Antibacterial Agents: Chemistry, Mode of Action, Mechanisms of Resistance and Clinical Applications 1st Edition

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Antibacterial agents act against bacterial infection either by killing the bacterium or by arresting its growth. They do this by targeting bacterial DNA and its associated processes, attacking bacterial metabolic processes including protein synthesis, or interfering with bacterial cell wall synthesis and function.

Antibacterial Agents is an essential guide to this important class of chemotherapeutic drugs. Compounds are organised according to their target, which helps the reader understand the mechanism of action of these drugs and how resistance can arise. The book uses an integrated “lab-to-clinic” approach which covers drug discovery, source or synthesis, mode of action, mechanisms of resistance, clinical aspects (including links to current guidelines, significant drug interactions, cautions and contraindications), prodrugs and future improvements.

Agents covered include:

  • agents targeting DNA – quinolone, rifamycin, and nitroimidazole antibacterial agents
  • agents targeting metabolic processes –  sulfonamide antibacterial agents and trimethoprim
  • agents targeting protein synthesis – aminoglycoside, macrolide and tetracycline antibiotics, chloramphenicol, and oxazolidinones
  • agents targeting cell wall synthesis – β-Lactam and glycopeptide antibiotics, cycloserine, isonaizid, and daptomycin

Antibacterial Agents will find a place on the bookshelves of students of pharmacy, pharmacology, pharmaceutical sciences, drug design/discovery, and medicinal chemistry, and as a bench reference for pharmacists and pharmaceutical researchers in academia and industry.

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Microbes: Concepts and Applications 1st Edition

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An accessible introduction to the world of microbes—from basic microbe biology through industrial applications

Microbes affect our lives in a variety of ways—playing an important role in our health, food, agriculture, and environment. While some microbes are beneficial, others are pathogenic or opportunistic.

Microbes: Concepts and Applications describes basic microbe biology and identification and shows not only how they operate in the subfields of medicine, biotechnology, environmental science, bioengineering, agriculture, and food science, but how they can be harnessed as a resource. It provides readers with a solid grasp of etiologic agents, pathogenic processes, epidemiology, and the role of microbes as therapeutic agents.

Placing a major emphasis on omics technology, the book covers recent developments in the arena of microbes and discusses their role in industry and agriculture, as well as in related fields such as immunology, cell biology, and molecular biology. It offers complete discussions of the major bacterial, viral, fungal, and parasitic pathogens; includes information on emerging infectious diseases, antibiotic resistance, and bioterrorism; and talks about the future challenges in microbiology.

The most complete treatment of microbial biology available, Microbes features eye-opening chapters on:

  • Human and Microbial World
  • Gene Technology: Application and Techniques
  • Molecular Diagnostic and Medical Microbiology
  • Identification and Classification of Microbes
  • Diversity of Microorganisms
  • Microbes in Agriculture
  • Microbes as a Tool for Industry and Research

Complete with charts and figures, this book is an invaluable textbook for university teachers, students, researchers, and people everywhere who care about microorganisms.

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Principles and Practice of Clinical Virology 5th Edition

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The knowledge and practice of clinical virology continues to expand. This new fifth edition has thirty-six comprehensive chapters, each of which has been extensively revised or rewritten, with the addition of new colour plates.

This updated version takes into account knowledge accumulated in molecular biology with its applications for laboratory diagnosis, immunisation and antiviral chemotherapy. Each chapter highlights the clinical features and epidemiological patterns of infection. Similarly, in response to the global concern of the threat posed by new viruses, a new chapter on Emerging Infections is included.

There is also new material on Hospital Acquired Infections, including some advice relating to SARS, that will be of benefit to those dealing with the day-to-day management of patients in hospital.

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International Handbook of Workplace Trauma Support 1st Edition

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The International Handbook of Workplace Trauma Support provides a comprehensive overview of contemporary standards and best practices in trauma support that draws from the latest research findings and experience of international experts in the field.

  • Reviews the major contemporary post-trauma intervention models in both theory and practice
  • Includes Trauma Risk Management (TRiM), Support Post Trauma (SPoT), Eye-Movement Desensitization and Reprocessing (EMDR), Mindfulness and Psychological First Aid (PFA)
  • Incorporates multi-cultural perspectives by reporting on the pervasive violence in South Africa, constant threats in Israel and emerging developments in China
  • Includes social, psychosocial, psychological, and organizational dimensions to offer a detailed mapping of trauma support
  • Provides latest thinking for supporting those in the military context

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Case Studies in Palliative and End-of-Life Care 1st Edition

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Case Studies in Palliative and End-of-Life Care uses a case-based approach to provide students and practitioners with an important learning tool to improve critical thinking skills and encourage discussion toward improving experiences for patients and their families.

The book is organized into three sections covering subjects related to communication, symptom management, and family care.   Each case is presented in a consistent, logical format for ease of use, highlighting key evidence-based concepts including the case history, care setting, diagnosis and prognosis, assessment, treatment considerations, and family support.

A key reference, Case Studies in Palliative and End-of-Life Care is an invaluable resource for clinicians who provide palliative care to patients with life-limiting illnesses and those at the end of life along with their families.

