Category: Gastroenterology/Hepatology

Liver Transplantation and Hepatobiliary Surgery: Interplay of Technical and Theoretical Aspects

Liver Transplantation and Hepatobiliary Surgery: Interplay of Technical and Theoretical Aspects

Liver Transplantation and Hepatobiliary Surgery

In the past, liver resections and liver transplantations were performed by different surgical teams, with very little interplay between the two. However, the evolution toward more complex operations called for an increasingly intense interaction between these surgical techniques: split liver and living donor liver transplantation have become popular in the transplant community, utilizing the Coinaud segmental anatomy in a very sophisticated way, while portal and arterial resection and reconstruction have become indispensable methods for treating Klatskin tumors infiltrating the hepatic hilum.  This book offers a complete overview of the connections between liver transplantation and hepatobiliary surgery. It focuses on ex situ techniques for resection of tumors at the suprahepatic confluence, with or without venous reconstruction, and on total vascular exclusion of the liver with the aid of a venovenous bypass that should be a surgical option for referral centers in hepatopancreatobiliary surgery. By taking into consideration the development of minimally invasive liver surgery, it will introduce readers to a variety of new perspectives such as: vascular exclusion techniques with or without extracorporeal circulation, hemodynamic implications and lessons learned from liver transplant surgery, and technical details on pediatric transplantation and its informative role in modern biliary tract surgery.

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Budd-Chiari Syndrome

Budd-Chiari Syndrome

Budd-Chiari Syndrome

This book offers a systematic introduction to Budd-Chiari syndrome, a rare but life-threatening vascular disorder of the liver, which refers to obstructions at any site from the hepatic veins to the suprahepatic inferior vena cava. The book mainly covers the history, epidemiology, etiology and risk factors, pathology, diagnosis, pharmacological and interventional aspects, surgical treatment, etiological treatment, and prognostic assessment of Budd-Chiari syndrome. Notably, it also presents cutting-edge research findings in this field. The early diagnosis of Budd-Chiari syndrome is vital, as it allows clinicians to pursue more targeted and effective treatment strategies, thus improving patient outcomes. However, much information, including the latest advances, has not yet been fully disseminated in current clinical practice. This book addresses that gap, helping physicians to improve diagnosis and establish standard treatment strategies, helping researchers conduct clinical and experimental studies, and even helping patients and their relatives to recognize this disease.

 

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Liver Diseases: A Multidisciplinary Textbook

Liver Diseases: A Multidisciplinary Textbook

Liver Diseases: A Multidisciplinary Textbook

This book provides an in-depth coverage not only of liver pathology but also of diagnosis of the numerous types of liver disease, placing specific emphasis on current treatments of liver pathology including the most up-to-date information on liver transplantation.

The first part of provides an in-depth account of the liver pathology in different conditions such as Hepatits, liver ischaemia reperfusion injury, Lyme disease, cirrhotic cardiomyopathy and hepatocellular carcinoma. The second part provides a comprehensive overview of diagnostic methods. Of particular interest are chapters on the latest techniques in Patient-specific 3D printing and transient elastography (FibroScan). The final part focuses on treatment and provides a step-by step guide to the therapeutic management of liver diseases starting with pharmacological treatment and techniques including surgery and liver transplantation.

This is an invaluable book  for clinicians, practitioners including academics, scientists/researchers and postgraduates to provide the newest knowledge in the field of liver pathogenesis. It is written by a multidisciplinary team of experts in hepathology, gastroenterology, and surgery especially from liver transplantation.

 

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HIV Transmission: Statistical Modelling

HIV Transmission: Statistical Modelling

HIV Transmission: Statistical Modelling

This book presents models describing HIV transmission rates at population level, discussing the main statistical methods and analytical interventions. It also assesses the practical applicability of the various modelling techniques, offering readers insights into what methods are available and, more importantly, when they should be used to address HIV transmission at global level. The book includes realistic simulation models fitted to clarify the rate of HIV mother-to-child transmission (HIV MTCT), and substantiates the conclusions that can be drawn as well as the appropriate time for making global-level clinical decisions concerning people living with HIV/AIDS (PLHIVs). Intended for students, academics and researchers, the book offers more than just an introduction to the topic – it also features in-depth, yet easy-to-understand, descriptions of a new mathematical/statistical HIV mother-to-child transmission model, making it a useful resource for clinicians, public health workers and policymakers involved in implementing HIV-prevention programmes at national /global level.

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Portal Hypertension: Imaging, Diagnosis, and Endovascular Management 3rd Edition

Portal Hypertension: Imaging, Diagnosis, and Endovascular Management 3rd Edition

Portal Hypertension: Imaging, Diagnosis, and Endovascular Management 3rd Edition

Previously published by the Society for Interventional Radiology (SIR), this fully revised and updated third edition of Portal Hypertension: Imaging, Diagnosis, and Endovascular Management is the first volume in collaboration between Thieme and the SIR. Edited by Wael Saad and written by internationally recognized experts, this authoritative volume is a comprehensive guide to the diagnosis and interventional management of portal hypertension. A potentially serious condition, portal hypertension presents considerable clinical challenges due to the delicate nature of the impacted organs, veins, and vessels.

From pathophysiology to the latest state-of-the-art approaches, five major sections encompass diagnostic, medical, endoscopic, non-vascular, surgical, percutaneous, endovascular, and balloon-occluded methodologies, including indications, complications, and clinical trial results. Throughout this book’s 33 chapters, a Who’s Who of world-renowned interventional radiologists share clinical pearls and step-by-step procedural guidance.

