Pediatric Cancer in Africa: A Case-Based Guide to Diagnosis and Management 1st ed. 2017 Edition

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This text is the only book of its kind to provide specific guidance applicable to limited resource settings and builds up from the foundation of general practitioner or general pediatrician competence. Written and edited by leaders in the field, this manual educates physicians on the essential components of the discipline, filtered through the experience of specialists from developing countries, with immediate applicability in the specific healthcare environment in these countries. Typically, manuals of pediatric hematology-oncology are written by specialists from high-income countries, and usually target an audience with a sub-specialist level of training, often assisted by cutting-edge diagnostic and treatment facilities. However, approximately 80% of new cases of cancer in children appear in mid- and low-income countries. Almost invariably, general practitioners or general pediatricians without special training in oncology will look after children with malignancies who enter the health care system in these countries. The diagnostic facilities are usually limited, as are the treatment options. The survival figures in these conditions are somewhere below 20%, while in high-income countries they are in the range of 80% for many childhood cancers. This book includes simplified therapy protocols, pain therapy and palliation, as well as ward procedures such as bone marrow aspiration/biopsies, intravenous therapy and chemotherapy drugs mixing. It provides an overview of pediatric cancer epidemiology, cancer registration and organizing support networks and features the management of cancers with associated pathology like AIDS, malnutrition, malaria and tuberculosis.

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Surgery of the Inferior Vena Cava: A Multidisciplinary Approach 1st ed. 2017 Edition

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This book addresses an urgent need, offering an updated, detailed and multidisciplinary review of surgery of the inferior vena cava (IVC). Over the past two decades, tremendous advances have been made in this field and related specialties. Many journals and/or textbooks on different surgical or medical specialties have reported on individual aspects, so it is high time to gather all of them in a single resource.

To date, surgery of the IVC remains a major challenge, not only in terms of technical difficulties, but also in terms of perioperative management.  The book sheds new light on cutting-edge developments, including: Innovations in imaging; Neoadjuvant and adjuvant treatments for tumors of or involving the IVC; Intraoperative anesthetic management; and Technical and technological advances in surgery. As such, it will be of a great interest to surgeons (cardiac, vascular and digestive) and urologists, as well as radiologists and anesthesiologists.

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Rotatory Knee Instability: An Evidence Based Approach 1st ed. 2017 Edition

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This book is designed to equip the reader with the knowledge and tools required for provision of individualized ACL treatment based on the best available evidence. All major aspects of the assessment of rotatory knee instability are addressed in depth. A historical overview of arthrometers, both invasive and non-invasive, is provided, and newly developed devices for the measurement of rotatory knee laxity are considered. Recent advances with respect to the pivot shift test are explained and evidence offered to support a standardized pivot shift test and non-invasive quantification of the pivot shift. Specific surgical techniques for rotatory laxity are described, with presentation of the experience from several world-renowned centers. In addition, functional rehabilitation and “return to play” are discussed. In keeping with the emphasis on an individualized approach, the book highlights individualization of surgical reconstruction techniques in accordance with the specific injury pattern and grade of rotatory knee laxity as well as the use of individualized rehabilitation techniques. Numerous high-quality images illustrate key points and clear take-home messages are provided.

About the Author

Volker Musahl, MD, is Associate Professor of Orthopaedic Surgery at the University of Pittsburgh School of Medicine, Associate Professor of Bioengineering at the University of Pittsburgh’s Swanson School of Engineering, the Program Director of the Sports Medicine fellowship program, and Medical Director of the UPMC Center for Sports Medicine. In addition to his work as a University of Pittsburgh Associate Professor and a leading Orthopaedic surgeon, Dr. Musahl is co-head team physician for the University of Pittsburgh football team. Dr. Musahl is the recipient of various honors and awards and has recently been appointed Assistant Editor-in-Chief of the Knee Surgery Sports Traumatology and Arthroscopy Journal (KSSTA). His research interests include knee and shoulder biomechanics. He is a member of ESSKA ISAKOS, AAOS, ORS, AOSSM, AANA, and AGA.

