On Call Radiology Pap/Psc Edition

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On-Call Radiology presents case discussions on the most common and important clinical emergencies and their corresponding imaging findings encountered on-call. Cases are divided into thoracic, gastrointestinal and genitourinary, neurological and non-traumatic spinal, paediatric, trauma, interventional and vascular imaging. Iatrogenic complications are also discussed.

Each case is presented as a realistic clinical scenario and includes a clinical history and request for imaging. Multi-modality imaging examples and a case discussion on the diagnosis and basic management, with emphasis on important radiological findings, are also presented.

This book combines a case-based discussion format with practical advice on imaging decision making in the acute setting. It also offers guidance on radiology report writing and techniques, with a focus on relevant positive and negative findings to pass on to referring clinicians. On-call Radiology offers invaluable knowledge and practical tips for any on-call radiologist.

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Super-Resolution Imaging in Biomedicine (Series in Cellular and Clinical Imaging)

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This book encompasses the full breadth of the super-resolution imaging field, representing modern techniques that exceed the traditional diffraction limit, thereby opening up new applications in biomedicine. It shows readers how to use the new tools to increase resolution in sub-nanometer-scale images of living cells and tissue, which leads to new information about molecules, pathways and dynamics. The book highlights the advantages and disadvantages of the techniques, and gives state-of-the-art examples of applications using microscopes currently available on the market. It covers key techniques such as stimulated emission depletion (STED), structured illumination microscopy (SSIM), photoactivated localization microscopy (PALM), and stochastic optical reconstruction microscopy (STORM). It will be a useful reference for biomedical researchers who want to work with super-resolution imaging, learn the proper technique for their application, and simultaneously obtain a solid footing in other techniques.

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Textbook of Drug Design and Discovery, Fifth Edition 5th Edition

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Building on the success of the previous editions, the Textbook of Drug Design and Discovery, Fifth Edition, has been thoroughly revised and updated to provide a complete source of information on all facets of drug design and discovery for students of chemistry, pharmacy, pharmacology, biochemistry, and medicine. The information is presented in an up-to-date review form with an underlying and fundamental focus on the educational aspects.

Beginning with an introduction to drug design and discovery, the first eight chapters cover molecular recognition, ligand-based drug design, and biostructure-based drug design. The authors also discuss drug-like properties and decision making in medicinal chemistry, chemical biology, natural products in drug discovery, and in vivo imaging in drug discovery.

The middle six chapters provide an overview of peptide and protein drug design, prodrugs in drug design and development, and enzyme inhibitors. The authors also go through receptors (structure, function, and pharmacology), ion channels (structure and function), and neurotransmitter transporters (structure, function, and drug binding).

The following chapters address important neurotransmitter systems, GABA and glutamic acid receptors and transporter ligands, acetylcholine, histamine, dopamine and serotonin, and opioid and cannabinoid receptors. The book concludes with an examination of neglected diseases, anticancer agents, tyrosine kinase receptors, and antibiotics.

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Pediatric Nail Disorders (Pediatric Diagnosis and Management) 1st Edition

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This is a highly illustrated guide to the diagnosis and management of nail conditions in children. With new material on genetics and on developments such as dermoscopy, it will be invaluable as a reliable clinical reference for both dermatologists and pediatricians, as well as those in family practice.

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Understanding Human Anatomy and Pathology: An Evolutionary and Developmental Guide for Medical Students 1st Edition

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Understanding Human Anatomy and Pathology: An Evolutionary and Developmental Guide for Medical Students provides medical students with a much easier and more comprehensive way to learn and understand the gross anatomy and variations of our body by combining, for the first time, state-of-the-art knowledge about human anatomy, evolution, development, and pathology in one book, synthesizing data that would normally be available for students only by consulting several books at a time.
The book adds evolutionary, pathological, and developmental information in a way that reduces the difficulty and total time spent learning gross anatomy by making learning more logical and systematic, and understanding the ultimate reasons about why our body is as it is, and why we have certain pathologies and musculoskeletal injuries.
The anatomical illustrations are particularly excellent, and clearly a major strength of the book. They were done by a unique team of four multi-awarded, young scientific illustrators, and are carefully selected to follow the style of those seen in human anatomical atlases, but are simpler in their overall configuration, making them easier to understand without overwhelming students with visual information.
The book’s organization is also more versatile than most human anatomy texts so that students can refer to different sections according to their own learning styles, being able to learn either by focusing on different regions of the body or on different groups of structures/types of tissues.
Because it is relatively short in length and easily transportable, students can take this invaluable book anywhere and use it to study and understand most of the structures they need to learn for any gross anatomy course. By providing, for the first time, an unique combination of evolutionary, comparative, anatomical, developmental and pathological information, the book will also be a unique source for evolutionary and developmental biologists, comparative anatomists, functional morphologists, biological anthropologists, pathologists, and medical researchers that are interested to understand the origin of the human body and its variations, as well as human congenital malformations.

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A Healthcare Solution: A Patient-Centered, Resource Management Perspective 1st Edition

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The evidence is undeniable. By any measure, the US spends more on healthcare than any other country in the world, yet its health outcomes as measure by longevity are in the bottom half among developed countries, and its health-related quality of life has remained constant or declined since 1998. In addition to high costs and lower than expected outcomes, the healthcare delivery system is plagues by treatment delays as it can take weeks to see a specialist, and many people have limited or no access to care.

Part of the challenge is that the healthcare delivery system is a large, complex, and sophisticated value creation chain. Successfully changing this highly interconnected system is difficult and time consuming because the underlying problems are hard to comprehend, the root causes are many, the solution is unclear, and the relationships among problems, causes, and solution are multifaceted. To address these issues, the book carefully explains the underlying problems, examines their root causes using information, data, and logic, and presents a comprehensive and integrated solution that addresses these causes. These three steps are the methodological backbone of this book.

