Epidemiology and Biostatistics: Practice Problem Workbook

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Epidemiology and Biostatistics: Practice Problem Workbook

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This workbook is designed to teach the major fundamental concepts in Epidemiology, Biostatistics, and clinical research design alongside the textbook “Epidemiology and Biostatistics, 2nd Edition”. It is written in concise and organized fashion with many examples to illustrate the concepts deriving from a collection of written materials created to teach Epidemiology and Biostatistics to medical students. The major differences from related titles include a “story” based approach toward teaching the material, relative brevity while maintaining focus on key concepts, and taking the perspective of first-time learners (avoiding and/or clearly defining jargon, using clear common-sense language). It features a variety of questions: long, short, and multiple choice questions. The workbook is made to provide students with the tools necessary to form their own informed conclusions from the clinical research literature.

Advances in Exercise and Health for People With Mobility Limitations 1st ed

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Advances in Exercise and Health for People With Mobility Limitations 1st ed

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The purpose of this book is to provide public health, disability, and rehabilitation professionals and practitioners evidence-based science with respect to health disparities faced by people with disabilities, especially people with mobility limitations; alternative methods of rehabilitation and exercise science for this population; assistive device technology; and, improved access to health care, employment, and social participation.

According to the National Institute on Disability, Independent Living, and Rehabilitation Research (NIDILRR), approximately 57 million Americans live with a disability. Disability severity and types vary considerably, such that each individual with a disability faces unique physical, social, and environmental barriers in order to enjoy quality of life and full participation in society. A large research literature shows that people with disabilities face substantial employment and health disparities compared to people without disabilities. People with mobility limitations often experience secondary conditions to compound their primary disability. Hollar (2013) and Hollar and Lewis (2015) showed that people with mobility limitations were significantly more likely to experience obesity and lack of access to physical exercise. Other studies have shown that access to proper physical examination facilities and equipment remain a substantial barrier in many clinics and hospitals despite the enactment of the Americans with Disabilities Act 25 years ago. Research on alternative exercise programs and new assistive device technologies offers promise to improve physical functioning and exercise for people with mobility limitations. Furthermore, increased focus on biopsychosocial over traditional medical models for disability will help policymakers and the public to recognize the complex, contextual issues (e.g., personal, social, environmental) that affect the lives of people with disabilities.

Readership includes public health practitioners and educators, disability and rehabilitation researchers, clinicians and sports medicine practitioners, and disability advocates. There have been general handbooks on disability, but advances in technology and alternative exercise programs, as well as novel disability health programs, are dispersed in the research literature. This book will help to highlight these programs for health policy experts, especially given the high health and social disparities experienced by this population.

Rare Rheumatic Diseases of Immunologic Dysregulation

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Rare Rheumatic Diseases of Immunologic Dysregulation

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This book is a practical, user-friendly guide for diagnosing and treating patients with rare rheumatic diseases of immunologic dysregulation. Covering uncommon diseases such as IgG4-Related Disease, Castleman’s Disease, and Felty Syndrome, chapters aggregate information from case reports and anecdotal literature to create a single, comprehensive handbook for treating patients. Each chapter provides historical perspective and epidemiology; a literature review (including research trials, translational research, historical and current case reports, and case series); pathogenesis; clinical presentation; laboratory evaluation; imaging; histopathology; treatment; and outcomes. Rare Rheumatic Diseases of Immunologic Dysregulation is an invaluable resource for rheumatologists, rheumatology fellows, and clinical immunologists to better diagnose and treat patients with rare rheumatic diseases.

Estrogen Receptor and Breast Cancer: Celebrating the 60th Anniversary of the Discovery of ER

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Estrogen Receptor and Breast Cancer: Celebrating the 60th Anniversary of the Discovery of ER

