Radiation Therapy for Extranodal Lymphomas 1st ed. 2017 Edition

This book is devoted to sharing the knowledge and experience of expert radiation therapy (RT) for extranodal lymphomas. For that purpose, the authors provide clinical-pathological information, precise RT techniques, and treatment results, i.e., disease control and survival, of all extranodal lymphomas.

Over the past 10 years, specific techniques have been updated, from 3-dimensional conformal RT to intensity modulated RT / volumetric-modulated arc therapy. Precise targeting such as image-guided RT and active breathing control are now capable of treating lymphoma lesions that shift with respiration or peristalsis.

This book, serving as a guide, provides the necessary knowledge for radiation oncology, practice, and planning involving the RT techniques of treating extranodal lymphomas. In addition, it equips oncologists, hematologists, and medical oncologists to refer patients with extranodal lymphomas to radiation oncologists for appropriate treatment in a timely manner. Therefore this volume will greatly benefit all oncologists, including radiation and medical oncologists, as well as hematologists.

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Innovation of Diagnosis and Treatment for Pancreatic Cancer 1st ed. 2017 Edition

This collection of chapters describes in detail the latest insights into the evaluation of resectability and neoadjuvant therapy to pancreaticoduodenectomy and distal pancreatectomy for pancreatic cancer. Shedding light on immunotherapy and gene therapy, this volume comprehensively covers treatments and procedures for the disease, allowing surgeons and trainees to gain an overview and explore innovative treatments. It also provides information on various cases using tools such as endoscopic ultrasound, MDCT, PET for diagnosis and laparoscopy and robotic resection methods.
Edited and authored by pioneering professionals, Diagnosis and Treatment for Pancreatic Cancer is a valuable resource for gastroenterologists, medical oncologists, surgical oncologist and general surgeons interested in treatment of pancreatic cancer care.

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Cancer and Chemoprevention: An Overview 1st ed. 2017 Edition

This book focuses on the most recent, relevant, comprehensive and significant advances in cancer and chemo prevention. It broadly discusses cancer, its hallmarks and classification, molecular mechanisms of outbreak, contributing factors, role of oxidative stress, inflammatory mediators and evading apoptosis, which leads to the progression of disease.

Though modern medicine has left us with no option to treat this deadly disease due to drawbacks associated with conventional treatment – like its non-targeted nature, drug resistance, varied organ toxicities and unaffordability – chemoprevention offers a viable therapeutic window.

Given chemoprevention’s importance in the present scenario, the book highlights various chemo preventive strategies currently used in the management of cancer; a selection of novel chemo preventive agents used at clinics and in the pre-clinical stage; hurdles to effective chemoprevention; future prospects and the road ahead. It offers a valuable guide for all graduate students and researchers seeking information on cancer and chemoprevention in general, irrespective of the specific type/pathways involved in its onset.

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Dendritic Cells in Cancer 2009th Edition

It covers all aspects of DC generation, function, survival and antitumor activity in the tumor environment both in vivo and in experimental in vitro systems. The goal in focusing on a spectrum of issues related to DC in cancer is to provide an extensive and expansive review rather than a collection of independent analyses from different authors.

Specific topics to be covered include analysis of DC behavior in the tumor microenvironment, including endogenous and exogenous DC, multiple DC populations, molecular pathways responsible for DC dysfunction, tumor-derived factors altering DC polarization and activation, mechanisms of DC alterations, and the role of DC in tumor escape from immune recognition and elimination. Furthermore, additional chapters provide extensive analysis of the consequences of cancer therapy on the DC system and how aging impacts DC function in the tumor microenvironment. Finally, chapters are included examining strengths and pitfalls of current methodologies for generating DC from cancer patients for therapeutic purposes and on the role of tumor-mediated modulation of the DC system in cancer immunotherapy.

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Ovarian Cancer: Second Edition (Cancer Treatment and Research) 2nd ed. 2010 Edition

Ovarian carcinoma continues to be responsible for more deaths than all other gynecologic malignancies combined, due to a continued inability to achieve detection of early (rather than advanced) stage disease and the lack of effective tumor-specific therapeutics.

Ovarian carcinogenesis, invasion, and metastatic dissemination require a complex cascade of interrelated genetic, molecular, and biochemical events that regulate the neoplastic transition of normal ovarian surface epithelium.

This updated second edition includes exciting new advances in ovarian cancer detection and treatment and provides an analysis of current research into aspects of malignant transformation, growth control, and metastasis. A more detailed understanding of these processes may ultimately translate into the development of novel approaches for the detection and control of ovarian cancer.