Jon Karlsson, MD, PhD, is Professor of Orthopaedics and Sports Traumatology at the Sahlgrenska Academy, Gothenburg University, Gothenburg, Sweden. His clinical interests and his research are mainly related to knee injuries and foot and ankle, including tendon injuries. Dr. Karlsson graduated from Medical School in Reykjavik, Iceland. He then moved to Sweden for orthopaedic training, becoming a specialist in Orthopaedics in 1986. He has worked at the Sahlgrenska University Hospital ever since, and is currently Senior Consultant. He has been Clinical Head of the Orthopaedic Department and is now its Academic Head. He has mentored 40 PhD students and is the author of more than 300 papers and almost 30 books. He is an active member of ESSKA and ISAKOS and is currently Secretary of the ISAKOS Executive Board and Editor-in-Chief of KSSTA, the official, clinical journal of ESSKA.Ryosuke Kuroda, MD, PhD, is an Associate Professor in the Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kobe, Japan. Dr. Kuroda graduated from Kobe University School of Medicine in 1990 and then specialized in Orthopaedic Surgery. After completion of a postgraduate course at Kobe University Graduate School he worked as a Post-Doctoral Research Fellow in Cleveland Clinic Foundation and the University of Pittsburgh. He has been a member of the Board of Councillors of the Japanese Orthopaedic Society of Knee, Arthroscopy, and Sports Medicine (JOSKAS) since 2009. He served as an ISAKOS Knee Committee member from 2009 to 2011 and is currently on the ISAKOS Board of Directors. Since 2013 he has been the lead or co-author of more than 90 articles in peer-reviewed journals.
Stefano Zaffagnini, MD, is an Associated Professor at the University of Bologna, Italy and coordinator of the Sports Traumatology Excellence Centre of the Istituto Ortopedico Rizzoli, Bologna, Italy. He has been an AOSSM-ESSKA travelling fellow, Chairman of the ESSKA Arthroscopy Committee, and President of the Italian Society of Knee Surgery (SIGASCOT). He is a member of numerous national and international societies and his main interests in clinical practice and res

earch are sports traumatology, ACL reconstruction, knee biomechanics, computer-assisted surgery, meniscal replacement, cartilage surgery, and partial/total knee replacement. He is the author of more than 150 indexed papers and 30 book chapters and the editor of five books.

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Dying and Death in Oncology 1st ed. 2017 Edition

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This book brings together in one volume many important topics about death and dying, including the pathophysiology of death, the causes of death among cancer patients, the ethics of death, the legal aspects of death for the physician and for the patient and caregivers, the economics of death, the medical management of the dying patient, including pain and dyspnea, the prediction of death, and the spiritual management of the dying patient. It also discusses other medical and humanistic aspects of death and dying, such as the historical definition of death and various cultures’ and religions’ viewpoints on death and the afterlife.   Everybody, including every patient with cancer, will die, and every physician will have to assist dying patients. Oncologists face this prospect more often than many physicians. And yet to date there has been no comprehensive textbook on Thanatology, the academic discipline studying death and dying, to assist oncologists in this difficult task. This book will help the physician to understand his or her own relationship with death and to communicate about death and dying with the patient and the patient’s caregivers.

About the Author

Lawrence Berk, a radiation oncologist, completed a PhD in Physical Chemistry from Yale University studying the high field conductivity of aqueous solutions and then researched batteries and fuel cells for Westinghouse Electric Corporation. He then studied medicine at the University of Pittsburgh and completed his residency in radiation oncology at the University of Pennsylvania. He has worked in private practice and in academics, and he is currently Professor and Chief of Radiation Oncology at the Morsani School of Medicine of the University of South Florida. His research has been in palliative care and symptom management. He has led national trials studying brain metastases, cancer cachexia and radiation esophagitis.

