Drug Interactions in Infectious Diseases: Antimicrobial Drug Interactions 4th ed. 2018 Edition

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The 4th edition of Drug Interactions in Infectious Diseases is being split into two separate volumes – “Mechanisms and Models of Drug Interactions” and “Antimicrobial Drug Interactions”.

This volume, “Antimicrobial Drug Interactions,” delivers a quick clinical resource that distills relevant drug interactions by antimicrobial drug class. The book provides informative tables on specific drug-drug interactions that include the degree and severity of the expected interaction. A mechanistic basis for drug-drug interactions is also provided to link observed interactions to pharmacologic characteristics of key drug classes. This complete resource is organized by major antibacterial, antimycobacterial, antiviral, antifungal, antimalarial, and antiprotozoal class. In line with current innovations in antimicrobial drug development, a distinct chapter on the pharmacologic management of drug interactions in hepatitis B virus (HBV) and hepatitis C virus (HCV)-related infections is included.  Two new chapters are dedicated to the management of human immunodeficiency virus (HIV) drug-drug interactions given the breadth of antiretroviral class-specific effects. This comprehensive review of known drug interactions and strategies to manage them is an invaluable resource to all health care practitioners.

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Influenza: Current Research Reprint Edition

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Influenza viruses are important pathogens responsible for flu epidemics and pandemics. The socio-economic impact of seasonal flu is very significant and the rapid rate of virus evolution necessitates the development of new vaccines every year. Another major challenge is the emergence of novel strains that are highly pathogenic for humans. Examples include H7N9 and H5N1 (emerged from birds) which have mortality rates of up to 30% and 60%, respectively. Research is underway to develop of a universal flu vaccine that would provide long-lasting protection and be effective against emergent strains.

Following on from their highly-acclaimed 2010 book, Drs. Wang and Tao present a new, up-to-date and comprehensive review of current advancements in molecular influenza virology. Topics covered include: stem-specific broadly neutralizing antibodies to the virus hemagglutinin; virus replication and transcription; influenza B virus hemagglutinin; influenza A virus ribonucleoprotein complex; regulation of the virus replication machinery by host factors; evolution of receptor specificity of influenza A virus hemagglutinin: PB1-F2, a multi-functional non-structural influenza A virus protein; and avian influenza H7N9 virus.

Highly informative and well referenced, this book is essential reading for all influenza specialists and is recommended reading for all virologists, immunologists, molecular biologists, public health scientists and research scientists in pharmaceutical companies.

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Fighting Infectious Diseases

Infectious, or communicable, diseases are a major global health concern. Managing and preventing the spread of diseases takes a concerted public health effort to deal with deadly outbreaks, epidemics and pandemics. This book reveals the global trends and challenges in the fight against the major types of infectious disease, and looks at vaccine-preventable diseases and immunisation in Australia. Are we doing enough to win the ongoing fight against infectious diseases? Also includes: worksheets and activities, fast facts, glossary, web links, index

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Bacterial Infections and the Kidney 1st ed

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This text is designed to present a comprehensive and state-of the-art but practical approach to the diagnosis and management of bacterial infection associated renal disease.  The chapters address the different types of glomerular, tubulointerstitial and vascular diseases, associated with bacterial infections, describe diagnostic pitfalls, provide differential diagnosis and discuss treatment and management. Easy to follow diagnostic algorithms and tables are included for practical usefulness. The text provides a large number of color microphotographs, illustrations and each chapter refers to the most important up to date literature in the area. All chapters are written by experts in the field and will include the most up-to-date clinical information. A comprehensive but user friendly resource on renal complications of bacterial infection, such as this book, is overdue, particularly now in the era of staphylococcus epidemic and emerging new resistant bacterial strains. Bacterial Infections and the Kidney will be an important resource for pathologists, nephrologists, general internists, infectious disease specialists, and urologists. Transplant surgeons may find the chapter on transplant pyelonephritis very useful.

