General Practice ⋆ Page 19 of 35 ⋆ eMEDICAL BOOKS

Management of Anemia: A Comprehensive Guide for Clinicians

October 20, 2017

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This concise and practical resource brings together recent advances in identifying and managing anemia of chronic disease (inflammation), genetically related anemia and anemia related to chronic end organ damage. Chapters provide a detailed analysis of the current science of anemia, approaches to different patient populations, comorbid conditions and nutritional aspects of anemia. Novel therapies focused on physiological pathways are introduced and discussed. Controversies from the perspective of subspecialists focused in treating major causes of anemia within their specific disciplines are also presented. Easy-to-reference and authored by experts in each clinical scenario, Management of Anemiais the launching point for learning more about this challenging and common condition.

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The Parkinson’s Playbook: A Game Plan to Put Your Parkinson’s Disease On the Defense

October 20, 2017

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The Parkinson’s Playbook puts the power in your hands, giving you the knowledge you need to proactively defend yourself against the progression of Parkinson’s disease with energy, vitality, and confidence.

The diagnosis of Parkinson’s disease is not an easy one. In The Parkinson’s Playbook, author Robert Smith has prepared an enlightening and engaging “playbook” to help you tackle Parkinson’s head on, including a pro-active offense of lifestyle improvements and defensive measures including cutting-edge medications and natural healing techniques.

The Parkinson’s Playbook makes you the MVP of your life—so get out there and win!

Also featured in The Parkinson’s Playbook:
• How to assemble a line-up of medical and emotional support systems
• Learn the importance of exercise to boost strength and relieve stress
• Effective, easy-to-implement diet changes for well-being

…and so much more, all with the unique patient’s perspective of the author’s personal experiences fighting—and winning—against his disease.

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Opioid Dependence: A Clinical and Epidemiologic Approach 1st ed. 2018 Edition

October 20, 2017

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This unique and timely title offers a comprehensive assessment of the previously underappreciated risks and potentially overstated benefits of chronic opioid therapy. It does so by approaching the rampant problem of opioid abuse and addiction – currently labeled an epidemic in the United States — from a public health/epidemiologic perspective. That is, following a thorough overview in Part 1 that compares (and contrasts) classic infectious disease epidemiology concepts with the epidemic, the book categorizes our current understanding of basic science and best clinical practices in opioid therapy in terms of Agent (opioid), Vector (prescriber) and Host (patient) factors. The majority of the book, which includes a plethora of instructional case studies, is organized according to these three arenas. Opioid Dependence: A Clinical and Epidemiologic Approach is designed to update all clinicians on opioid basic science, current areas of drug improvement research and development, alternatives to opioid therapy, evidence-based indications for opioid therapy, and clinical strategies for preventing and overcoming opioid dependence. Importantly, an overview of clinical practice guidelines from the American Society of Addiction Medicine, with its biopsychosocial-spiritual “multidimensional assessment” focus is provided, along with a discussion of medication-assisted treatment, organized by the three currently FDA-approved pharmacotherapeutics (methadone, buprenorphine and naltrexone). Developed for practitioners at every level, this ground-breaking title offers a fresh and novel approach to improving the care and outcomes of patients receiving opioid therapy.

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Central Pain Syndrome: Pathophysiology, Diagnosis and Management (Cambridge Medicine (Hardcover)) 2nd Edition

October 19, 2017

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A fully updated new edition of this definitive, unrivalled, no-nonsense textbook, Central Pain Syndrome: Pathophysiology, Diagnosis and Management provides new treatment guidelines that aid the reader in effective management. • Encyclopedic coverage of all drug and surgical therapies, including the hot field of non-invasive and invasive cortical stimulation • 26 totally rewritten chapters include expanded sections on deep brain, spinal and other forms of stimulation, and a chapter on the efficacy of alternative and complementary medicine • Critical analysis of all current competing theories, including an expanded account of the leading dynamic reverberation theory which now incorporates a cortical attractor-based model • Clear-cut indications on drug usage, with black boxes for ineffective or dangerous drugs A classic textbook widely hailed on patients’ websites, this is key reading for medical specialists and trainees in pain management, neurology, neurosurgery and anesthesiology, as well as for patients

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Sepsis 1st Edition

October 15, 2017

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Sepsis or septic shock is a type of condition/infection which represents one of the leading post-surgical or post-traumatic complications. Sepsis is the major cause of morbidity and mortality in intensive care units worldwide. Also, sepsis is the leading cause of death in non-coronary patients, with pulmonary sepsis accounting for most cases as it relates to lung dysfunction. This is a concise, practical softcover volume devoted to covering only the most practical information for physicians. Charts, tables, and other figures are used to illustrate easy-to-follow treatment guidelines for those professionals who regularly treat patients in the ICU.