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The discovery of ER by Dr. Elwood Jensen exactly 60 years ago has not only led to the birth of a whole new vital nuclear receptor research field but also made a rapid, direct and lasting impact on the treatment and prevention of breast cancer. Since that landmark discovery, tremendous progress has been made in our understanding of the molecular functions of ER and development of targeted therapies against ER pathways for breast cancer treatment. However, there is currently no book available addressing these discoveries and recent advancement in a historical and systematic fashion. This book is intended to provide comprehensive, most up-to-date information on the history and recent advancement of ER and breast cancer by world renowned leaders in the field. These chapters include the history of the discovery of ER; physiological and pathological roles of ER; recent discovery of ER cistrome, transcriptome and its regulation of noncoding RNAs such as microRNAs and enhancer RNAs in breast cancer; development and clinical practices of the first targeted therapy Tamoxifen and other antiestrogens for breast cancer treatment; structural basis of ER and antiestrogen actions; molecular insights into endocrine resistance; the role of ER mutants, ER-beta and environmental estrogens in breast cancer; and emerging state-of-the-art therapeutic approaches currently in development to overcome treatment resistance and future perspectives. The book will provide undergraduate and graduate students, basic scientists and clinical cancer researchers, residents, fellows, as well as clinicians, oncology educators and the general public a thorough and authoritative review of these exciting topics.

Co-existing Diseases and Neuroanesthesia 1st ed

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Co-existing Diseases and Neuroanesthesia 1st ed

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This book provides basic information on neuroanesthesia, comprehensively discussing the brain and spine anatomy, physiology and relevant pharmacology. It also explores various co-existing medical conditions in neurosurgical patients and their medical management relevant to anesthesia, with each problem presented in a standard format. Written by experts in the field and including illustrations, flowcharts and images, each chapter begins with a brief clinical scenario and include the latest evidence-based information. This book is a valuable guide for all anesthetists, not only dedicated neuroanesthetists.

Electron Spin Resonance Spectroscopy in Medicine 1st ed

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Electron Spin Resonance Spectroscopy in Medicine 1st ed

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This book examines various applications of electron spin resonance spectroscopy (ESR) in medicine, covering topics such as interactions between blood and nanoparticles, physical intricacy of HbNO complexes, parasitic diseases, oxidative stress measurement, polymerization of resinous materials used in dentistry, tooth dosimetry and dermatological applications.

Instead of providing mathematical details, it focuses on the applications and data interpretation of ESR as an emerging tool.

This book is intended for students and researchers interested in the field of ESR applications in translational research and medicine.

Advances in Understanding Aortic Diseases

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Advances in Understanding Aortic Diseases

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Following the first international symposium ever held in Asia on Advances in Understanding Aortic Diseases (AUAD), this volume of proceedings contains the papers presented in both the oral and poster sessions. The 8th AUAD symposium greatly contributed to the understanding of aortic diseases, especially in Asia. Aortic diseases, specifically thoracic aortic diseases, are more common in Japan than in Western countries, which adds further importance to this compilation that covers recent improvements and advances in thoracic aortic surgery and its outcomes. Divided into lectures, panel discussions, symposiums, and poster sessions, the book includes, among other topics, advances in imaging and diagnosis with 3D-CT, MRS, and US; state-of-the-art repair of the thoracic aorta; novel aspects of aortic root replacement; reconstruction; and prosthetic graft surgery. This valuable collection of work provides the reader with an increased knowledge and understanding of aortic diseases not only in Japan but worldwide.

Basic Surgical Skills and Techniques 1st Edition

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Basic Surgical Skills and Techniques 1st Edition

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Provides knowledge about the basic set of practical skills in patient care with latest advances made in surgical technology so as to master the techniques. Intended for learning by senior medical students, interns, house surgeons for postgraduation examinations. It will be of immense use to students studying the art and science of surgery as it briefly guides about the care in use of tools in operation theaters and emergency rooms. It is designed to enhance practical training in a clinical environment. This book contains simple diagrams with explanations to learn from scrubbing up to suturing up. 1. Srubbing, Gowning and Gloving Techniques, 2. Knot Tying Techniques, 3. Wound Closure Techniques, 4. Surgery of Common Skin Lesions under Local Anesthesia, 5. Sutures in Surgery, 6. Patient Positioning during Surgery, 7. Anastomosis in Surgery, 8. Instrument Handling, 9. Drains in Surgery, 10. Minimally Access Surgery, 11. Hemostasis, 12. Biopsy Techniques, 13. Dissection Techniques, 14. Surgical Diathermy: Principles and Precautions, 15. Dressings and Wound Care.

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