Several techniques have undergone significant advances since the second edition was published, including Transjugular Intrahepatic Portosystemic Shunt (TIPS), Balloon-Occluded Retrograde Transvenous Obliteration (BRTO), Balloon-Occluded Antegrade Transvenous Obliteration (BATO), and variations on TIPS, and all these are featured herein.

Key Highlights

  • Hepatic and portal venous anatomy relative to procedural approaches
  • Nearly 250 figures elucidate anatomical structures and technical methodologies
  • TIPS: patient selection, effects on kidney and liver function, hemodynamic changes, intravascular ultrasound guidance, Doppler surveillance, and utilization for Budd-Chiari Syndrome and liver transplantation
  • TIPS clinical study outcomes for variceal bleeding, ascites, and hydrothorax
  • BRTO and BATO techniques, clinical study outcomes, and utilization for gastric varices
  • Management of mesenteric and portal vein stenosis, thrombosis, and hypersplenism

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Ascites: Physiopathology, Treatment, Complications and Prognosis

Ascites: Physiopathology, Treatment, Complications and Prognosis

Ascites: Physiopathology, Treatment, Complications and Prognosis

In this book, the authors describe the physiopathology of the diverse causes of ascites,the types of treatments recommended, the recent advances achieved, the complications and the prognosis of the different clinical situations that doctors must face.

The term “ascites” is from the Greek word askites meaning “baglike.” Although most commonly due to cirrhosis, severe liver disease or metastatic cancer, its presence can be a sign of other significant medical problems, such as Budd-Chiari syndrome. Diagnosis of the cause is usually done with blood tests, an ultrasound scan of the abdomen, and direct removal of the fluid by a needle or paracentesis (which may also be therapeutic). Treatment using medications (diuretics), external drainage, or other treatments is clearly defined.

 

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Critical Care for Potential Liver Transplant Candidates

Critical Care for Potential Liver Transplant Candidates 

Critical Care for Potential Liver Transplant Candidates

This book focuses on patients with end-stage-liver disease (ESLD) who could possibly qualify for liver transplant. This patient cohort raises many problems: who should be treated and also, when is it too late for transplant? The authors are all dedicated experts in the field of ESLD/liver transplantation, but from different disciplines with different views of the problem. In the past 15 years many things have changed in the treatment for these patients: cardiac assessment, treatment of porto-pulmonary hypertension, hemodynamics, coagulation assessment and management, diagnosis of kidney failure, and the timing of dialysis. These issues are comprehensively discussed in this book, in order to provide physicians starting in the field of transplantation an overview of different areas of concern.

 

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Endoscopic Treatment Strategy for Upper GI Tract Neoplasms

Endoscopic Treatment Strategy for Upper GI Tract Neoplasms

Endoscopic Treatment Strategy for Upper GI Tract Neoplasms

This book presents various cases of upper GI tract neoplasms, discussing endoscopic diagnostic procedures and treatment strategies, such as white light endoscopy (WLE ), magnified endoscopy with narrow band imaging (NBI) and endoscopic ultrasonography (EUS). Focusing on the esophagus, stomach and duodenum, it provides user-friendly, practical information on these innovative approaches, and explores treatments, pathological insights, including target biopsy, and therapies for specific cases.

Endoscopic Treatment Strategy for Upper GI Tract Neoplasms appeals to a wide readership, from trainees to experienced gastroenterologists. It presents research evidence to broaden readers’ understanding and enable them to optimize outcomes for patients.

 

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The SAGES Manual of Flexible Endoscopy

The SAGES Manual of Flexible Endoscopy

The SAGES Manual of Flexible Endoscopy

This book addresses all aspects of endoscopy from scope and tower basics to the more advanced interventional procedures like endoscopic retrograde cholangiopancreatography, per-oral esophageal myotomy, and percutaneous endoscopic gastrostomy. It covers a broad range of topics in order to remain relevant to the surgical subspecialist, the community general surgeon, the surgical fellow interested in endolumenal and transluminal procedures, and the surgical resident interested in the very basics of endoscopy. The table of contents is intentionally designed to mirror the Flexible Endoscopy curriculum currently being implemented for all minimally invasive, advanced GI and surgical endoscopy fellowships. The chapters are broken up into five parts. The first part introduces the SAGES Masters Program, followed by parts that cover flexible endoscopy basics, flexible endoscopy procedures, and finally bariatric flexible endoscopy. Written by experts and thought leaders in their fields, The SAGES Manual of Flexible Endoscopy serves as a valuable resource for surgeons of all training and skill levels to better grasp an overview of modern endoscopy practice.

 

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Molecular Genetics of Inflammatory Bowel Disease 2nd ed

Molecular Genetics of Inflammatory Bowel Disease 2nd ed

Molecular Genetics of Inflammatory Bowel Disease 2nd ed

This book reaches out to a wide variety of professionals in the biomedical field with an interest in inflammatory bowel disease (IBD). Enormous progress has been made in the last few years since the publication of the first edition in the study of complex diseases and IBD, with hundreds of genomic regions identified that are associated with increased risk. Authored by leading clinical and research scientists in the field, the book includes state-of-the art synopses of recent genetic findings, and their interpretation for current and future exploitation in translational approaches to personalized medicine in IBD. The book also covers risk prediction, improved diagnostic and therapeutic precision, dissection of disease phenotypes and subtypes, identification of biomarkers, and host gene-microbiota interactions of clinical relevance.

 

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