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Diagnostic Clusters in Shoulder Conditions 1st ed. 2017 Edition

October 10, 2017

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This book serves as a definitive guide to diagnosing shoulder conditions for trainees, general practitioners, physiotherapists, orthopaedic surgeons and radiologists with an interest in shoulder pathology. It comes at a time when the knowledge regarding shoulder conditions has vastly improved, with the shoulder sub-speciality growing at a rapid pace in terms of practitioner numbers, procedures and evidence base.

It is unclear, in most circumstances, which single clinical test or indeed radiological investigation is the best for diagnosing a particular condition. In fact, the diagnosis of a particular shoulder condition rests on the four sub-components of clinical history, conventional examination, special tests and radiological investigations. It is often the case that all these sub-components are to be used in conjunction with each other as “clusters” rather than in isolation. This forms the basis of the cluster approach, which is the key concept for the title and content of this book. This book presents a practical guide for diagnosis, written by a select group of surgeons and physiotherapists with a special interest in shoulder pathologies, who have painstakingly extracted these relevant clusters for each shoulder conditions from clinical experience and published work.

About the Author

Puneet Monga is a UK-based Consultant Orthopaedic Shoulder Surgeon at the Wrightington Hospital, and a Honorary Senior Lecturer at the University of Salford and Edge Hill University.

Lennard Funk is a UK-based Consultant Orthopaedic Shoulder Surgeon at the Wrightington hospital, and a Honorary Professor at the University of Salford.

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CBT Made Simple: A Clinician’s Guide to Practicing Cognitive Behavioral Therapy (The New Harbinger Made Simple Series)

September 25, 2017

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In CBT Made Simple, two psychologists and experts in cognitive behavioral therapy (CBT) offer the ultimate “how-to” manual based on the principles of effective adult learning. Structured around these evidence-based principles, this user-friendly guide will help you learn CBT and deliver it to your clients in the most optimal way.

CBT is a popular and proven-effective treatment for several mental health disorders, including anxiety, depression, obsessive-compulsive disorder (OCD), post-traumatic stress disorder (PTSD) and anger problems. However, there are no evidence-based learning techniques to teach it—until now. This simple, pragmatic guide offers everything you need to know about CBT: what it is, how it works, and how to implement it in session.

CBT Made Simple provides a user-friendly, practical approach to learning CBT using up-to-the-minute teaching methods and learning tools—in particular, the “effective adult learning model,” which promotes interactive learning, experiential learning, and self-reflection. Each chapter presents key elements of CBT in clear, accessible language, and includes client dialogues—including explanations of the therapist’s thinking process in relation to various interventions—and clinical examples. Practical exercises are incorporated throughout, enabling you to practice and consolidate your learning. In addition, each chapter mimics the structure of an actual CBT session.

If you are a clinician or student interested in learning more about CBT, this book—a new addition to the New Harbinger Made Simple series that includes ACT Made Simple and DBT Made Simple—has everything you need to hit the ground running. Why not make it a part of your professional library?

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Protein Deimination in Human Health and Disease 2nd ed. 2017 Edition

September 25, 2017

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Published in 2014, Protein Deimination in Human Health and Disease was the first book on this novel post-translational modification, in which selected positively-charged arginine amino acids are converted to neutral citrulline amino acids by the peptidyl-arginine deiminase (PAD) family of enzymes. This area of research continues to expand rapidly, necessitating the need for this second edition. Chronicling the latest inflammatory, epigenetic, neurodegenerative, and carcinogenic processes, Protein Deimination in Human Health and Disease, Second Edition, updates the latest advances in deimination research, including new information on PAD enzyme structure and activity, and how PAD knock-out animals are being used to study known and newly-discovered links to various human diseases.