A solution depends on understanding and applying the principles of patient-centered care (PCC) and resource management. PCC puts patients, supported by their primary care physicians, back in the role as decision makers and depends on patients being responsible for their health including making good life-style choices. After all, the best way to reduce healthcare costs and increase quality of life is to improve our health and wellness and as a result need less care. In addition, health insurance must be rethought and redesigned so it is less likely to lead to overuse. For many people with health insurance, the out-of-pocket cost of healthcare are small, so healthcare decision making is often biased toward consumption. Effective resource management means that healthcare providers must do a better job of acquiring and using resources in order to provide care quickly, productively, and correctly. This means improving healthcare strategy and management, accelerating the use of information technology, making drug costs affordable and fair, reducing the incidence of malpractice, and rebuilding the provider network.

In addition, implementation is difficult because there are many participants in the healthcare delivery value chain, such as physicians, nurses, and medical technicians, as well as many provider organizations, such as hospitals, clinics, physician offices, and labs. Further up the value chain there are pharmaceutical companies, equipment providers, and other suppliers. These participants have diverse and sometimes conflicting goals, but each must be willing to accept change and work in a coordinated manner to improve healthcare. To overcome these problems, strong national leadership is needed to get the attention and support from the people and organizations involved in healthcare and to make the comprehensive changes that will lower healthcare costs, improve healthcare quality, eliminate delays, increase access, and enhance patient satisfaction.

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Anatomy and Physiology: An Integrated Approach First Edition/Binder-Ready Edition Edition

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Anatomy and Physiology: An Integrated Approach combines the study of anatomy and physiology into one well-organized and illustrated text. It teaches students about the purposes of organ systems, as well as their interconnections. It educates readers about interactions between systems and how disruption to a single system can impact overall function. The book provides detailed information on the topics covered in the traditional, two-course sequence of college-level anatomy and physiology but avoids overwhelming readers with inessential information. Rather, the material focuses on primary concepts and how to apply them. Linked learning strategies, section-specific references, and short summaries throughout each chapter emphasize and reiterate material, enhancing learning and retention. Anatomically accurate, vibrant, realistic artwork helps readers visualize anatomic and physiological principles. Written as an integrative text, Anatomy and Physiology provides a consistent, balanced discussion of both anatomy and physiology within and across chapters. The book is suitable for courses on anatomy, physiology, and human biology, particularly those designed for programs in health care professions.

Julian Pittman holds a doctorate from the Mississippi State University College of Veterinary Medicine. His formal training is in neuroscience and pharmacology/toxicology, and he has taught anatomy and physiology at Christopher Newport University and William and Mary. Currently Dr. Pittman is Associate Chair of the Department of Biological and Environmental Sciences at Troy University in Alabama. In addition to teaching, Dr. Pittman maintains an active research program, where his research interests are focused on understanding the behavioral, neuroanatomical, and neurochemical substrates of anxiety and depression. Dr. Pittman is a member of the Society of Biological Psychiatry.

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Family Medicine: The Classic Papers 1st Edition

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Containing papers carefully compiled for both their historical importance and contemporary relevance, Family Medicine: The Classic Papers brings together a team of experts, led by global family medicine leaders Michael Kidd, Iona Heath and Amanda Howe, who explain the importance of each selected paper and how it contributes to international health care, current practice and research.

The papers demonstrate the broad scope of primary health care delivered by family doctors around the world, showcasing some of the most important research ever carried out in family medicine and primary care. This unique volume will serve as an inspiration to current family doctors and family medicine researchers and educators, as well as to doctors in training, medical students and emerging researchers in family medicine.

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Brain-Computer Interfaces 1: Methods and Perspectives (Cognitive Science) 1st Edition

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Brain–computer interfaces (BCI) are devices which measure brain activity and translate it into messages or commands, thereby opening up many investigation and application possibilities. This book provides keys for understanding and designing these multi-disciplinary interfaces, which require many fields of expertise such as neuroscience, statistics, informatics and psychology.

This first volume, Methods and Perspectives, presents all the basic knowledge underlying the working principles of BCI. It opens with the anatomical and physiological organization of the brain, followed by the brain activity involved in BCI, and following with information extraction, which involves signal processing and machine learning methods. BCI usage is then described, from the angle of human learning and human-machine interfaces.

The basic notions developed in this reference book are intended to be accessible to all readers interested in BCI, whatever their background. More advanced material is also offered, for readers who want to expand their knowledge in disciplinary fields underlying BCI.

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Atlas of Cardiac Innervation 1st ed. 2017 Edition

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This atlas elucidates the role of the neuronal component in normal cardiovascular function and cardiac disorders and discusses the currently available imaging targets and probes. It provides a foundation in cardiac neuronal imaging and image processing and serves as a guide in the effective utilization of these techniques in clinical and research settings. The atlas discusses the principles of autonomic control in the regulation of cardiac function and disease; chemistry and biology of radiotracers designed to target changes in the myocardial sympathetic and parasympathetic innervation as a function of disease or treatment; neuronal imaging in heart failure and reverse remodeling and the use of PET imaging in quantification of cardiac innervation; cardiac sympathetic innervation in ventricular arrhythmias and device therapy; conditions that affect the autonomic nervous system; and the role of myocardial blood flow and cardiac neuronal imaging in denervation and reinnervation in cardiac transplant recipients. Featuring full-color illustrations, schematic diagrams, and diagnostic algorithms, Atlas of Cardiac Innervation is a valuable resource for cardiologists, radiologists, nuclear medicine physicians, and electrophysiologists.

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