Gastric Cancer In The Precision Medicine Era: Diagnosis and Therapy

Gastric Cancer In The Precision Medicine Era: Diagnosis and Therapy

Gastric Cancer In The Precision Medicine Era: Diagnosis and Therapy

Gastric cancer is one of the most common and potentially lethal gastrointestinal malignancy, but it is now at the forefront of modern oncology due to new discoveries.  In recent years, the field of gastric cancer has been transformed by many notable developments in both the diagnostic area and the therapeutic strategies.
The main aim of the text is to propose a comprehensive, state-of-the art review of this field, and will serve as a valuable resource for oncologists, pathologists, surgeons and researchers with an interest in gastric cancer.  The first chapters will review the interplay between pathogens and especially H. pylori, inflammation, genomic instability, and tumorigenesis. Secondly, an exhaustive overview of the diagnosis of gastric cancer from a clinical/endoscopic and pathologic perspectives will be illustrated. Two specific chapters will deal with tissue and serum biomarkers with an important role in diagnosis as well as prognostic and predictive markers of response to specific therapy. A central section of the book will focus on treatment options available today for patients. Surgery is the cornerstone of treatment for gastric cancer; however, the prognosis of patients with locally advanced disease is still poor even after curative resection. Therefore, in order to improve the prognosis of patients, especially with advanced stage, a multimodal strategy is advisable and is thoroughly addressed in the appropriate section.
With the advent of next-generation sequencing and new preclinical model technologies, the genomic landscape of gastric cancer  has been delineated and  molecular characterizations finalized to novel therapeutic targets of each molecular subtype have been identified.  These advances are making it feasible to integrate clinical and phenotype-based diagnostic and therapeutic methods and are described in a dedicated section.  The text will conclude with chapters focusing on the future direction of gastric cancer research in the precision medicine era: an in-depth analysis of non-coding RNAs and their role in gastric cancer, the impact of  immunomodulation/immunotherapy and the perspectives of nano-medicine will be finally proposed to the audience. A brief review of the existing literature addressing the above mentioned topics will be present in each chapter.

 

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Office-Based Maxillofacial Surgical Procedures: A Step-by-step Approach

Office-Based Maxillofacial Surgical Procedures: A Step-by-step Approach

Office-Based Maxillofacial Surgical Procedures: A Step-by-step Approach

This book is a comprehensive, step-by-step guide to maxillofacial surgical procedures typically performed in an office setting. It comprises three sections, the first of which provides an overview of general and basic perioperative topics such as medical and facial assessment, laboratory indications, local anesthesia, and oral and parenteral sedation.  In the second section, a wide range of dentoalveolar procedures are described in detail. The final section is devoted to maxillofacial cosmetic procedures. Here, readers will find stepwise guidance on scar revision, chemical peel, laser resurfacing, dermabrasion, use of neuromodulators and fillers, neck procedures, blepharoplasty, and hair transplant surgery. The book is written by acknowledged experts and is multi-institutional and multispecialty based. It will meet the needs of multiple surgical professionals, including oral and maxillofacial surgeons, plastic surgeons, otolaryngologists, cosmetic surgeons, dentists, and medical and dental students. Health care providers will also be able to use the book as a resource to expand their knowledge on common maxillofacial surgical procedures.

 

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Holcomb and Ashcraft’s Pediatric Surgery 7th Edition

Holcomb and Ashcraft’s Pediatric Surgery 7th Edition

Holcomb and Ashcraft’s Pediatric Surgery 7th Edition

Known for its readability, portability, and global perspectivesHolcomb and Ashcraft’s Pediatric Surgery remains the most comprehensive, up-to-date, single-volume text in its field. As technology and techniques continue to evolve, the 7th Edition provides state-of-the-art coverage-both in print and on video-of the full range of general surgical and urological problems in infants, children, and adolescents, equipping you to achieve optimal outcomes for every patient.

Provides authoritative, practical coverage to help you implement today’s best evidence-based open and minimally invasive techniques, with guidance from internationally recognized experts in the field.

Features more than 1,000 high-quality images depicting the visual nuances of surgery for the full range of pediatric and urologic conditions you’re likely to see.

Delivers comprehensive updates throughout including the latest advances in managing Inguinal Hernias and Hydroceles; Imperforate Anus and Cloacal Malformations; Hirschsprung Disease; Duodenal and Intestinal Atresia and Stenosis; Esophageal Atresia; and more.

Offers access to more than 50 videos that help you improve and refine your surgical skills. New videos cover Fetal Endoluminal Tracheal Occlusion (FETO); Laparoscopic Inguinal Hernia Repair; Robotic Extravesical Ureteral Reimplantation; Laparoscopic Management of Ovarian Torsion; and Laparoscopic Sleeve Gastrectomy.

 

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Ashcraft’s Pediatric Surgery (Expert Consult Title) 6th Edition

Ashcraft’s Pediatric Surgery (Expert Consult Title) 6th Edition

Ashcraft’s Pediatric Surgery (Expert Consult Title) 6th Edition

Acclaimed for its unsurpassed readability and manageable scope, Ashcraft’s Pediatric Surgery presents authoritative, practical guidance on treating the entire range of general surgical and urological problems in infants, children, and adolescents. State-of-the-art, expert coverage equips you to implement all the latest approaches and achieve optimal outcomes for all of your patients.

Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability.

Make the most effective use of today’s best open and minimally invasive techniques, including single-site umbilical laparoscopic surgery, with guidance from internationally recognized experts in the field.

Focus on evidence-based treatments and outcomes to apply today’s best practices.

Stay current with timely topics thanks to brand-new chapters on Choledochal Cyst and Gallbladder Disease, Tissue Engineering, and Ethics in Pediatric Surgery, plus comprehensive updates throughout.

