Hematologic Malignancies: Acute Leukemias

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Better therapy of acute leukemias depends ultimately on better understanding of the distinction between leukemic and normal progenitor cells. This hugely important new book describes the current knowledge of acute leukemia biology and discusses new classification systems that have arisen as a result of emerging insights into pathogenesis. Estey, Faderl and Kantarjian, who all work at the respected Anderson Cancer Center in Houston, Texas, USA, examine in detail advances in the treatment of particular types of acute leukemia. Their book also covers the management of acute leukemia in general as well as the development of new therapies. This book will be extremely useful to clinicians.

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Flow Cytometry in Neoplastic Hematology: Morphologic-Immunophenotypic Correlation, Third Edition 3rd Edition

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This third edition is the product of the author’s 25 years of experience with flow cytometry; although it covers the wide spectrum of hematopoietic tumors, the focus remains on most important clinical diagnoses, such as acute promyelocytic leukemia, identification of blasts, identification of clonal B-cell population, differentiating mature versus immature T-cell proliferations, deferential diagnosis between hematogones and B-ALL or distinction between chronic and acute monocytic proliferations. All hematopathologists and neoplastic hematologists will find this an important resource for keeping up to date with developments in clinical practice.

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Patient-specific Hemodynamic Computations: Application to Personalized Diagnosis of Cardiovascular Pathologies 1st ed. 2017 Edition

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Hemodynamic computations represent a state-of-the-art approach for patient-specific assessment of cardiovascular pathologies. The book presents the development of reduced-order multiscale hemodynamic models for coronary artery disease, aortic coarctation and whole body circulation, which can be applied in routine clinical settings for personalized diagnosis. Specific parameter estimation frameworks are introduced for calibrating the parameters of the models and high performance computing solutions are employed to reduce their execution time. The personalized computational models are validated against patient-specific measurements.

The book is written for scientists in the field of biomedical engineering focusing on the cardiovascular system, as well as for research-oriented physicians in cardiology and industrial players in the field of healthcare technologies.

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Blood Science: Principles and Pathology 1st Edition

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Blood Science is a relatively new discipline which merges biochemistry, haematology, immunology, transfusion science and genetics. This bringing together of traditional disciplines requires a corresponding change in education and training for healthcare scientists and Blood Science: Principles and Pathology is written in response to this emerging need.

An introduction to the subject and an overview of the techniques used in blood science are followed by a series of chapters based on groups of analytes investigated in blood – red blood cells, white blood cells and platelets, followed by the constituents of plasma, including waste products, electrolytes, glucose, lipids, enzymes, hormones, nutrients, drugs, poisons and others.

Each chapter is supported by learning objectives, summaries and further information, and a focus is given to chapter specific case studies with interpretation to demonstrate how laboratory data in conjunction with clinical details is utilised when investigating patients with actual or suspected disease. Finally, a separate chapter offers more detailed case reports that integrate the different aspects of blood science.

Undergraduate students taking blood science modules as part of their BSc programmes in Biomedical and Healthcare Sciences will appreciate the level of integration between clinical biochemistry and haematology. In addition, this book will provide suitable initial reading for those students embarking on blood science modules on MSc programmes and will be of value to new graduates entering the profession and starting their career in blood science departments by supplementing practice-based training with the required theoretical underpinning.

This book is approved by the Institute of Biomedical Science and written by its expert writers, many of whom work on the Institute’s advisory panels.

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Crash Course Haematology and Immunology, 4e 4th Edition

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The new series of Crash Course continues to provide readers with complete coverage of the MBBS curriculum in an easy-to-read, user-friendly manner. Building on the success of previous editions, the new Crash Courses retain the popular and unique features that so characterised the earlier volumes. All Crash Courses have been fully updated throughout.

  • More than 90 illustrations present clinical, diagnostic and practical information in an easy-to-follow manner
  • Friendly and accessible approach to the subject makes learning especially easy
  • Written by students for students – authors who understand exam pressures
  • Contains ‘Hints and Tips’ boxes, and other useful aide-mémoires
  • Succinct coverage of the subject enables ‘sharp focus’ and efficient use of time during exam preparation
  • Contains a fully updated self-assessment section – ideal for honing exam skills and self-testing
  • Self-assessment section fully updated to reflect current exam requirements
  • Contains ‘common exam pitfalls’ as advised by faculty
  • Crash Courses also available electronically!
  • Online self-assessment bank also available – content edited by Dan Horton-Szar!

Now celebrating over 10 years of success – Crash Course has been specially devised to help you get through your exams with ease.