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Lesser Known Large dsDNA Viruses (Current Topics in Microbiology and Immunology)

Several large dsDNA-containing viruses such as poxviruses (smallpox) and herpes viruses are well known among the scientific community, as well as the general populace, because they cause human diseases. The large dsDNA insect-infecting baculoviruses are also well known in the scientific community because they are used both as biological control agents and as protein expression systems. However, there are other large dsDNA-containing viruses, including the giant 1.2 Mb mimivirus, which are less well known despite the fact that all of them play important roles in every day life. Seven of these virus families are reviewed in this book.

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Disease Control Priorities, Third Edition (Volume 6): Major Infectious Diseases 3rd Edition

Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases.

The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.

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Fungal Allergy and Pathogenicity (Chemical Immunology and Allergy, Vol. 81)

The importance of fungal organisms as allergens and pathogens has been increasing considerably over the last decade. This is due, on the one hand, to a general increase in the incidence of allergies, but also to the growing number of immunocompromized individuals such as AIDS patients or transplant recipients. This book summarizes what is currently known about the allergens of Candida, Aspergillus, Cladosporium, Alternaria, Coprinus, and Psilocybe, among others, and describes the application of recombinant allergens for diagnosis and new forms of therapy. The virulence factors and defense mechanisms against Aspergillus and Candida infections are discussed as are the various causes of superficial skin infections with fungi and the aerobiology of fungal spores and mycelia. A comprehensive chapter on fungal toxins and their importance for human and animal health is included, followed by a summary of the present state of fungal genome sequencing. Finally, the now generally accepted new sequence-based systematics and phylogeny of allergenic and pathogenic fungi is presented. A glossary explains the highly specialized terminology of clinical and systematic mycology for the nonspecialist. Summarizing the most up-to-date molecular and clinical findings, this publication will be of interest not only to allergologists, mycologists and biologists, but to all clinicians who want to learn more about clinically important fungi as well as to lawyers concerned with lawsuits on ‘sick building syndrome’.

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A Practical Guide to Clinical Virology 2nd Edition

This Second Edition of A Practical Guide to Clinical Virology is a practical, highly illustrated, quick reference guide to clinical virology. It brings together the essentials of the subject in a entertaining and informative style, describing in turn the clinical features, the symptoms and signs of each of the viral diseases, as well as summarising the epidemiology, laboratory diagnosis and therapy in each case. This book also includes general chapters on classification, diagnosis of infection, antiviral drugs, vaccines and different clinical syndromes.

Key Features:

  • Chapter summaries for quick reference
  • Cartoon illustrations
  • Comprehensive coverage
  • Clear and concise format

Each chapter is easy to read and well organised, ensuring that this is an invaluable textbook for all medical, biomedical, microbiology and applied biology students. In addition, it provides an excellent reference for nurses, occupational health and infection control departments, public health and diagnostic laboratories.

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Opportunistic Infections: Toxoplasma, Sarcocystis, and Microsporidia (World Class Parasites)

Opportunistic Infections: Toxoplasma, Sarcocystis, and Microsporidiawill focus on two important Genera of Apicomplexan parasites, Toxoplasma gondii and Sarcocystis species, and the medically important members of the Phylum Microsporida. We have been fortunate in obtaining excellent contributions from many experts in the field.
Volumes in the “World Class Parasites” book series are written for researchers, students and scholars who enjoy reading about excellent research on problems of global significance. Each volume focuses on a parasite, or group of parasites, that has a major impact on human health, or agricultural productivity, and against which we have no satisfactory defense. The volumes are intended to supplement more formal texts that cover taxonomy, life cycles, morphology, vector distribution, symptoms and treatment. They integrate vector, pathogen and host biology and celebrate the diversity of approach that comprises modern parasitological research.

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CNS Infections: A Clinical Approach 2nd ed. 2018 Edition

This updated and expanded second edition covers selected infections of the central nervous system of considerable current interest. Aspects that are less well documented, such as spinal cord infections, central nervous system infections in patients with cancer, tropical infections, healthcare-associated ventriculitis or meningitis, and immunological problems in the international traveler are also discussed, as these are all problems relevant to daily practice. It is a multi-authored book written by experts in the field of neurological infection. A new section on infectious neuropathies is included.

CNS Infections: A Clinical Approach is of value to the busy clinician; the neurological international community as well as all primary care doctors, internal medicine specialists and residents who take care of patients with suspected neurological infections.

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