Category: Oncology

Hereditary Colorectal Cancer: Proceedings of the Fourth International Symposium on Colorectal Cance

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Since the success in chemical induction of cancer in rabbit’s ear skin by K. Yamagiwa in 1915, oncologists of the world have come to believe that they can only solve their problems by means of animal experimen­ tation. The importance of environmental factors became moreevident in 1935 when T. Yoshida and T. Sasaki introduced azodye hepatocarcino­ genesis in rats. In the domain of the gastrointestinal tract, T. Sugimura has more recently accumulated enough evidence to indicate that locally active chemical mutagens are carcinogenic. In contrast, principal approaches to colorectal tumors have been quite different: emphasis has been placed on gene identification. Long before cancer of the large bowel was recognized, importance of the roles of adenomatosis coli and its familial occurrence attracted the attention of epidemiologists and geneticists. Morphological characteri­ zation and analysis of hereditary trends of human material have already bad a long history, and recently detailed analysis of genetic material has become feasible in the wake of rapid development in our knowledge of the oncoviruses, oncogenes, suppressor genes, chromosomal and DNA mapping, molecular mutation and so on. lt is true that in colorectal pathology, and in no other field, these areas of research have been explored more extensively and decisively. The identification of previ­ ously ill-defined lesions such as precancers and benign neoplasms have been improved because sequential changes can be observed in multiple samples spread over a wide area and followed up in due course.

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Colorectal Cancer: Diagnosis and Clinical Management 1st Edition

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Colorectal Cancer: Diagnosis and Clinical Management provides colorectal surgeons, gastroenterologists and oncologists with an authoritative, practical guide to best practice in the diagnosis and clinical management of colorectal cancer.

Covering all forms of treatment including surgery, chemotherapy and radiotherapy, it examines the various new and emerging therapies, new strategies for screening and prevention, as well as the latest guidance on the most challenging and controversial aspects of managing colorectal cancer.

The authors present important information on:

  • Controversies in adjuvant chemotherapy
  • Long versus short course radiotherapy
  • Minimally invasive surgery and robotics
  • Radical colonic resection

Each chapter contains key points, tips and tricks and clinical case studies to aid rapid browsing and knowledge of the basic principles, while self-assessment questions allow readers to test their clinical knowledge.

With leading international surgeons, gastroenterologists and oncologists combining to offer their considerable wealth of expertise and knowledge, Colorectal Cancer is a well-balanced, indispensable resource for all those involved in colorectal cancer management.

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UICC Manual of Clinical Oncology 9th Edition

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The Manual of Clinical Oncology, Ninth Edition, published with the International Union Against Cancer (UICC), provides a concise, accessible and feasible reference covering state of art multidisciplinary clinical oncology in order to meet the needs of clinicians caring for cancer patients throughout the world.

Edited by world-renowned practising oncologists and written by key opinion leaders, this book contains authoritative and up-to-date information on cancer detection, diagnosis and treatment alongside topics such as survivorship, special populations and palliative care.

Remodelled and revised for the ninth edition to provide practical information to oncology workers, the UICC Manual of Clinical Oncology is structured in two parts. Part 1 covers general principles of cancer diagnosis and management with additional attention to special settings in oncology, including supportive care and survivorship, and Part 2 covers site-specific multidisciplinary cancer management. The edition includes up-to-date summaries of all treatment modalities (medical, surgical and radiation) for all tumour sites. It also contains the latest TNM classifications outlined in the TNM Classification of Malignant Tumours.

The ninth edition includes:

Practical presentation with bullet points, tables, and flow charts intended to facilitate quick reference for day-to-day clinical practice in busy oncology environments,
Representation of multidisciplinary care for site specific management,
Evidence-based approaches to management, including specific treatment recommendations and investigations guided by clinical practice guidelines,
State of art evidence-based recommendations that take into consideration the lack of availability of certain medications or resources, as well as practice variations, in different and remote regions of the world, and
Contemporary topics on cancer treatment, such as cancer informatics, evidence levels, principles of prognostication, survivorship and cancer in pregnancy.

Oncologists, oncologists-in-training, nurses working with cancer patients and other health professionals responsible for treating and caring for those with cancers will find the UICC Manual of Clinical Oncology an indispensable and comprehensive resource.

