Category: Pathology

“It is intended for practicing pathologists as well as obstetricians and gynecologists, but because of its detailed description of pathophysiology, it also can serve as a resource for professionals in clinical research. … This is by far the most comprehensive resource in this field. This book has great value for both pathologists with exposure to examination of the placenta and obstetrician/gynecologists who use the reports for management of their patients.” (Raquel K. Walsh Jahnke, Doody’s Book Reviews, March, 2013)

Pathology of the Human Placenta remains the most comprehensive and authoritative text in the field. It provides extensive information on the normal placenta, encompassing physiology, metabolism, and endocrinology, and covers placental diseases in great detail. The conditions discussed include shape aberrations, villous alterations and maldevelopment, erythroblastosis fetalis and hydrops fetalis, transplacental hemorrhage, fetal storage disorders, diverse maternal diseases, and infectious diseases. Further chapters are devoted to abortions, molar pregnancies, trophoblastic neoplasms, benign tumors, and multiple pregnancies. Legal considerations are carefully explored, and this new edition also includes a completely new chapter on artificial reproductive technology. In other respects, too, the book has been extensively revised and expanded, with wide-ranging updates that reflect the most recent progress in the field. Some 800 illustrations are included, many of them in color. The detailed index has been further improved and tables updated. Pathology of the Human Placenta will be of enormous value to pathologists and obstetrician-gynecologists alike.

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This is the third volume in the Essentials of Diagnostic Gynecological Pathology series sponsored by the British Association of Gynecological Pathologists. Focusing on cervical pathology, it provides an update on current diagnostic criteria, the use of biomarkers and specimen handling. It serves as a quick desktop reference facilitating accurate diagnosis, and also provides detailed descriptions and an exhaustive reference list for more in-depth study.

Sections devoted to the changing landscape of cervical screening, current management and future directions are included. Standardized terminology, the biology of HPV-related pre-invasive disease, and the staging of early cervical cancers are discussed.

As most histopathology departments receive many gynecological specimens, Pathology of the Cervix has been written to be useful diagnostically to general as well as specialist gynecological pathologists and pathologists in training. Gynecologists, oncologists, dermatologists, genitourinary physicians and cancer nurse specialists will find expert insights here that will help in treatment and counselling of their patients.​

C Simon Herrington graduated in biochemistry with honours from the University of Cambridge in 1982 and medicine with honours from the University of London in 1985. He trained in Internal Medicine (MRCP 1988) and then became a CRC clinical research fellow in the Nuffield Department of Pathology, University of Oxford, receiving his DPhil in 1991. He was appointed clinical lecturer in pathology in Oxford where he completed his training in clinical cellular pathology (MRCPath 1994). He was appointed clinical senior lecturer in molecular pathology and consultant in pathology at the University of Liverpool in 1995 and was promoted to a Personal Chair in 1999. In 2003, he was appointed to the Chair of Pathology at the University of St Andrews, moving to the Chair of Pathology at the University of Dundee in 2010 and the Chair of Molecular Cancer Pathology at the University of Edinburgh in 2015. He also works as a consultant pathologist, specialising in gynecological pathology, was co-editor of the 4th Edition of the WHO Classification of Tumours of Female Reproductive Organs, and edited the 15th Edition of Muir’s Textbook of Pathology. He sits on the Board of the Association for International Cancer Research and is a past President of the International Society of Gynecological Pathologists. He is Editor in Chief of the Journal of Pathology and the Journal of Pathology: Clinical Research. He has a long-standing interest in the molecular pathology and optical imaging of cancer, collaborating with physical scientists to develop molecular imaging approaches to cancer diagnosis.

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This book provides a comprehensive description of the pathology of the head and neck region, concentrating especially on those pathologic entities that are unique to or characteristic of the head and neck. The new edition retains the ten chapters of the first edition, all updated and improved, and additionally contains seven entirely new chapters and a more detailed subject index. The number of illustrations has been substantially increased, and various lesions absent in the original edition have been included. Throughout, attention is paid to correlation of pathology with epidemiology, clinical features, pathogenesis, and molecular genetics. Differential diagnosis is addressed, and information is also provided on staging, prognosis, and therapy. The authors include foremost experts in the field, some of whom are senior members of the Working Group on Head and Neck Pathology of the European Society of Pathology.

“This text is ideally suited for muscle neurophysiologists interested in doing lab research aimed to study the strength of contraction of the actinmyosin units of skeletal and cardiac myofilaments. … This text is ideal for neurophysiologists and mycologists who have any interest in recordings. I also recommend it for those who work with muscle spindles … .” (Joseph J. Grenier, Amazon.com, December, 2013)

Muscle contraction has been the focus of scientific investigation for more than two centuries, and major discoveries have changed the field over the years. This book centers mostly on mechanical studies, dealing with force production and regulation; it gathers studies performed by scientists who have used diverse muscle techniques, and who have shaped the field of muscle contraction throughout the past years. Starting with theoretical approaches to understand myosin molecule function and energetics, this book covers experimental work performed with single molecules, and discusses results from studies investigating basic mechanisms of contraction, using (mostly in order of appearance) isolated sarcomeres, myofibrils, and fibers are presented. The last chapters summarize studies investigating the effects of acute and chronic adaptations, including weakness and muscle disease. Muscle Biophysics represents an excellent source of information for readers intending to understand the mechanics of muscle contraction, and is a fascinating collection of chapters that will hopefully stimulate young investigators to pursue research in this exciting field of research.

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