new epidemiological studies

With chapters analyzing the treatment of specific disease states, this convenient guide also includes additional sections on the role of hypothalamic dysfunction in narcolepsy and the emerging relationship between sleep apnea and hypertension, heart disease, and stroke.

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