Complete Guide to Prescription & Nonprescription Drugs 2018-2019

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The classic guide to all major prescription and nonprescription drugs, featuring revised, up-to-date FDA information and an A–Z list of illnesses for easy reference. Includes coverage of dosage and length of time before a drug takes effect; side effects; special precautions; interactions with other food and drugs; standards for use by different age groups; and more.

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Drugs of Abuse, A DEA Resource Guide: 2017 Edition

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Education plays a critical role in preventing substance abuse. Drugs of Abuse, A DEA Resource Guide, is designed to be a reliable resource on the most commonly abused and misused drugs in the United States. This comprehensive guide provides important information about the harms and consequences of drug use by describing a drug’s effects on the body and mind, overdose potential, origin, legal status, and other key facts.

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Heparin – A Century of Progress (Handbook of Experimental Pharmacology)

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Heparins remain amongst the most commonly used drugs in clinical practice.  Almost 100 years have passed since the initial discovery of this complex substance and, during this time, understanding of the nature and uses of heparin and related molecules has grown dramatically. The aim of this volume is to summarise the developments that have led to the current status of both heparins as drugs and the field of heparin research, with a focus on the particularly rapid progress that has been made over the past three decades. Individual sections are dedicated to the nature of heparin as a biological molecule, the current approaches and techniques that are used to ensure the safety and reliability of heparin as a medicine, the clinical pharmacology of heparin as an anticoagulant drug, effects and potential applications of heparin aside of those involving haemostasis and, finally, the nature and potential uses of heparin-like materials from both natural and synthetic sources.

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Percutaneous Penetration Enhancers Chemical Methods in Penetration Enhancement: Modification of the Stratum Corneum 1st ed

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Percutaneous Penetration Enhancers in a mini-series format comprising five volumes, represents the most comprehensive reference on enhancement methods – both well established and recently introduced – in the field of dermal/transdermal drug delivery. In detail the broad range of both chemical and physical methods used to enhance the skin delivery of drugs is described. All aspects of drug delivery and measurement of penetration are covered and the latest findings are provided on skin structure and function, mathematics in skin permeation and modern analytical techniques adapted to assess and measure penetration. In offering a detailed description of the methods currently in use for penetration enhancement, this book will be of value for researchers, pharmaceutical scientists, practitioners and also students.

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Pharmacotherapy Principles and Practice, Third Edition (Chisholm-Burns, Pharmacotherapy) 3rd Edition

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Learn the essential principles of pharmacotherapy and how they apply to today’s healthcare

Pharmacotherapy Principles & Practice, Third Edition uses a solid evidence-based approach to teach you how to design, implement, monitor, and evaluate medication therapy. This trusted text provides everything you need to gain an in-depth understanding of the principles essential to the optimal pharmacotherapy of disease. In order to be as clinically relevant as possible, the disease states and treatments discussed focus on disorders most often seen in clinical practice. Chapters were written or reviewed by pharmacists, nurse practitioners, physician assistants, and physicians who are authorities in their fields.

The book opens with an introductory chapter followed by chapters on pediatrics, geriatrics, and palliative care. The remainder of the text consists of ninety-eight disease-based chapters that review etiology, epidemiology, pathophysiology, and clinical presentation, followed by therapeutic recommendations for drug selection, dosing, and patient monitoring.

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Non-Pharmacological Management of Osteoporosis: Exercise, Nutrition, Fall and Fracture Prevention 1st ed

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This practical guide presents the most up-to-date information on the application of non-pharmacological and physical therapeutic measures, either used independently or in combination with pharmacotherapy, for the management of osteoporosis. Pharmacotherapy remains the primary treatment for osteoporosis, but to improve the biomechanical competence of bone and improve quality of life, there needs to be more comprehensive management approach involving non-pharmacological methods. The book opens with a discussion of the diagnosis, pathophysiology, complications and consequences of osteoporosis. Exercise, nutrition, orthotics, and other rehabilitation measures such as whole body vibration and electrical muscle stimulation, each described in details in chapters of their own, have had a beneficial impact on fall and fracture prevention as well as recovery post-fracture. In addition, the application of acupuncture for pain management and movement-based mind-body therapies like tai chi and the Feldenkrais method are explored.

Providing a description of independent and adjuvant techniques and practices for treatment and improving quality of life, Non-Pharmacological Management of Osteoporosis is an excellent resource for endocrinologists, bone specialists, physical therapists, occupational therapists and all clinical practitioners and staff working with osteoporosis patients.

