Category: Infectious Diseases

HIV/AIDS in China: Epidemiology, Prevention and Treatment

With HIV becoming the leading cause of infectious-disease mortality in Mainland China, this book focuses on tackling HIV/AIDS in the face of rapid political and economic change in China. Featuring contributions by over a dozen leading figures in the field, this book is the go-to text for any student or reader interested in how national and international organizations’ are attempting to control this epidemic.

The book includes chapters on the epidemiology, treatment, and prevention of HIV, as well as several chapters that discuss in detail specific provincial- and national-level programs to control and treat HIV. It chronicles the Chinese government’s amazing about-face, as it replaced underfunded, non-evidence based policy decisions with successful, science-based approaches to disease control and prevention, including the adoption of once controversial needle-exchange programs and the establishment of a national HIV/AIDS data registry. It measures the success of national policy decisions, the implementation of treatment policies, and discusses the difficulty of accessing high-risk communities, including people who inject drugs, sex workers, and men who have sex with men – groups not easy to reach, study, engage in prevention programs, or treatment, for fear of stigmatization and loss of social status. Further, it documents the spread of HIV to other provinces, and the tragedy that befell repeat plasma donors in Henan and other poor provinces, where reused or improperly sterilized lab equipment caused some villages to have epidemic-level incidence rates. This book represents a positive contribution to the field of AIDS research, making vital, new information available to an interested readership.

 

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Drug Interactions in Infectious Diseases Antimicrobial Drug Interactions 4th ed

The 4^th edition of Drug Interactions in Infectious Diseases is being split into two separate volumes – “Mechanisms and Models of Drug Interactions” and “Antimicrobial Drug Interactions”.

This volume, “Antimicrobial Drug Interactions,” delivers a quick clinical resource that distills relevant drug interactions by antimicrobial drug class. The book provides informative tables on specific drug-drug interactions that include the degree and severity of the expected interaction. A mechanistic basis for drug-drug interactions is also provided to link observed interactions to pharmacologic characteristics of key drug classes. This complete resource is organized by major antibacterial, antimycobacterial, antiviral, antifungal, antimalarial, and antiprotozoal class. In line with current innovations in antimicrobial drug development, a distinct chapter on the pharmacologic management of drug interactions in hepatitis B virus (HBV) and hepatitis C virus (HCV)-related infections is included.  Two new chapters are dedicated to the management of human immunodeficiency virus (HIV) drug-drug interactions given the breadth of antiretroviral class-specific effects. This comprehensive review of known drug interactions and strategies to manage them is an invaluable resource to all health care practitioners.

 

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Infectious Disease and Parasites (Encyclopedia of Pathology) 1st ed

This book covers the complete field of the pathology of infectious disease and parasites- from Acquired Immunodeficiency Disease to Zygomycosis. The alphabetically arranged entries, each of which provides a detailed description of a specific pathological disease pattern, allow readers to quickly and easily find the information they need.

 

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Introduction to Clinical Infectious Diseases: A Problem-Based Approach 1st ed

Infectious diseases as a specialty suffers from many unique challenges stemming from lower salaries compared to other medical specialties and difficulty keeping the younger demographic within the field.  With emerging infections, new diagnostic and research tools, and changing migration patterns, these problems are amplified; infectious disease specialists are in higher demand than ever with fewer and fewer specialists available to support patients and colleagues outside of the field.  To meet these increasing challenges, it is vital for the workforce of the future to have the best training possible.  This book aims to provide this support.

As trainees, all physicians face clinical infectious disease scenarios on a daily basis. They receive basic training in common infections, giving them the tools needed for initial diagnostic studies and empiric treatment.  This approach, however, still leaves them struggling with nuances of treating common infections, infections that masquerade as other diseases, rare infection, advanced diagnostics, complicating medical conditions, and a wide range of medical complexities.  Important clinical microbiology details and host susceptibility risks will be highlighted when discussing uncommon infections.

Each chapter begins by defining a distinct clinical infectious disease problem and the most common cause(s). The next section of each chapter identifies the key questions to consider, including other possible pathogens, medical history,  alternate microbiologic diagnoses, instances of unexpected result.  This book is the only academic text designed specifically to meet this challenge by targeting learners at all levels. To do this, the text incorporate 30-40 common clinical infectious disease scenarios in both adult and pediatric hosts.  It includes easy-to-access “tips and tricks” for when to look further or consider possibilities that are unusual that is useful for someone who is new to the information or has limited experience within infectious diseases. The text heavily features teaching and learning tools, including call out boxes that prioritizes infectious etiologies, host risk factors, important microbiologic clues, and important clinical history clues.  The text also includes review questions and quiz-like challenges to reinforce the concepts.

Written by experts in the field Clinical Infectious Diseases is the most cutting-edge academic resource for all medical students, fellows, residents, and trainees, including infectious disease specialists in both adult and pediatric care, internal medicine specialists, and hospitalists.

 

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Diagnostic Pathology of Infectious Disease 2nd Edition

Comprehensive and up to date, the Second Edition of Diagnostic Pathology: Infectious Disease, by Dr. Richard Kradin, is an invaluable tool for the accurate diagnosis of any infectious disease―from the common to the most challenging. The organ-based format makes it an especially useful tool for surgical pathologists’ daily diagnostic and management issues. High-quality, full-color illustrations and differential diagnosis tables accompany each lesion, clearly depicting how to recognize the morphology of organisms and the spectrum of histological responses that they may cause.

Addresses the most difficult diagnostic issues that practicing or trainee surgical pathologists face when handling infectious disease tissue specimens.

Highlights morphological characteristics and landmarks of tissue samples for easy access to information necessary for signing out a specimen.

Emphasizes the host responses critical in differential diagnosis to serve as a second opinion when non-infectious diagnoses mimic and confound the diagnosis of infection.

Completely revised with the latest diagnostic support and hot topics in the field:

A new chapter on novel techniques in microbiology

A new chapter on eye infections

New coverage of immunohistochemical staining and other molecular diagnostic techniques

New discussions of human papillomavirus, a critical tool in predictive cancer screening

New information on infections in the immunocompromised host and related special considerations

Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, images, videos (including video updates), glossary, and references from the book on a variety of devices.

 

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Virus Infection and Tumorigenesis: Hints from Marine Hosts’ Stress Responses 1st ed

This book reviews the latest research on the molecules and mechanisms of marine host stress responses to viral infections and tumorigenesis. It offers an overview of the state of the art in the field as well as future directions.

Metabolism disorder is a characteristic of tumorigenesis. Since viruses complete their life cycle in host cells, such infections cause metabolic disorders in the host. As such, the mechanisms of virus pathogenesis and tumor progression are similar or even identical. In essence, the role of antiviral molecules is to maintain the metabolic homeostasis of infected host cells, and the antiviral molecules induced by virus infection may play an important role in antitumor pathways, resulting in cancer cell death or restoring the disordered metabolism of cancer cells. The molecules generated during host stress responses to viruses can also contribute to the antitumor mechanisms in humans. However, the relationship between host stress responses to virus infection and tumorigenesis has not been extensively explored.

In recent years, studies have shown that marine host stress responses to viral invasion can be good models for exploring human antitumor mechanisms. Stimulating further research in the field, this book offers graduate students and researchers with comprehensive insights into host stress responses to viral invasion and tumor progression. It is also a valuable resource for those working in the pharmaceutical industry interested in drug discovery based on molecules derived from host stress responses to viral infection.

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