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Cancer Vaccines: Methods and Protocols (Methods in Molecular Biology) 2014th Edition

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Cancer Vaccines: Methods and Protocols explores the manipulation and modification of immune cells, the manipulation and modification of tumor cells as well as the manipulation of immune/tumor interactions and various delivery mechanisms, with the overall end goal of evoking a tumor-specific response and overcoming the immuno-evasive mechanisms employed by the tumor cells. This detailed volume also covers the subject of cancer vaccines in a more global sense with its section on the advances, challenges, and future of cancer vaccines. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols and tips on troubleshooting and avoiding known pitfalls.

Comprehensive and authoritative, Cancer Vaccines: Methods and Protocols aims to help guide researchers toward developing further generations of cancer vaccines that are both safe and efficacious, with the hope that cancer vaccines will be the standard of care in the very near future.

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The MD Anderson Manual of Medical Oncology, Third Edition 3rd Edition

 

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Authoritative, hands-on desk reference for the practicing oncologist―from the leader in the field of cancer management and treatment

The MD Anderson Manual of Medical Oncology details the personalized multidisciplinary approach to cancer management and treatment of common and rare cancers pioneered by The University of Texas MD Anderson Cancer Center. Its pragmatic presentation can provide valuable insights at any stage of your career.

This completely updated third edition reflects the most recent advancements, including expanded coverage of the rapidly evolving area of biological and immune therapies of cancer, many developed at MD Anderson. It emphasizes and discusses continuing developments in diagnostic procedures, which include the incorporation of new molecular markers and revised staging systems. It also reinforces how imaging and molecular profiling can prevent administration of overly aggressive, toxic treatment regimens or invasive surgery to treat superficial or indolent tumors.

To help you quickly assess cancer management options, every chapter includes numerous tables, diagrams, imaging photographs, and prescriptive advice. Evidence-based treatment algorithms in the form of flowcharts and diagrams shaped by the clinical experience of MD Anderson’s world-class faculty enhance the text.

The third edition features important new chapters on key topics such as:

  • Pediatric Cancers
  • Molecular Biomarkers and Cancer
  • Immuno-Oncology
  • Targeted Therapies in Cancer
  • Onco-Cardiology
  • Pulmonary Complications of Cancer Therapy
  • Applied Biostatistics

Offering the perfect balance of narrative text, summary tables, and clinical photographs (many in full color), there is truly not a more accessible, up-to-date, or authoritative clinician’s guide to the medical management of patients with cancer and its complications than The MD Anderson Manual of Medical Oncology.

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Radiation Oncology Primer and Review: Essential Concepts and Protocols 1st Edition

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Radiation Oncology Primer and Review describes the fundamental concepts, nomenclature and definitions of the field of radiation oncology that every trainee or practitioner needs to know. Divided into three sections, Radiation Oncology Primer and Review covers basic science, clinical science, and technical and planning issues to give the trainee a full overview of the core knowledge base of the field.

Co-written by a former radiation oncology residency program director and a team of radiation oncology residents, the book is organized in concise sections and is amply illustrated to highlight key points and help the reader understand and retain major concepts. Treatment approaches consistent with published clinical trial protocols that define control/standard of care/consensus radiation treatment are included. In addition to serving as a primary introduction to the field, the book also offers a short review of fundamental concepts for the senior resident prior to written or oral examinations, and is a useful resource for the radiation oncology educator to develop teaching plans and quizzes. Chapter organization is based on the International Atomic Energy Agency Syllabus for the Education and Training of Radiation Oncologists, the syllabus endorsed by both the American Society for Radiation Oncology and the European Society for Therapeutic Radiology and Oncology.

Radiation Oncology Primer and Review:

  • Integrates basic science, clinical science and technical concepts to provide the trainee with a complete introduction to the field of radiation oncology
  • Is consistent with accepted training syllabus for radiation oncology professionals
  • Offers a concise presentation with illustrations highlighting key poiints
  • Provides key points for study and reviews
  • Includes treatment approaches consistent with published clinical trial protocols that define control/standard of care/consensus radiation treatment
  • Is a valuable review resource for board review

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Gynecologic Oncology Handbook: An Evidence-Based Clinical Guide 1st Edition

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Gynecologic Oncology Handbook provides a comprehensive yet concise, practical guide for fellows, residents, specialist trainees, and clinicians in the diagnosis and management of gynecologic cancers. The book addresses the fundamentals of gynecologic oncology, including staging, surgical therapies, comorbidity diagnosis and management, adjuvant therapies including chemotherapy and radiation, and survival and palliative care. With a focus on specific management decision-making, the book provides the basic information needed to guide the clinician on the ward or in the clinic, including clinical study references, medical comorbidity algorithms, and directed gynecologic cancer workups and treatments. In a bullet point format, the book provides the resources you need to meet the demands of clinical management in gynecologic cancer care.

