Atlas of Sexually Transmitted Diseases: Clinical Aspects and Differential Diagnosis 1st ed. 2018 Edition

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About the Author

Sphingosine-1-Phosphate Signaling in Immunology and Infectious Diseases (Current Topics in Microbiology and Immunology)

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About the Author

Infections in the Adult Intensive Care Unit

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From the Back Cover

Human Respiratory Viral Infections 1st Edition

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Using a multidisciplinary approach, Human Respiratory Viral Infections is set at the level between the definitive reference work and an essential clinical manual. Exploring recent advances in human respiratory viral research, the text builds on the basic sciences of epidemiology, virology, molecular biology, and immunology to cover clinical diagnosis, mechanism of pathogenesis, manifestations of disease, impact, treatment, and management strategies.

  • Provides a comprehensive review of all the major human respiratory viral infections
  • Supplies a detailed description of the anatomy of the respiratory system
  • Discusses the salient features of specific viruses
  • Examines the latest diagnostic tools
  • Covers risk factors associated with incidence of respiratory viral infections in children and adults in different occupational and environmental settings

Presenting the latest knowledge in human respiratory viral infections, this text will be immensely valuable for pulmonologists, biomedical scientists, research scholars, virologists, vaccinologists, immunologists, clinicians, pharmacologists, and public health specialists.

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Management of Periprosthetic Joint Infection: A global perspective on diagnosis, treatment options, prevention strategies and their economic impact 1st ed. 2018 Edition

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Periprosthetic joint infection (PJI) is among the most serious complications in the field of endoprosthetics. The number of PJIs is increasing worldwide and poses a real interdisciplinary challenge for everyone involved. For the patient concerned, it is necessary to promptly work out an adequate therapy solution to fight off the infection. Both the clinical experience of the surgeon and the proper diagnostic processes are prerequisite for the reliable detection and identification of an infection. The microbiologist is responsible for identifying the causative germs by screening the patient’s synovial fluid and tissue samples. Based on the findings and subsequent resistance testing, the infectious disease specialist can recommend the appropriate antibiotic therapy. Furthermore, the clinical pharmacist is consulted regularly throughout the therapy to discuss the risk of potential drug interactions. The surgeon will proceed with the revision surgery, following defined algorithms. Adequate radical debridement of infected and necrotic surrounding tissue is the most important step towards a successful cure of the infection. Accompanying the surgery, anti-infective agents are given systemically and locally. While systemic application of anti-infectives mainly reduces the number of haematogenic-spreading planktonic germs, local application immediately forms a colonization barrier and protects the implant from sessile biofilm formation. Concurrently, antibiotics are actively released from the implant, resulting in local germ reduction. Thus, local agents are embedded in the concept of surgical PJI treatment as a reliable adjuvant measure and they sustainably support the successful outcome. In one-stage procedures, local agents are released from specialized antibiotic-loaded bone cements, while in two- or multi-stage procedures, local agents are released from corresponding temporary spacers (interim prostheses). Even from an economic standpoint, the combination of systemic and local agent application is meaningful. Furthermore, there are some interesting trends towards the coating of metallic implants to protect against biofilm formation on the implant surface.

On the basis of their personal experience, specialists from all over the world present, explain and discuss preventive approaches, appropriate diagnostic strategies for detection, reproducible effective surgical treatments  as well as the economic impact of PJI. The reader can use this book as a solid platform for comparing their own approach to PJI treatment with the specialists’ recommendations.

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Population Mobility and Infectious Disease

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Population Mobility and Infectious Disease moves beyond traditional behavioral and demographic theories of disease diffusion to focus on larger issues of social ecology and public health. With depth rarely seen in the international literature, it explores the complex and varied roles of mobile, transient, and displaced populations in the worldwide spread of airborne, waterborne, and sexually transmitted infections.

The book argues that while biomedical events cause disease, social forces such as poverty and marginalization magnify them by giving them new opportunities to take hold. Population mobility―either voluntary or forced―brings contact between populations with different disease prevalence rates; outbreaks in turn are compounded by inequalities in access to medical care. From Katrina to Darfur, and from influenza to AIDS, an expert panel of health and social scientists bring the socioeconomic context of epidemics into clear focus.