Dr. Berk is board certified in both Radiation Oncology and Palliative Medicine. He has previously served as Vice Chair of the US National Cancer Institute-funded cooperative research organization the Radiation Therapy Oncology Group and as the Chair of the Symptom Management Committee of the Radiation Therapy Oncology Group. He also served on the National Cancer Institute’s PDQ Board for Complementary and Alternative Medicine. He has published numerous articles in areas ranging from the polio vaccine trials in 1935, to the epidemiology of toilet training and to preventing side effects of radiation therapy and the palliative treatment of cancer patients.

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Hematologic Abnormalities and Acute Lung Syndromes (Respiratory Medicine) 1st ed. 2017 Edition

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This book provides a unique frame work for examining acute lung syndromes that arise from hematologic disorders or is defined by a hematologic abnormality as a key feature.  Acute lung processes arising from hematologic disorders can present as life-threatening conditions, and as such, the pulmonary physician or critical care physician are often directly involved in care or called upon to provide expertise. Chapters are organized into three sections, each with an emphasis on pathogenesis and current understanding of mechanisms. The text begins with the central theme of the lungs as the direct interface between the external environment and blood, description of individual components of the hematopoietic system, their function and relevance to the lungs. The second section outlines both benign and malignant primary hematologic disorders that can lead to acute pulmonary manifestations. The final section focuses on acute lung syndromes stemming from complications of transfusion and treatment. Chapters are presented in an easy-to-access format, providing information on diagnosis, management, and outcomes. This is a valuable resource for pulmonary fellows in training, pulmonologists, critical care physicians, and physicians involved in caring for patients in the ICU.

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Vulvar Pain: From Childhood to Old Age 1st ed. 2017 Edition

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This book offers detailed coverage of all aspects of vulvar pain in age groups from children to the elderly, with a particular focus on factors that precipitate or maintain the pain. Guidance is provided on diagnosis and treatment, and careful consideration is given to special circumstances associated with vulvar pain, including childbirth, recurrent cystitis, female genital mutilation, medical comorbidities, and sexual comorbidities in both partners. Vulvar pain of neurogenic and iatrogenic origin is also fully discussed. Two innovative chapters present case reports highly relevant to clinical practice and address outstanding issues, including controversies and difficulties in terminology, initial triggers, the role of stress, psychogenic causes, and misuse and abuse. The book is exceptional in covering vulvar pain throughout the human life span and in a wide range of situations, and it will be of value to all who are involved in management of the condition.

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Autism Spectrum Disorders in Adults 1st ed. 2017 Edition

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In this book a group of international experts guide the reader through the clinical features of adults with autism spectrum disorders, describe the care needs of patients and their families, explain the evolution of the disorders into old age, and highlight what can be done to help. Detailed attention is paid to the medical and psychiatric problems of adults with these disorders and the approach to their education and professional integration. In addition, expert neuroscientists summarize current views on the neurobiology of autism.

Autism spectrum disorders are devastating neurodevelopmental disorders. Although diagnosis and therapeutic interventions usually take place in infancy, they are chronic lifelong conditions. Surprisingly, the literature on autism spectrum disorders in adults is scarce. Moreover, most mental health professionals working with adults have little training in autism, and adult mental health services around the world are rarely prepared to address the needs of these patients, which tend to increase with age. This book therefore fills a crucial gap in the literature and will prove useful for all who care for and deal with adults in the Autistic Spectrum.

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Nanoscale Insights into Ion-Beam Cancer Therapy 1st ed. 2017 Edition

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This book provides a unique and comprehensive overview of state-of-the-art understanding of the molecular and nano-scale processes that play significant roles in ion-beam cancer therapy. It covers experimental design and methodology, and reviews the theoretical understanding of the processes involved. It offers the reader an opportunity to learn from a coherent approach about the physics, chemistry and biology relevant to ion-beam cancer therapy, a growing field of important medical application worldwide.

