Advances in Artificial Pancreas Systems: Adaptive and Multivariable Predictive Control 1st ed. 2018 Edition

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This brief introduces recursive modeling techniques that take account of variations in blood glucose concentration within and between individuals. It describes their use in developing multivariable models in early-warning systems for hypo- and hyperglycemia; these models are more accurate than those solely reliant on glucose and insulin concentrations because they can accommodate other relevant influences like physical activity, stress and sleep.

Such factors also contribute to the accuracy of the adaptive control systems present in the artificial pancreas which is the focus of the brief, as their presence is indicated before they have an apparent effect on the glucose concentration and so can be more easily compensated. The adaptive controller is based on generalized predictive control techniques and also includes rules for changing controller parameters or structure based on the values of physiological variables. Simulation studies and clinical studies are reported to illustrate the performance of the techniques presented.

Clinical Psychopharmacology for Neurologists: A Practical Guide 1st ed. 2018 Edition

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This book provides neurologists with a basic knowledge of psychiatric medications.  It begins with general principles of psychopharmacology and the frequency of psychiatric illness in neurology patients. It goes on to cover psychoactive drugs in the elderly and treating behavioral symptoms of dementia.  There is a special emphasis on drug-drug and drug-diet interactions that may be seen in clinical practice.  Neurologists, residents, neuropsychiatrists, neuropsychologists and psychiatrists in training will find this practical guide invaluable in numerous clinical settings.

The Puzzle of Orofacial Pain: Integrating Research into Clinical Management VOL 15

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In recent years, progress in pain research has yielded substantial new insights, and this has profoundly altered our understanding of various orofacial pain conditions. Written by renowned international researchers and clinicians, this state-of-the-art textbook presents recent advances in the understanding of orofacial pain and offers evidence-based management approaches, thus bridging the gap between timely research findings and daily clinical practice. The reader is provided with helpful in-depth information of up-to-date advances in basic research as well as with the present knowledge of the pathophysiology, diagnosis and management of the five most common orofacial pain conditions. In addition, the psychosocial impact of orofacial pain in daily life and future developments are presented. Health care professionals, such as dentists, neurologists, physicians as well as students will find this volume helpful and valuable for an advanced understanding of the diverse orofacial pain conditions and for the improvement of patient care.

Clinical Pearls in Pulmonology 1st Edition

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Clinical Pearls in Pulmonology is a concise collection of pearls across ten pulmonology topics. Divided into ten chapters, the book covers topics such as chest percussion, tuberculosis, pneumonia, and radiology, presenting each in a question and answer format. Many procedures, therapies and clinical descriptions are accompanied by illustrations and tables to ensure clear understanding. Clinical Pearls in Pulmonology is a pocket-sized guide for undergraduates and junior residents, ideal for use on the go. Key Points Concise, illustrated collection of pulmonology pearls Topics include chest percussion, TB and radiology 82 images and illustrations

Botulinum Toxin Treatment in Clinical Medicine: A Disease-Oriented Approach 1st ed. 2018 Edition

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This book provides BoNT treatment menus for symptom-oriented therapy in 14 different disease categories.Each chapter starts with a brief description of the disease and its current treatment followed by an evidenced-based upon the published assertions of the Therapeutic Subcommittee of the American Academy of Neurology.  Each chapter includes case histories from editor’s vast experience of over 25 years with BoNT therapy and description of injection techniques enhanced by illustrative figures. Botulinum Toxin Treatment in Clinical Medicine includes an additional introductory chapter that discusses molecular structure, mechanism of action, toxin serotypes, immunogenicity and safety issues. Meanwhile, a concluding chapter provides information on potential future application of these toxins’ for treating symptoms of other specific diseases.