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Management of Heart Failure 1st Edition

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This volume presents a fresh international perspective on current approaches to treating heart failure. An accessible reference for hospital-based specialists, the book provides an update on recent advances in therapeutics and pharmacology, as well as ongoing trials. Four major sections concentrate on a review of screening, assessment and diagnosis; an update on drug treatments; an update on device therapy; and a description of best practice recommendations for managing clinically challenging cases

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The Maudsley Prescribing Guidelines in Psychiatry 11th Edition

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The evidence base for drug treatments in psychiatry ranges from meta-analyses and randomised controlled clinical trials to single case reports, and from NICE guidelines to individual SPCs.  Where do you look for information when transferring a patient from one drug to another?  Where do you find a clear overview when dealing with a complex patient (e.g, with co-morbid epilepsy or liver disease or HIV infection)?   Where can you seek advice on prescribing psychotropics during pregnancy?  The Maudsley Prescribing Guidelines in Psychiatry! The leading clinical reference for handling prescribing problems as encountered in daily practice and for formulating prescribing policy.

Evidence-based and written by experts

This book is the essential guide for anyone responsible for prescribing, dispensing or administering drugs for patients with mental health disorders.  All the evidence has been reviewed and summarized succinctly by an expert team of psychiatrists and pharmacists.

New content and improved format

This new edition makes greater use of tables and boxes to facilitate quick reference and includes new sections on cytochrome-mediated interactions and psychiatric side effects of non-psychotropic drugs.

Clinically relevant

Chapters address plasma monitoring, schizophrenia, bipolar disorder, depression and anxiety, children and adolescents, substance abuse and special patient groups.  Each section has a full reference list.  The book covers prescribing drugs outside their licensed indications and their interaction with substances such as alcohol, nicotine and caffeine.

Useful for all levels of experience

Trainees will gain important information regarding the rational, safe and effective use of medications for patients with mental illness.  Experienced clinicians will find excellent guidance regarding more complex issues that they may not encounter regularly.

Why the Maudsley Prescribing Guidelines in Psychiatry?

Long recognized as an international trailblazer in mental health care, the Maudsley Hospital earned its reputation for excellence in both in-patient and community care.  It is highly regarded for its research, and pioneered the use of clinical neuroscience. You can trust The Maudsley Prescribing Guidelines in Psychiatry to be scientifically sound and clinically effective.

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Good Medical Practice: Professionalism, Ethics and Law 1st Edition

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Good Medical Practice: Professionalism, Ethics and Law brings together information that is central to the professional, ethical and legal requirements of being a doctor. It covers a core curriculum for medical students, doctors in training and international medical graduates preparing for the Australian Medical Council examinations. A useful guide for busy doctors, giving sound advice for issues that arise in practice, ensuring that all approaches meet professional standards. Effective and compassionate practice depends equally upon good communication skills, an empathetic attitude, truthfulness, self-reflection and an awareness of the responsibilities arising under relevant laws. Good Medical Practice encapsulates these attributes and includes practice management, inter-professional relationships, sexual misconduct, complaints processes, the Australian health care system and doctors’ health within its broad and comprehensive purview. Written by specialist practitioners with vast teaching experience, this is a unique, timely and accessible text that reinforces a contemporary focus on professionalism in medical practice.

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The Parasomnias and Other Sleep-Related Movement Disorders (Cambridge Medicine (Hardcover)) 1st Edition

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The first authoritative review on the parasomnias – disorders that cause abnormal behavior during sleep – this book contains many topics never before covered in detail. The behaviors associated with parasomnias may lead to injury of the patient or bed-partner, and may have forensic implications. These phenomena are common but often unrecognized, misdiagnosed, or ignored in clinical practice. With increasing awareness of abnormal behaviors in sleep, the book fulfils the need for in-depth descriptions of clinical and research aspects of these disorders, including differential diagnosis, pathophysiology, morbidity, and functional consequences of each condition, where known. Appropriate behavioral and pharmacological treatments are addressed in detail. There are authoritative sections on disorders of arousal, parasomnias usually associated with REM sleep, sleep-related movement disorders and other variants, and therapy of parasomnias. Sleep specialists, neurologists, psychiatrists, psychologists and other healthcare professionals with an interest in sleep disorders will find this book essential reading.

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Drug Use and Abuse: A Comprehensive Introduction (SAB 250 Prevention & Education) 7th Edition

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Packed with the latest data, the powerful new Seventh Edition of Howard Abadinsky’s DRUG USE AND ABUSE: A COMPREHENSIVE INTRODUCTION delivers a thorough, interdisciplinary survey of all aspects of drug and alcohol abuse. The text draws from the many disciplines of history, law, pharmacology, political science, social work, counseling, psychology, sociology, and criminal justice — resulting in the most comprehensive, authoritative resource available. Coverage includes the history of drugs, their impact on society, the pharmacological impact of drugs on the body, drug policy implications, the criminal justice system response, the drug business, law enforcement, theories of use, as well as the effects, treatment, and prevention of abuse.

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