The first edition outlined what was known about citrullinated proteins in normal tissues such as skin and hair, as well as in maladies such as rheumatoid arthritis (RA), multiple sclerosis (MS), Alzheimer’s disease (AD), glaucoma, peripheral nerve injury, neonatal hypoxic brain damage, and breast cancer. This second edition addresses numerous additional disorders such as diabetes, asthma, traumatic brain injury, inflammatory bowel disease, lupus, bone disease, heart failure, fronto-temporal dementia, and prostate and colon cancer. It also provides updates on the deimination research covering the three seminal diseases first linked to this process (RA, MS and AD), and details how auto-antibodies against citrullinated proteins contribute to disease. In addition, new hypotheses on the possible pathologic mechanisms of citrullinated myelin basic protein and glial fibrillary acidic protein are also proposed. This second edition also outlines the latest developments in therapeutic strategies, including the use of new PAD antagonists and innovative techniques such as micro-vescicles and stem cells as possible mechanisms to treat these conditions.

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Manual of Spine Surgery

September 22, 2017

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This manual of spine surgery has become necessary as a consequence of the rapid expansion of instrumented spine surgery using different minimally invasive and non-fusion techniques. To do justice to this development, the manual aims to present the different techniques to spinal surgeons (orthopaedic and neurosurgeons) in a clear and instructive way using detailed illustrations. The description of different open, less invasive or minimally invasive techniques will provide the spinal surgeon with useful guidelines for their use. The success of any spinal operation depends on good definition of the indications, consideration of the contraindications, technical and organisational factors, good operating technique and correct preoperative preparation and positioning of the patient. These points are presented in this book as clearly as possible and are illustrated with detailed high quality artwork.

About the Author

UWE VIEWEG is Head of the Department of Spine Surgery, Leopoldina Hospital, Schweinfurt, Germany. He is specialized in minimally invasive spine surgery, non-fusion technology, corrections of degenerative scoliosis and high-grade spondylolisthesis as well as quality control of different spine procedures. FRANK GROCHULLA is Head of the Department of Spine Surgery, EuromedClinic, Fürth, Germany.

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Regulation of Inflammatory Signaling in Health and Disease (Advances in Experimental Medicine and Biology) 1st ed

September 22, 2017

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This book discusses recent research in innate immunity, which has revealed a large number of receptors that sense the presence of microorganisms or cellular damage in tissues. In complex tissues, many of these sensing events occur simultaneously. Thus, the downstream signaling pathways need to be integrated so that an appropriate cellular inflammatory response can be initiated. In addition, the inflammasome defines the molecular and cellular processes of inflammation in response to microbial infection. Previous data suggested that regulation of inflammasomes is mediated by microbes, but inflammasomes also have antimicrobial functions. Increasing evidence in mouse models, together with human data, strongly implicates an involvement of the inflammasome and uncontrolled inflammation in the initiation and progression of diseases with a high impact on public health.

The book reviews novel aspects of functional genomics, epigenomics, transcriptomics, post-translat

ional modifications, microbiome and immunometabolism in order to understand inflammatory signaling and responses, covering recent findings on the mechanisms underlying the regulation of inflammatory responses to pathogens, dysregulation of these responses in inflammatory disease, and the use of such mechanisms to boost or subdue the inflammatory response. Bridging the gaps in understanding between the fields of human and mouse immunology, it provides valuable insights into inflammatory-mediated disease and immune defense. Such innovative perspectives in both basic and clinical research promote the translation of knowledge to the clinic.

About the Author

Dr. Dakang Xu is Professor at Shanghai Jiao Tong University and Institute of Ageing Research, Hangzhou Normal University, China. The main focus of his research team is to used a combination of genetically modified mouse models of disease, cell signalling, bioinformatics

analyses and clinical applications, to understand the mechanisms of regulation of epigenetic factors in inflammatory signalling. He has also studied how modulation of the activity of those key factors affects the inflammatory response and tumour progression, through the function of immune cell subsets and cytokines in cancer and inflammatory diseases. This work has led to 50 peer-reviewed publications in high impact journals, including Nature Immunology, Immunity, Nature Communications, PNAS and Cancer Research.

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