Immune Infertility: Impact of Immune Reactions on Human Fertility 2nd ed. 2017 Edition

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This book offers  comprehensive coverage of both basic and clinical aspects of immune reactions responsible for infertility. It has  four sections focusing on Sperm antigens, Antisperm antibodies (ASAs),  Clinical impact of ASAs, and Immune contraception,  and include contributions from leading experts in these fields. This new edition of the book offers a comprehensive update that reflects the very significant advances in reproductive immunology that have been achieved over the past five years, especially related  to the sperm proteome, sperm-egg binding/fusion proteins, gene knockout studies, and immunocontraception. Reproductive immunology continues to be a fast-growing discipline in which new knowledge is emerging almost every day. Immune Infertility is a model source of vital and reliable information on the latest scientific developments in the field. It will be of value for clinicians, scientists, students, residents, and fellows working in reproductive biology, obstetrics and gynecology, and urology.

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Primary Sclerosing Cholangitis: Current Understanding, Management, and Future Developments 1st ed. 2017 Edition

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This text provides a state-of-the art review of primary sclerosing cholangitis (PSC). The volume focuses on new data about risk factors for PSC, its natural history of the disease, and the epidemiology and genetics of PSC, while providing a comprehensive overview on current and future therapies for PSC, management of cholangiocarcinoma, and other hepatobiliary malignancies. It also touches upon up-to-date surgical and endoscopic management, including liver transplantation- both deceased donor and living related liver transplantation.
Written by experts in the field, Primary Sclerosing Cholangitis: Current Understanding, Management, and Future Developments is a valuable resource for clinicians, surgeons and researchers with an interest in biliary liver disease, inflammatory bowel disease, and liver transplantation.
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Respiratory Endoscopy 1st ed. 2017 Edition

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This book provides a detailed overview of the latest innovations in respiratory endoscopy, from both diagnostic and therapeutic perspectives; each chapter focuses on one disease and the techniques for early diagnosis as well as treatment. It comprehensively covers treatment and procedures, including simultaneous X-ray fluoroscopy and its use during bronchoscopic procedures. This fast-developing technology is essential for the medical management of non-malignant and malignant diseases of the chest, especially lung cancer. Respiratory Endoscopy describes the cooperation between all the members of the healthcare team, and as such is a valuable resource not only for medical staff, but also for radiological technicians and nursing staff who contribute significantly in the care of the patients undergoing these invasive procedures. By promoting teamwork and providing practical know-how, it will improve the success and safety of respiratory endoscopy procedures.

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Resistance to Targeted Therapies Against Adult Brain Cancers (Resistance to Targeted Anti-Cancer Therapeutics) 1st ed. 2016 Edition

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This volume will bring together a review of research being carried out by international experts in this field, detailing treatment and research approaches in several forms of malignant brain tumors. These include glioblastoma (GBM), a highly aggressive and fatal form of astrocytoma which accounts for 80% of newly diagnosed brain tumor patients per year, and meningioma, of which 10% are malignant and extremely resistant to targeted therapies. The volume will also include a discussion of methods to overcome blood-brain barrier exclusion for more efficient targeted drug delivery in all forms of brain cancer treatment. The volume will include information on the repurposing of drugs in an attempt to circumvent drug resistance, use of small molecule inhibitors in GBM treatment, mechanisms of secondary brain metastasis, drug resistance, and state-of-the-art imaging of targeted therapies.

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Cardiac Gene Therapy: Methods and Protocols (Methods in Molecular Biology) 1st ed. 2017 Edition

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This detailed book provides methodological information on cardiac gene delivery, from classic to state-of-the-art technologies and techniques. Efficient, cardiac-specific, and safe vectors, as well as refined vector delivery methods, are key for successful cardiac gene transfer and eventually for improving patients’ outcomes. Newer vectors and more efficient vector delivery methods have the potential to dramatically improve gene transduction efficacy, while novel gene manipulation techniques enforce the therapeutic power and broaden disease targets. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Authoritative and practical, Cardiac Gene Therapy: Methods and Protocols serves as a valuable tool for molecular biologists and physiologists in the cardiology field conducting cardiac gene transfer research, which will ultimately lead to further advancements in the vital field.
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Cancer Cytogenetics: Methods and Protocols (Methods in Molecular Biology) 1st ed. 2017 Edition