-Historical perspectives on migration, development, and epidemics

-Social resources and health barriers among migrant groups

-The role of mobile labor populations (e.g., migrant workers, truckers, the military) in disease transmission

-War, refugees, resettlement: health effects on the world scale

-Natural disasters and climate change: their local and global disease impact

-Leisure travel and health risks, from spring-break binges to commercial sex tourism

-Methodological and design issues confronting researchers

-The politics of prevention: ethical concerns in migration-related illness

The unique scope of this book makes it as timely as the next health crisis and relevant to a gamut of interrelated fields, including public and international health, epidemiology, psychology, sociology, anthropology, human rights, and development and planning. By expanding concepts, examining trends, and pinpointing areas for intervention, it is a critical resource for the academic, research, practice, and policy sectors.

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The AIDS Pandemic: Searching for a Global Response 1st ed. 2018 Edition

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This ambitious book provides a comprehensive history of the World Health Organization (WHO) Global Programme on AIDS (GPA), using it as a unique lens to trace the global response to the AIDS pandemic. The authors describe how WHO came initially to assume leadership of the global response, relate the strategies and approaches WHO employed over the years, and expound on the factors that led to the Programme’s demise and subsequent formation of the Joint United Nations Programme on HIV/AIDS (UNAIDS). The authors examine the global impact of this momentous transition, portray the current status of the global response to AIDS, and explore the precarious situation that WHO finds itself in today as a lead United Nations agency in global health.

Several aspects of the global response – the strategies adopted, the roads taken and not taken, and the lessons learned – can provide helpful guidance to the global health community as it continues tackling the AIDS pandemic and confronts future global pandemics.

Included in the coverage:

·The response before the global response

·Building and coordinating a multi-sectoral response

·Containing the global spread of HIV

·Addressing stigma, discrimination, and human rights

·Rethinking global AIDS governance

·UNAIDS: finding its place in congested waters

The AIDS Pandemic will find an engaged audience among policymakers, students, faculty, journalists, researchers, and other health professionals working and interested in global health, public health, the World Health Organization, HIV/AIDS, global pandemics, the history of medicine, and global health policy. It will also interest those involved in international relations, international development, global affairs and governance, the United Nations, and NGOs.

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Sexually Transmitted Infections: Nursing Care and Management

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This new book has been written to reflect the needs of students and practitioners in this field, where the role of the nurse is extended. Previously fragmented information is now gathered together in one comprehensive volume for lecturers and specialist nurses in GU Medicine. It is also a source of reference in adult nursing, practice nursing, midwifery and family planning as sexually transmitted infections are relevant to all nurses.

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Infectious Change: Reinventing Chinese Public Health After an Epidemic 1st Edition

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In February 2003, a Chinese physician crossed the border between mainland China and Hong Kong, spreading Severe Acute Respiratory Syndrome (SARS)―a novel flu-like virus―to over a dozen international hotel guests. SARS went on to kill about 800 people and sicken 8,000 worldwide. By July 2003 the disease had disappeared, but it left an indelible change on public health in China. The Chinese public health system, once famous for its grassroots, low-technology approach, was transformed into a globally-oriented, research-based, scientific endeavor.

In Infectious Change, Katherine A. Mason investigates local Chinese public health institutions in Southeastern China, examining how the outbreak of SARS re-imagined public health as a professionalized, biomedicalized, and technological machine―one that frequently failed to serve the Chinese people. Mason recounts the rapid transformation as young, highly-trained biomedical scientists flooded into local public health institutions, replacing bureaucratic government inspectors who had dominated the field for decades. Infectious Change grapples with how public health in China was reinvented into a prestigious profession in which global impact and recognition were paramount―and service to vulnerable local communities was secondary.

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Viruses, Genes, and Cancer (Current Topics in Microbiology and Immunology) 1st ed. 2017 Edition

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This volume focuses on virus-host cell interactions, cellular genes acquired or modulated by viruses, the pathological effects of these interactions, and therapeutic interventions. Several chapters specifically address the role of viruses and genes – such as oncogenes, proto-oncogenes, or tumor suppressor genes – in the etiology of human cancer. Oncogenic signaling by PI3 kinase, mTOR, Akt, or the major cancer drivers MYC and RAF, and the role of tumor suppressors like p53, are discussed in detail. The volume also explores the emerging role of noncoding RNAs such as microRNAs in tumorigenesis and cancer therapeutics, and offers new insights into the role of HIV-host interactions relevant to pathogenesis and treatment. Gathering contributions written by leading scientists in their respective fields, the volume offers a valuable resource for researchers and clinicians alike.

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