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Cancer Cytogenetics: Chromosomal and Molecular Genetic Abberations of Tumor Cells 3rd Edition

The preeminent book on cancer cytogenetics—now in a valuable new edition

Like its successful predecessors, Cancer Cytogenetics, Third Edition continues to offer authoritative coverage of neoplastic processes at the chromosomal level of genomic organization. Now updated and expanded, this new edition includes detailed information on the most recent advances in the field, incorporating a vast amount of new cytogenetic as well as molecular genetic data from the latest basic and clinical investigations.

Edited by two leading authorities, who are now aided by a panel of internationalexperts, this new edition has been updated to include:

  • Greatly expanded coverage of solid tumors
  • Enhanced coverage of acute and chronic myeloproliferative disorders
  • The latest findings on acute and chronic lymphoproliferative disorders

Cancer Cytogenetics, Third Edition is a valuable resource for researchers in a wide range of fields, including cytogenetics, medical and molecular genetics, cellular and molecular biology, oncology, and hematology. With its complete coverage of thecytogenetic mechanisms underlying neoplasia, and always with a keen eye on the clinical consequences of the various acquired genetic aberrations, this text will alsobe an indispensable reference for all clinicians involved in the diagnosis and treatment of cancer patients.

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Cancer Biology and the Nuclear Envelope: Recent Advances May Elucidate Past Paradoxes (Advances in Experimental Medicine and Biology)

“Nuclear envelope (NE) defects have been linked to cancer biology since the mid-1800s, but it was not until the last few years that we have begun to understand these historical links and to realize that there are myriad ways that the NE impacts on tumorigenesis. The NE  is a complex double membrane system that encloses the genome while providing structural support through the intermediate filament lamin polymer and regulating protein/ mRNA trafficking and signaling between the nucleus and cytoplasm via the nuclear pore complexes (NPCs). These functions already provide some mechanisms for NE influences on cancer biology but work in the past few years has elucidated many others. Lamins and many recently identified NE transmembrane proteins (NETs) have been now shown to function in DNA repair, regulation of cell cycle and signaling, apoptosis, cell migration in metastasis and nuclear architecture and morphology. This volume presents a comprehensive overview of the wide range of functions recently identified for NE proteins and their relevance in cancer biology, providing molecular mechanisms and evidence of their value as prognostic and diagnostic markers and suggesting new avenues for the treatment of cancer. Indeed some of these recent links are already yielding promising therapies, such as the current clinical trial of selective inhibitors of the nuclear export factor exportin in certain types of leukemia, melanoma and kidney cancer.”

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Aggressive Breast Cancer (Cancer Etiology, Diagnosis and Treatments) 1st Edition

Breast cancer is the most common cause of cancer in women and the second most common cause of cancer death in women in the U.S. While the majority of new breast cancers are diagnosed as a result of an abnormality seen on a mammogram, a lump or change in consistency of the breast tissue can also be a warning sign of the disease. Heightened awareness of breast cancer risk in the past decades has led to an increase in the number of women undergoing mammography for screening, leading to detection of cancers in earlier stages and a resultant improvement in survival rates. Still, breast cancer is the most common cause of death in women between the ages of 45 and 55.This new book presents the latest research in the field.

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Liquid Biopsy in Cancer Patients: The Hand Lens for Tumor Evolution (Current Clinical Pathology) 1st ed. 2017 Edition

This text is designed to provide readers with a useful and comprehensive resource and state-of-the-art overview about the new, growing and fast-expanding field of “liquid biopsy” for the management of cancer patients. The liquid biopsy represents an important turning point in oncology since it provides a tool for a serial monitoring of disease. Liquid biopsy is our “hand lens” to follow molecular changes that characterize tumor development and progression. The book provide a unique and valuable resource on the clinical relevance of liquid biopsy as well as on the technical aspects of liquid biopsy analysis. All invited authors are recognized experts in their field.

 
Liquid Biopsy in Cancer Patients: The Hand Lens for Tumor Evolution is targeted to resident and fellows physicians, medical oncologists, molecular biologists and biotechnologists.

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Dynamic Contrast-Enhanced Magnetic Resonance Imaging in Oncology (Medical Radiology)

Dynamic contrast-enhanced MRI is now established as the methodology of choice for the assessment of tumor microcirculation in vivo. The method assists clinical practitioners in the management of patients with solid tumors and is finding prominence in the assessment of tumor treatments, including anti-angiogenics, chemotherapy, and radiotherapy. Here, leading authorities discuss the principles of the methods, their practical implementation, and their application to specific tumor types. The text is an invaluable single-volume reference that covers all the latest developments in contrast-enhanced oncological MRI.

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