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This volume provides readers with detailed protocols covering the main cancer cytogenetics techniques needed for clinical utilization and research purposes. The chapters in this book cover topics such as chromosome preparation for myeloid malignancies; chromosome bandings; fluorescence in situ hybridization probe preparation; array-based comparative genomic hybridization; and cytogenetic nomenclature and reporting. The updated reviews on chromosomal abnormalities in hematological malignancies are excellent guides for cytogenetics data interpretations and specific malignant diseases correlation. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Cutting-edge and comprehensive, Cancer Cytogenetics: Methods and Protocols is a valuable resource for the novice in cytogenetics because it provides helpful guiding protocols, but it’s also great for those who are already engaged in the field and are looking for some technical hints.

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Metagenomics: Methods and Protocols (Methods in Molecular Biology) 2010th Edition

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Metagenomics has proven to be a powerful tool for exploring the ecology, metabolic profiling, and comparison of complex microbial communities as well as its important applications in the mining of metagenomes for genes encoding novel biocatalysts and drug molecules for bioindustries. In Metagenomics: Methods and Protocols, expert researches provide an overview and introduction to basic methods commonly used in laboratories that have a strong background in microbial metagenomics. The book attempts to address all of the working steps involved in this crucial field, beginning with DNA isolation from soils and marine samples and continuing with the construction and screening of libraries, along with key advise involving bioinformatic tools available to analyze large metagenomic sequence data sets. Written in the highly successful Methods in Molecular Biology™ series format, chapters include brief introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Metagenomics: Methods and Protocols serves as a very complete guide to available screening protocols for all major biocatalysts in order to allow for the easy setup of these screens in any microbiology lab.

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Absolute Dermatology Review: Mastering Clinical Conditions on the Dermatology Recertification Exam 2016th Edition

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Each dermatologist that was board certified after 1992 is required by the American Board of Dermatology to take a recertification exam every ten years. One of the major components of the exam is to be able to identify clinical photographs of approximately 200 skin diseases, and while there are other components to the test, they vary according to subspecialty. However, everyone is required to identify the images, so several months before the exam, the American Board of Dermatology releases a list of the skin diseases that will be tested, but does not provide the images or reveal which ones will appear.
Review of Clinical Conditions for the Dermatology Recertification Examination provides a thorough, concise review of clinical images of the specific conditions that the reader will be required to recognize during the American Board of Dermatology recertification test.  In addition, concise key clinical features for each image will be provided that will assist the reader in recognizing the clinical images on the examination, enabling them a more efficient way to study for the test without having to look up images online or in a large text book. Written by a board certified dermatologic surgeon who recently took the recertification exam, this book proves indispensable to dermatologists taking the exam or residents who want a quick reference of the clinical appearances of the main conditions generally encountered by a dermatologist.

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Primary Care for Emergency Physicians 1st ed. 2017 Edition

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This book is written for physicians who work within an emergency department or urgent care setting to provide them with a treatment plan for those patients who are deemed not to have an emergency medical situation and can be safely treated as an outpatient. Emergency physicians (EPs) see a wide variety of patients and ostensibly for emergency reasons. However, many patients present to the emergency department for primary care-related reasons due to multiple factors or are diagnosed with potentially chronic problems that require a primary care intervention. Examples include a new diagnosis of hypertension (without hypertensive emergency) or diabetes. Thus, it is prudent for the EP to learn about basic primary care management of these conditions. Unfortunately, the training of EPs does not include these conditions, and they are left to guess appropriate treatment or to start a new medication that may not be appropriate.  This book aims to fill this gap by educating the EP on basic primary care interventions for specific conditions.

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Processing of Hyperspectral Medical Images: Applications in Dermatology Using Matlab® (Studies in Computational Intelligence) 2017 ed. Edition

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This book presents new methods of analyzing and processing hyperspectral medical images, which can be used in diagnostics, for example for dermatological images. The algorithms proposed are fully automatic and the results obtained are fully reproducible. Their operation was tested on a set of several thousands of hyperspectral images and they were implemented in Matlab. The presented source code can be used without licensing restrictions. This is a valuable resource for computer scientists, bioengineers, doctoral students, and dermatologists interested in contemporary analysis methods.

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