Introduction to Biomolecular Structure and Biophysics: Basics of Biophysics 1st ed. 2017 Edition

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This comprehensive book presents a modern concept in biophysics  based on recently published research. It highlights various aspects of the biophysical fundamentals and techniques that are currently used to study different physical properties of biomolecules, and relates the biological phenomenon with the underlying physical concepts. The content is divided into nine chapters summarizing  the structural details of proteins, including recently discovered novel folds, higher order structures of nucleic acids, as well as lipids and the physical forces governing the macromolecular interactions which are essential for the various biological processes. It also provides insights into the  recent advances in biophysical techniques including Hydrogen Deuterium Exchange with Mass Spectrometry (HDX-MS), Small angle X-ray scattering (SAXS) and Cryo Electron Microscopy (cryo EM), supplemented with interesting experimental data.

It is a valuable reference resource for anyone with a desire to gain a better understanding of the fundamentals of biophysical concepts and techniques of important biomolecules.

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Fast Facts: Smoking Cessation 2nd Edition

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Cigarette smoking is the single largest preventable cause of death and illness in the industrial world, and accounts for 4.9 million deaths worldwide every year. “Fast Facts – Smoking Cessation” gives plenty of practical advice in a clear and eloquent style, along with current information about the effects of smoking on the body, of smoking cessation and the myths about smoking and quitting. The authors, both acknowledged experts in the field, have produced a concise and fascinating handbook that will prove invaluable to anyone who ever records smoking as a vital sign.

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Morbid Obesity in Adolescents: Conservative Treatment and Surgical Approaches

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As the worldwide prevalence of morbid obesity among adolescents continues to rise, recent years have seen a large increase in the performance of adolescent bariatric surgery. While surgical intervention often becomes necessary when conservative weight-loss therapies have failed, no standards regarding the post-operative regimen and long-term management of adolescent patients have been established. Thus, the treatment of obesity and its co-morbidities requires a multidisciplinary approach, taking into account epidemiological, clinical, nutritional and genetic aspects of morbid obesity in the pediatric age group.

This volume discusses both conventional therapy and surgical options for morbid obesity in the pediatric age group. In the first part, obesity-related diseases, genetics and psychological factors are analyzed. The second part focuses on current bariatric surgery procedures, including dietary restrictions and guidelines to prevent nutritional deficiencies common after surgery. Therefore, the book will prove an invaluable resource for pediatricians, surgeons, nutritionists, dieticians and all other health professionals who treat adolescent obesity.

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A Practical Clinical Guide to Resin Cements

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About the Author

Raising of Microvascular Flaps: A Systematic Approach 2nd ed

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Raising of Microvascular Flaps provides all those who deal with microsurgical tissue transfer, i.e. plastic surgeons, ENT surgeons, trauma surgeons, and oral and maxillofacial surgeons, with all they need to know in their daily practice. In this second edition, the authors have followed the principle of systematic teaching based on photographs of cadaver preparations alongside explanatory color drawings to enhance understanding of the anatomy. Since microvascular tissue transfer is continuously developing, three flaps from the new generation have been added. These perforator flaps expand the spectrum of reconstructive possibilities and have specific indications if very low donor site morbidity is important to patients. A special strength of the book is its clear didactic structure. The highly instructive text is comprehensive and precise and also covers all representative literature on flap raising.

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Clinical Facial Analysis: Elements, Principles, and Techniques 2nd ed

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This richly illustrated book presents a straightforward non-instrumental method of clinical facial analysis in preparation for aesthetic surgery, orthognathic surgery, and orthodontic treatments. After discussion of various practical aspects of facial examination and photography, analysis of different regions of the face and dentofacial deformities is discussed in a series of detailed chapters. At the end of each of these chapters, multiple-choice checklists are included that will help the reader to perform step-by-step regional analysis. Important features of the book are its multidisciplinary approach and the emphasis placed on the relationship between different parts of the face. This second edition has been thoroughly updated and includes a new chapter on recording and documentation relating specifically to aesthetic facial surgery.

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Sigma Receptors: Their Role in Disease and as Therapeutic Targets (Advances in Experimental Medicine and Biology) 1st ed. 2017 Edition

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Originally confused with opioid receptors and then orphan receptors with no biological function, Sigma Receptors are now recognized as relevant to many degenerative diseases with remarkable potential as therapeutic targets. In this text, new information about the structure of sigma 1 receptor, its binding sites are provided as well as its expression in many cell types.  It’s putative role in degenerative neuronal diseases including amyotrophic lateral sclerosis, Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, pain, drug addiction and locomotor activity. Their roles in possible treatments for blinding retinal diseases emphasize the tremendous far-reaching potential for ligands for these receptors.  Exciting breakthroughs in this dynamic field in the last decade are reported herein, which will guide future investigators in determining the full potential of this unique, yet abundantly expressed protein.

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Cell Therapy: Current Status and Future Directions (Molecular and Translational Medicine) 1st ed. 2017 Edition

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This volume provides a comprehensive, state-of-the art review of the field of cell therapy.  The volume begins with an overview of the breadth of the field and then turns to overviews of imaging technologies that can aid in both safety and efficacy evaluations. The book then turns to numerous contributions detailing the rapidly growing field of stem cell therapies. These sections cover our understanding of the natural roles of stem cells in biology and human disease and then touches on several of the more prominent areas where stem cells are moving rapidly into clinical evaluation including neurodegenerative diseases, muscular dystrophy, cardiac repair, and diabetes. The volume concludes with contributions from experts in oncology, ophthalmiology, stem cells, 3-D printing, and biomaterials where the convergence of expertise is leading to unprecedented insights into how to minutely control the in vivo fate and function of transplanted and/or endogeneously mobilized cells.  Finally, the book provides insights into the pivotal relationship between academic and industrial partnerships.
This volume is designed to touch on the major areas where the field will make its greatest and most immediate clinical impacts.  This text will provide a useful resource for physicians and researchers interested in the rapidly changing filed of cell therapy.

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Prime Mover: A Natural History of Muscle

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The story―and the science―of nature’s greatest engine.

Whether we blink an eye, lift a finger, throw a spear or a ball, walk, run, or merely breathe, we are using muscle. Although muscles differ little in appearance and performance across the animal kingdom, they accomplish tasks as diverse as making flies fly, rattlesnakes rattle, and squid shoot their tentacles.

Our everyday activities turn on the performance of nature’s main engine: we may breathe harder going uphill, but we put more strain on our muscles walking downhill. Those of us who are right-handed can tighten screws and jar lids more forcibly than we can loosen them. Here we’re treated to the story of how form and performance make these things happen―how nature does her work.

Steven Vogel is a leader in the great new field of bioengineering, which is rapidly explaining the beauty and efficiency of nature. His talents as both scientist and writer shine in this masterful narrative of biological ingenuity, as he relates the story―and science―of nature’s greatest engine.

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