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Pharmacology and Pathophysiology of the Control of Breathing (Lung Biology in Health and Disease)

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Exploring the functional anatomy and physiology of the ventilatory control system from the intracellular to the integrative level, this references serves as the first source to offer comprehensive coverage of the influences of various pharmacological agents on the control of breathing.

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Gamma-Hydroxybutyrate: Molecular,Functional and Clinical Aspects

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Gamma-hydroxybutyrate (GHB) has come a long way since early experiments in animals where it was found to induce a sleep-like state and from its use in general anaesthesia in human subjects. It has been found to be a naturally-occurring compound in the brain, a metabolite of GABA, the emerging ubiquitous inhibitory neurotransmitter. This has opened up a completely new line of research in an effort to establish a function for GHB.

Gamma-Hydroxybutyrate: Pharmacological and Functional Aspects has brought together the combined expertise of many of the leading authorities on the biochemistry, physiology and pharmacology of GHB in the central nervous system. Each chapter is an in-depth review of the field and the book itself will appeal to all neurobiologists interested in neurotransmitter mechanisms, as well as to clinicians and other health-care workers interested in this fascinating chemical.

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The New Drug Reimbursement Game: A Regulator’s Guide to Playing and Winning 2015th Edition

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From the Back Cover

This comprehensive text presents a rigorous framework from within which regulators can respond strategically to the claim by the pharmaceutical industry that lower drug prices today lead to a loss for the population’s future health due to less innovation. It starts with a critical review of the empirical evidence of the return to consumers on their ongoing investment into high drug prices in order to increase future innovation. The implicit, critical and unrealistic assumption inherent in these studies is identified, namely that the health budget can be expanded to purchase drugs at higher prices without an opportunity cost, for example, the foregone benefits of alternative investments in health care infrastructure.

Price effectiveness analysis (PEA), is introduced. PEA informs the question of how the innovative surplus from the new drug should be allocated between the manufacturer and the consumer so as to optimise society’s welfare. The method allows the decisions by the regulator and the firm to be analysed jointly by specifying the firm’s production and revenue functions in terms of the clinical innovation of a new drug; the incremental effect used in the summary metric of cost effectiveness analysis. An economic value of innovation that takes into account opportunity cost under conditions of economic efficiency in the health system is proposed: the health shadow price.

The limitations of the non-strategic methods that currently inform the highly contested new drug subsidy game are presented and the relative strengths of PEA are demonstrated. Health technology assessment quantifies both the clinical innovation of a new drug and its financial impact on the health system. Cost effectiveness analysis tests the relationship between the incremental cost and incremental effect of a new drug for target patients, at a given price. PEA tests the relationship between the price of a new drug and the health of the whole population, now and into the future. It achieves this by taking into account current inefficiency in both resource allocation and the displacement process, and the relationship between price and future innovation.

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Opioid Dependence: A Clinical and Epidemiologic Approach 1st ed. 2018 Edition

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This unique and timely title offers a comprehensive assessment of the previously underappreciated risks and potentially overstated benefits of chronic opioid therapy.  It does so by approaching the rampant problem of opioid abuse and addiction – currently labeled an epidemic in the United States — from a public health/epidemiologic perspective.  That is, following a thorough overview in Part 1 that compares (and contrasts) classic infectious disease epidemiology concepts with the epidemic, the book categorizes our current understanding of basic science and best clinical practices in opioid therapy in terms of Agent (opioid), Vector (prescriber) and Host (patient) factors.  The majority of the book, which includes a plethora of instructional case studies, is organized according to these three arenas. Opioid Dependence: A Clinical and Epidemiologic Approach is designed to update all clinicians on opioid basic sciencecurrent areas of drug improvement research and development, alternatives to opioid therapy, evidence-based indications for opioid therapy, and clinical strategies for preventing and overcoming opioid dependence.  Importantly, an overview of clinical practice guidelines from the American Society of Addiction Medicine, with its biopsychosocial-spiritual “multidimensional assessment” focus is provided, along with a discussion of medication-assisted treatment, organized by the three currently FDA-approved pharmacotherapeutics (methadone, buprenorphine and naltrexone).  Developed for practitioners at every level, this ground-breaking title offers a fresh and novel approach to improving the care and outcomes of patients receiving opioid therapy.

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