The book describes phenomena occurring on different time and energy scales relevant to the radiation damage of biological targets and ion-beam cancer therapy from the molecular (nano) scale up to the macroscopic level. It illustrates how ion-beam therapy offers the possibility of excellent dose localization for treatment of malignant tumours, minimizing radiation damage in normal tissue whilst maximizing cell-killing within the tumour, offering a significant development in cancer therapy. The full potential of such therapy can only be realized by better understanding the physical, chemical and biological mechanisms, on a range of time and space scales that lead to cell death under ion irradiation. This book describes how, using a multiscale approach, experimental and theoretical expertise available can lead to greater insight at the nanoscopic and molecular level into radiation damage of biological targets induced by ion impact.

The book is intended for advanced students and specialists in the areas of physics, chemistry, biology and medicine related to ion-beam therapy, radiation protection, biophysics, radiation nanophysics and chemistry, atomic and molecular physics, condensed matter physics, and the physics of interaction of charged particles with matter. One of the most important features of the book is the inclusive multiscale approach to the understanding of complex and highly interdisciplinary processes behind ion-beam cancer therapy, which stretches from the atomistic level up to the biological scale and is demonstrated to be in excellent agreement with experimental observations.

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Cardio-Oncology: The Clinical Overlap of Cancer and Heart Disease 1st ed. 2017 Edition

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Co-edited and written by an interdisciplinary team of experts in oncology and cardiology, this book is a clinically useful resource on these overlapping topics:

• Cardiac complications in patients receiving cancer therapy

• The treatment of cancer in patients with cardiovascular disease

• The treatment of cardiovascular disease in patients with cancer

When relevant to medical practice, epidemiology and basic science are also included in the discussion and each chapter is written by an oncologist and a cardiologist. Additionally, the chapters follow a similar format to make the book truly interdisciplinary, user-friendly, and clinically applicable to specialists and non-specialists who care for patients with both cancer and cardiovascular disease.

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Robotic Colon and Rectal Surgery: Principles and Practice 1st ed. 2017 Edition

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The initial chapters discuss the start of minimally invasive surgery and robotics. Subsequent chapters address starting up a robotics program and incorporating robotics into ones practice. The textbook next centers on specific robotic techniques or robotic management of certain disease processes. These chapters are written by experts in the fields and include multiple tables, illustrations, and videos describing the techniques where applicable.  Each chapter also discusses the current literature. The final chapters focus on the future of robotics, cost of robotics, and include other possible future platforms and as well as the new FDA approved Xi and SP Intuitive surgical platforms.

Robotic Colon and Rectal Surgery: Principles and Practice presents the first in-depth, cohesive and comprehensive approach to all aspects of robotic colorectal surgery.

About the Author

Vincent J. Obias The George Washington Medical Faculty Associates Assistant Professor of Surgery Chief Division Colon and Rectal Surgery Vincent J. Obias, MD is board-certified in general surgery and colon & rectal surgery. He specializes in laparoscopic and robotic colon & rectal surgery for neoplastic and benign disease, trans anal endoscopic microsurgery, inflammatory bowel disease including Crohn’s disease and ulcerative colitis, as well as constipation and functional anorectal disorders. Dr. Obias has written articles on a variety of subjects including rectal cancer, post-operative recovery, trauma-critical care, and transplant surgery. He has presented papers at the Minimally Invasive Robotics Association national conference (MIRA), the American Society of Colon and Rectal Surgeons national conference, the Surgical Infection Society joint meeting in Europe, the Society of American Gastrointestinal Endoscopic Surgeons, and the American College of Surgeons. Dr. Obias completed a subspecialty residency in Colon & Rectal Surgery at The Cleveland Clinic and a fellowship in Advanced Laparoscopic Colon and Rectal Surgery at University Hospitals Case Medical Center. He performed his internship and General Surgery residency at Eastern Virginia Medical School. He completed a master in Physiology and earned his medical degree at the Medical College of Virginia. Dr. Obias earned his Bachelor’s in Biology at James Madison University. Dr. Obias is a US News & World Report ‘Top Doctor’ and was determined to be in the top 10% in his region in colon & rectal surgery! He is also a Washingtonian Top Doc list and Castle Connolly Top Doc.

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