Oxford Handbook of General Practice (Oxford Medical Handbooks) 5th Edition

Oxford Handbook of General Practice (Oxford Medical Handbooks) 5th Edition

The well-loved Oxford Handbook of General Practice is a lifeline for busy GPs, medical students, and healthcare professionals. With hands-on advice from experienced practitioners, this essential handbook covers the entire breadth and depth of general practice in small sections that can be located, read, and digested in seconds. Now in its fifth edition, the Handbook has been fully revised to reflect the major new developments shaping general practice today.

Fully updated with the latest guidelines and protocols, this edition offers even more full colour diagrams and tables, and colour-coded chapters on general practice (green), clinical topics (purple), and emergencies (red). Covering the whole of general practice from practice management to hands-on advice dealing with acute medical emergencies, this comprehensive, rapid-reference text will ensure that everything you need to know is only a fingertip away.

Oxidative Stress and Redox Signalling in Parkinson’s Disease (Issues in Toxicology) 1st Edition

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Parkinson’s Disease is the second most common neurodegenerative disorder affecting millions of people worldwide. In order to find neuroprotective strategies, a clear understanding of the mechanisms involved in the dopaminergic death of cells that progresses the disease is needed. Oxidative stress can be defined as an imbalance between the production of reactive species and the ability to detoxify them and their intermediates or by-products. Oxidative damage to lipids, proteins, and DNA has been detected in autopsies from individuals with Parkinson’s Disease and so links can be made between oxidative stress and Parkinson’s Disease pathogenesis.
This book provides a thorough review of the mechanisms by which oxidative stress and redox signalling mediate Parkinson’s Disease. Opening chapters bring readers up to speed on basic knowledge regarding oxidative stress and redox signalling, Parkinson’s Disease, and neurodegeneration before the latest advances in this field are explored in detail. Topics covered in the following chapters include the role of mitochondria, dopamine metabolism, metal homeostasis, inflammation, DNA-damage and thiol-signalling. The role of genetics and gene-environment interactions are also explored before final chapters discuss the identification of potential biomarkers for diagnosis and disease progression and the future of redox/antioxidant based therapeutics.
Written by recognized experts in the field, this book will be a valuable source of information for postgraduate students and academics, clinicians, toxicologists and risk assessment groups. Importantly, it presents the current research that might later lead to redox or antioxidant – based therapeutics for Parkinson’s disease.

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Hypertension and Renal Organ Damage (Practical Case Studies in Hypertension Management) 1st ed. 2018 Edition

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