Dermal Replacements in General, Burn, and Plastic Surgery: Tissue Engineering in Clinical Practice

“This is an overview of clinical and engineering options for skin reconstruction and replacement. … General and plastic surgeons with a particular interest in burns or complex soft tissue infections are an appropriate audience for this work … . Chapters are clearly written with generous reference lists citing primary literature dating to within two to three years of publication. … This book provides an international perspective on the horizons and future options for management of important clinical problems.” (David J. Dries, Doody’s Book Reviews, October, 2013)

The skin is the largest human organ system. Loss of skin integrity due to injury or illness results in a substantial physiologic imbalance and ultimately in severe disability or death. The most common cause of significant skin loss is thermal injury, followed by trauma and chronic ulcerations.

Over the past decades extraordinary advances have been made in the understanding of cellular and molecular processes of wound healing and the pathobiology of chronic wounds. This knowledge has led to wound care innovations that facilitate more rapid closure of wounds with better functional and aesthetic outcome.  A sensible and resource-saving utilization of these innovative technologies requires a broad knowledge of these processes and innovations.

This book intends to give an overview about today’s wound care developments in tissue engineering and skin replacement. It presents a variety of indications and diversities of clinical applications to help the surgeon select a specific procedure for each clinical situation.

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