 

Metal Allergy: From Dermatitis to Implant and Device Failure 1st ed. 2018 Edition

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This volume has been compiled in response to the ongoing revolution in our understanding of metal contact allergy, and the ensuing challenge this has created for clinicians and others to synthesize large amounts of sometimes contradictory data. It opens by providing a comprehensive overview of the use and regulation of metals in our society, metal properties, and available testing methodologies. Common and uncommon metal allergens and sources of exposure are then reviewed in depth, and detailed sections are devoted to hypersensitivity to metal implants (which may be associated with device failure and/or dermatitis), metal allergy in select patient populations, and less frequently encountered manifestations of metal allergy.

The prevalence of metal allergy in the general population is high: up to 17% of people are allergic to nickel, and 1–3% to cobalt and chromium. Environmental sources of metal exposure include jewelry, clothing, electronic devices, coins, leather, diet, and occupational exposure. As metals are ubiquitous, this book will be an indispensable reference text for a wide range of clinicians and investigators, meeting the needs of all who are interested in metal allergy and its diagnosis and management.

Introduction to Molecular Vaccinology 1st ed

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This textbook provides an easy-to-understand introduction to the complex topic of vaccine research and development. It gives a comprehensive though clearly arranged insight to the most important aspects of molecular vaccinology, leading from the basics in immunology, to design of vaccines and mode of action of vaccines to the actual formulation, manufacturing and registration of vaccines. The volume is therefore a valuable text about modern vaccinology for graduate students and a basic introduction for newcomers in vaccine design and development.

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Joint Care of Parents and Infants in Perinatal Psychiatry

This book addresses key issues in perinatal mental health and discusses the different types of psychiatric care that may be appropriate for pregnant women, parents and infants, with emphasis on the need for joint care. The wide range of preventive measures, mainly applicable in primary care and the various potential curative interventions are examined in detail, with coverage of ambulatory care, day care and the role of mother and baby units. The importance of working in networks and joint decision-making strategies is explained. In addition, an overview of maternal perinatal psychopathology is provided and other relevant aspects are fully discussed, including the establishment of parent–infant interactions and the impacts of parental psychiatric illness on parenting skills and infant development. The book will be invaluable for adult and child psychiatrists, psychologists, psychotherapists, midwives, nurses and all others involved in the provision of perinatal psychiatric care.

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Tunnel Syndromes 3rd Edition

 

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The need for a comprehensive resource with easy-to-find information has increased with the addition of nine new syndromes. Tunnel Syndromes: Peripheral Nerve Compression Syndromes provides a quick overview of tunnel syndromes including the definition, anatomy, etiology, clinical signs and symptoms, and treatment. It presents a total of 50 tunnel syndromes. Following the tradition of the first two editions, this resource continues to probe the origins of tunnel syndromes and to propose probable causes that lead to them.

All existing chapters have been updated and new chapters have been added including:

  • Spinal accessory nerve syndrome
  • Intercostobrachial nerve syndrome
  • Notalgia paresthetica
  • Medial antebrachial cutaneous nerve syndrome
  • Distal posterior interosseous nerve syndrome
  • Medial superior cluneal nerve syndrome
  • Pudendus nerve syndrome
  • Lateral plantar nerve syndrome
  • Medial plantar nerve syndromeNew in this Edition:
  • New syndromes of clinical importance
  • Improved illustrations, including new magnetic resonance images
  • Twenty-seven new drawings (graphic designs) and twenty new photos
  • Updated references with a total of more than 1,650 citations

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Antisense Therapeutics (Methods in Molecular Medicine) 1st Edition

Leading researchers offer an authoritative survey and analysis of the latest findings on the rapid development of antisense oligonucleotides therapeutic and their application in various in vivo model systems. The book’s high-profile contributors provide timely accounts of their state-of-the-art strategies, discussing such topics as the synthesis and purification of oligonucleotides, their selection for a particular gene target, different methods of administration, and the use of various cell lines and cell culture systems. They also examine questions of cellular uptake, in vitro biological activity, in vivo biological activity, the pharmacology and pharmacokinetics of oligonucleotides, and the application of oligonucleotides to the central nervous system.

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