Gynecologic Oncology Handbook features:

  • Covers all fundamentals of gynecologic oncology including, staging, surgical therapies, comorbidity diagnosis and management, adjuvant therapies, and background study data
  • Examines survivor care and palliative care practices
  • Includes clinical study references, medical comorbidity algorithms, and directed workups and treatments
  • Written in bullet-point format for quick reference

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Radiation Oncology: Difficult Cases and Practical Management 1st Edition

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Radiation Oncology provides residents, fellows, and clinicians with a practical, evidence-based guide to the current management of difficult cases in radiation oncology. Emphasis is on the management of those clinical challenges commonly seen in practice that the community practitioner would normally handle without outside referral. The book offers comparisons of treatment approaches to difficult situations, allowing the reader to compare their current treatment approach to that of experts and others in the community.

Radiation Oncology is organized in seven sections corresponding to the major treatment areas of radiation oncology. Each section includes three cases to illustrate specific clinical challenges for which there is no clear treatment protocol. The case discussion includes an expert opinion on optimal management along with alternatives from a second academic expert’s perspective and from a community practitioner’s perspective.

Radiation Oncology features:

  • Evidence-based approach to difficult management challenges in radiation oncology
  • Expert authors provide evidence assessment and management summaries through presentation of relevant cases
  • Community practitioner reviewers ensure real-world relevance of each discussion
  • Reviews the most relevant literature pertaining to the challenging scenarios clinicians encounter every day
  • Management alternatives allow discussion of the full range of management options and specifics for difficult problems including hardline recommendations

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The Truth in Small Doses: Why We’re Losing the War on Cancer-and How to Win It 1st Edition

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A provocative, eye-opening history of the war on cancer, The Truth in Small Doses asks why we are losing this essential fight and charts a path forward.

OVER THE PAST HALF CENTURY, deaths from heart disease, stroke, and so many other killers have fallen dramatically. But cancer continues to kill with abandon. In 2014, despite a four-decade “war” against the disease that has cost hundreds of billions of dollars, more than 1.6 million Americans will be diagnosed with cancer and nearly six hundred thousand will die from it.

A decade ago, Clifton Leaf, a celebrated journalist and a cancer survivor himself, began to investigate why we had made such limited progress fighting this terrifying disease. The result is a gripping narrative that reveals why the public’s immense investment in research has been badly misspent, why scientists seldom collaborate and share their data, why new drugs are so expensive yet routinely fail, and why our best hope for progress–brilliant young scientists– are now abandoning the search for a cure. The Truth in Small Doses is that rare tale that will both outrage readers and inspire conversation and change.

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Prostate Cancer and the Man You Love: Supporting and Caring for Your Partner 1st Edition

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Prostate cancer is the most commonly diagnosed cancer in men after skin cancer. However this cancer is highly curable and most men live for many years after treatment; only eleven percent of cancer deaths are due to prostate cancer. It is well known that the side effects of the treatment cause more suffering than the disease itself. Side effects of surgery include incontinence and erectile difficulties; radiation therapy leads to urinary and bowel problems; and androgen deprivation (hormone) therapy leads to a broad range of long-term side effects affecting physical and emotional functioning.

But it is not only the man who suffers through treatment and its side effects. The partners and spouses of prostate cancer survivors are known to experience distress as the man they love moves through the various stages of diagnosis, treatment, and survival. While prostate cancer is a couples’ disease, there is much attention paid to the man with cancer and very little to the person and his partner or spouse, who is his prime supporter and who often struggles to make sense of what has happened and why, and how best to support and take care of him.

Prostate Cancer and the Man You Love speaks to the loving partners/spouses of men with prostate cancer, whether soon after diagnosis, or later when the man gets on with the rest of his life. Katz includes both the medical information necessary to understanding the disease and firsthand accounts from cancer patients and survivors and their partners. Tips for communication and problem solving, with both partners and health care teams, are offered throughout. Anyone dealing with prostate cancer will find in these pages comfort and insight, as well as specific advice for coping, healing, and moving forward in the spirit of healing and love.

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