Completely revised throughout, the new edition of Crash Course is perfectly tailored to meet your needs by providing everything you need to know in one place. Clearly presented in a tried and trusted, easy-to-use, format, each book in the series gives complete coverage of the subject in a no-nonsense, user-friendly fashion.

Commencing with ‘Learning Objectives’, each chapter guides you succinctly through the topic, giving full coverage of the curriculum whilst avoiding unnecessary and often confusing detail. Each chapter is also supported by a full artwork programme, and features the ever popular ‘Hints and Tips’ boxes as well as other useful aide-mémoires. All volumes contain an up-to-date self-assessment section which allows you to test your knowledge and hone your exam skills.

Authored by students or junior doctors – working under close faculty supervision – each volume has been prepared by someone who has recently been in the exam situation and so relates closely to your needs. So whether you need to get out of a fix or aim for distinction Crash Course is for you!!

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Hematologic Abnormalities and Acute Lung Syndromes (Respiratory Medicine) 1st ed. 2017 Edition

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This book provides a unique frame work for examining acute lung syndromes that arise from hematologic disorders or is defined by a hematologic abnormality as a key feature.  Acute lung processes arising from hematologic disorders can present as life-threatening conditions, and as such, the pulmonary physician or critical care physician are often directly involved in care or called upon to provide expertise. Chapters are organized into three sections, each with an emphasis on pathogenesis and current understanding of mechanisms. The text begins with the central theme of the lungs as the direct interface between the external environment and blood, description of individual components of the hematopoietic system, their function and relevance to the lungs. The second section outlines both benign and malignant primary hematologic disorders that can lead to acute pulmonary manifestations. The final section focuses on acute lung syndromes stemming from complications of transfusion and treatment. Chapters are presented in an easy-to-access format, providing information on diagnosis, management, and outcomes. This is a valuable resource for pulmonary fellows in training, pulmonologists, critical care physicians, and physicians involved in caring for patients in the ICU.

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Platelets in Thrombotic and Non-Thrombotic Disorders: Pathophysiology, Pharmacology and Therapeutics: an Update 1st ed. 2017 Edition

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This book reviews current science and applications in fields including thrombosis and hemostasis, signal transduction, and non-thrombotic conditions such as inflammation, allergy and tumor metastasis. It is a detailed, up-to-date, highly referenced text for clinical scientists and physicians, including recent developments in this rapidly expanding field. More than a scientific resource, this is also an authoritative reference and guide to the diagnosis.

Review

“The four editors have managed very well in having internationally renowned investigators reviewing their particular fields of interest related to platelet research and the result is a beautiful piece of work! I strongly recommend this book to those involved in medicine in general and vascular medicine and hemostasis and thrombosis research in particular!” H. ten Cate, Pathophysiology of Haemostasis and Thrombosis

“…provides a comprehensive, up-to-date and detailed insight into platelet biology…all the chapters are well written by leaders in their field…this book serves as an invaluable reference source and is a ‘must have’ for postgraduate students, clinicians and researchers, whether relative novices or experts in the field.” Transfusion Medicine

“[A] landmark in hematology…comprehensive coverage of platelet biology and pathology. The editors have assembled the best authors, and the authors have all provided thorough reviews with comprehensive, current citations.” The New England Journal of Medicine

“Such a comprehensive collection of platelet structure, function, and pathology has not been achieved before. This is the complete, comprehensive reference for platelets and it is invaluable to anyone who is involved in the treatment or the study of conditions related to platelets.” Doody’s Review Service

“There has been no comprehensive, timely, and authoritative reference book covering the subject in recent years. Platelets in Thrombotic and Non-thrombotic Disorders fills this gap by providing a book that is both detailed and exhaustive yet easily consulted for the latest developments.” Chest

“Obligatory reading for anyone who wishes to embark on platelet studies.” International Society on Thrombosis and Haemostasis

” Platelets in Thrombiotic and Non-thrombiotic Disorders is an highly informative and extensively referenced textbook that is highly recommended…” Immunohematology

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Leukaemia Diagnosis 5th Edition

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UP-TO-DATE PRACTICAL GUIDE TO LEUKAEMIA DIAGNOSIS

Written by a renowned expert this practical guide had been fully revised and updated. The book covers recent advances in the fields of immunophenotyping, cytogenetics and molecular genetics. It illustrates how laboratory techniques are used for the diagnosis and classification of leukaemia and includes images of abnormal cells to aid diagnosis.

This fifth edition:

  • Incorporates the recommendations of the 2015 WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues
  • Includes 300 high quality full colour digital images of abnormal cells in leukaemia and lymphoma
  • Full colour diagrams and helpful tables clarify and summarise key points throughout

Essential reading for every haematologist and haematopathologist.

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