Hone and expand your surgical skills by watching videos of minimally invasive procedures for recto urethral fistula, biliary atresia, laparoscopic splenectomy, uterine horn, and more.

Grasp the visual nuances of surgery from over 1,000 images depicting today’s best surgical practices.

 

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Operative Pediatric Surgery 2nd Edition

Operative Pediatric Surgery 2nd Edition

Operative Pediatric Surgery 2nd Edition

Operative Pediatric Surgery, Second Edition is a comprehensive, well-illustrated text that delivers expert coverage of the pathophysiology, diagnosis, and treatment of pediatric surgical disease. This detailed single-volume resource is enhanced by numerous drawings, radiographs, and photographs that illustrate the authors’ preferred operative techniques. Wherever appropriate, diagnostic and care guidelines are also included.

Operative Pediatric Surgery, Second Edition is divided into 11 sections that include a total of 100 chapters. The book opens with an informative General Principles section that provides important background information on topics such as the history of pediatric surgery, ethical considerations, pediatric surgical critical care, and office-based ambulatory surgery. The rest of the text is organized primarily by organ, enhanced by a timely section on solid organ transplantation.

In this Second Edition, each chapter author has thoroughly updated and refreshed their topic, and in many instances, minimally invasive operative techniques are included with open approaches. There are also exciting new chapters on:

  • Hypospadias
  • Vesicoureteral reflux
  • Non-rhabdomyosarcoma soft tissue sarcomas
  • Gastrointestinal polyps and cancer
  • Adolescent bariatric surgery

Operative Pediatric Surgery will prove to be an essential reference for pediatric surgeons seeking optimal diagnosis and treatment approaches for their patients.

 

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Foundations of Operative Surgery: An Introduction to Surgical Techniques

Foundations of Operative Surgery: An Introduction to Surgical Techniques

Foundations of Operative Surgery: An Introduction to Surgical Techniques

Technical expertise in the operating theatre remains a hallmark of surgical practice. Theatre etiquette and instrument handling skills are highly specific to the specialty of surgery, and trainees need to quickly become familiar with them.

This book introduces operative technique in an original way. It first discusses the roles and responsibilities of the surgical trainee and explains some the unwritten rules of behaviour in the operating theatre. It then brings a unique approach to teaching operative surgery by describing operations as a series of generic manoeuvres which, when mastered and put together in the correct order, will allow any procedure to be performed – and prove useful across subspecialty boundaries.

This approach is illustrated using clear diagrams and full color photographs. It is further enhanced through a free DVD comprising 55 high quality video clips taken from live operating sessions which illustrate the various techniques described inside.

 

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Textbook of Surgery 4th Edition

Textbook of Surgery 4th Edition

Textbook of Surgery 4th Edition

Medical students and trainee surgeons must understand both essential surgical principles and new developments in science and technology to perform basic procedures as part of a multidisciplinary healthcare team.Textbook of Surgery is a comprehensive review of general and specialty surgery, including cardiothoracic surgery, neurosurgery, plastic surgery, ophthalmology, orthopaedic surgery, and vascular surgery. Emphasizing practical and problem-solving skills, this core textbook of surgical curricula outlines surgical assessment and treatment, examines a variety of surgical disorders, and presents an applied approach to the diagnosis and management of common surgical conditions. Specialist chapters covering topics such as transplantation surgery, surgical oncology, anaesthesia and pain medication, bariatric surgery, and post-operative management are written by leading experts in their respective fields.

Now in its fourth edition, this indispensable textbook includes new and revised coverage of surgical risk assessment, surgical wound management, emergency general surgery, lower gastrointestinal surgery, endovascular therapies, and an introduction to the operating theatre. All chapters are fully updated to reflect current best practices and surgical guidelines, making this volume perfect for medical students and junior doctors on surgical attachments, as well as an ideal reference for RACS and MRCS candidates.

 

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Pediatric Hepatology and Liver Transplantation

Pediatric Hepatology and Liver Transplantation

Pediatric Hepatology and Liver Transplantation

This book is the first to provide balanced examination of both pediatric liver disease and liver transplantation – two topics that are inherently related, given that most chronic liver disorders eventually require organ replacement. The different forms of liver disease encountered in the pediatric age group are first discussed in a series of disease-specific chapters that have a reader-friendly, uniform structure covering pathophysiology, diagnostic and treatment algorithms, clinical cases, and transition to adult care. Key topics in the field of liver transplantation are then addressed. Examples include indications and contraindications, surgical techniques and complications, immunosuppression, in pediatric liver transplantation, acute and chronic rejection and allograft dysfunction, and CMV and EBV infection in transplant recipients, long-term graft injury and tolerance. A section on pediatric hepatology across the world includes chapters presenting the features and management of pediatric liver disease in South-America, Africa and Asia. A closing section considers what the future holds for pediatric liver disease and its management, including novel genetic testing, cell therapy and gene therapy. Pediatric Hepatology and Liver Transplantation will be of value for a range of practitioners, from residents making their first approach to pediatric liver disease through to specialists working in transplantation centers.

 

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Ferraro’s Fundamentals of Maxillofacial Surgery 2nd ed

Ferraro’s Fundamentals of Maxillofacial Surgery 2nd ed

Ferraro’s Fundamentals of Maxillofacial Surgery 2nd ed

Ferraro’s Fundamentals of Maxillofacial Surgery is the newly revised and updated second edition of the text originally edited by James W. Ferraro. Written for trainees and students as well as experts in oral and maxillofacial surgery, and experts in related subspecialties such as otolaryngology and plastic surgery, this highly illustrated text is an invaluable source of hands-on, practical knowledge for those taking the ASMS Basic Course, or for any specialist seeking a comprehensive review of maxillofacial surgery.

 

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