An Introduction to Clinical Research (Success in Medicine) 1st Edition

This practical book is written specifically for junior doctors by a team of highly experienced authors, as an introductory guide to clinical research. It covers all areas that a junior doctor needs to consider, including funding, study design, ethics, data analysis, disseminating findings, and furthering one’s research career. It presents a balance view of clinical research and is written by authors actively involved in clinical research both at the ‘coal-face’ and at a more supervisory level.

Research can be a difficult process and it is essential to make sure that the project is set up in the correct way in order to get verifiable results. This easy-to-read guide is available to help junior doctors develop a good study design and present evidence of a sound academic practice, which will make obtaining funding more likely and be time-efficient. Getting started early in research and developing a solid, gradual understanding of clinical research through using this approachable book will be of huge benefit to junior doctors and their discipline.

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Principles and Practice of Clinical Electrophysiology of Vision (MIT Press) second edition Edition

This authoritative text is the only comprehensive reference available on electrophysiologic vision testing, offering both practical information on techniques and problems as well as basic physiology and anatomy, theoretical concepts, and clinical correlations. The second edition, of the widely used text, offers extensive new material and updated information: 65 of the 84 chapters are completely new, with the changes reflecting recent advances in the field. The book will continue to be an essential resource for practitioners and scholars from a range of disciplines within vision science.

The contributions not only cover new information — important material that is likely to become more important in the next decade — but also offer a long-range perspective on the field and its remarkable development in the last century. After discussing the history and background of clinical electrophysiology, the book introduces the anatomy of the retina and principles of cell biology in the visual pathways at the molecular, physiological, and biochemical levels. It relates these new findings to the techniques and interpretations of clinical tests, including the electro-oculogram (EOG), electroretinogram (ERG), and visual evoked potentials (VEP), which are discussed in detail, as are equipment, data acquisition and analysis, principles and protocols for clinical testing, diseases and dysfunction, and animal testing. Notable additions for this edition include chapters on the origin of electroretinogram waveforms, multifocal techniques, testing in standard laboratory animals, recent advances in analysis of abnormalities in disease, and the applications of these techniques to the study of genetic abnormalities.

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Clinical Physiology and Pharmacology: The Essentials 1st Edition

This book is an accessible collection of case study scenarios ideal for physiology and pharmacology revision for pharmacy, medical, biomedical science, clinical science and healthcare students.

Clearly structured and organized by major organ system, the book emphasises ways in which key signs and symptoms of disease inform diagnosis and the choice of treatment, together with the relevant pharmacological mechanisms. Each chapter has a clinical focus and includes clear learning outcomes, key points and model answers with detailed explanations designed to enhance students’ understanding of the physiology and pharmacology underpinning each case study scenario.

50 topics are covered and the cases presented include an extensive range of psychological, neurological, endocrine, cardiovascular, respiratory, renal, gastrointestinal and reproductive disorders, their symptoms, complications and usual treatment along with the actions and uses of some widely- used drugs.

  • An essential revision text designed to help students apply their theoretical knowledge to real-life cases
  • Realistic case studies focusing on commonly occurring conditions and diseases
  • Model answers throughout
  • Learning outcomes provided at the beginning of each chapter
  • Key learning points presented in the cases follow each model answer
  • Helps students to understand the relevance and clinical implications of the topics studied in physiology and pharmacology courses
  • Reinforces  major concepts and definitions
  • Includes a glossary with a full list of drugs and disorders to support the text
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Heart Rate Training

If you’re serious about your sport, you’re serious about conditioning. Now, with one small device, you can apply the latest technology, science, and research to take the guesswork out of training, monitor progress, and see results. Heart Rate Training will show you how!

From functions, features, and operational advice for your device to interpreting and applying the results, Heart Rate Training is a step-by-step guide to optimizing performance. You’ll learn how, when, and why monitors can, and should, be incorporated into your workouts, training, and conditioning program to produce maximum results.

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Clinical Medicine 4th Edition

This new edition is a comprehensive guide to clinical medicine correlating clinical findings with pathological processes. Divided into two parts, the first section examines internal medicine and each of the systems in the human body. The second section discusses functions and processes of these systems. Each chapter describes the investigation and examination of common disorders in each of the body systems. Nearly 700 full colour images and illustrations are included to enhance learning. Key points * Comprehensive guide to clinical medicine * Fully revised, new edition correlates clinical findings with pathological processes * Discusses functions, processes and common disorders in each system of the body * Nearly 700 full colour images and illustrations * Previous edition published in 2008

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Clinical Oral Anatomy: A Comprehensive Review for Dental Practitioners and Researchers 1st ed. 2017 Edition

This superbly illustrated book presents the most current and comprehensive review of oral anatomy for clinicians and researchers alike. In 26 chapters, the reader is taken on a unique anatomical journey, starting with the oral fissure, continuing via the maxilla and mandible to the tongue and floor of the mouth, and concluding with the temporomandibular joint and masticatory muscles. Each chapter offers a detailed description of the relevant anatomical structures and their spatial relationships, provides quantitative morphological assessments, and explains the relevance of the region for clinical dentistry. All dental health care professionals require a sound knowledge of anatomy for the purposes of diagnostics, treatment planning, and therapeutic intervention. A full understanding of the relationship between anatomy and clinical practice is the ultimate objective, and this book will enable the reader to achieve such understanding as the basis for provision of the best possible treatment for each individual patient as well as recognition and comprehension of unexpected clinical findings.

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Enzyme Inhibition in Drug Discovery and Development: The Good and the Bad 1st Edition

The science and applied approaches of enzyme inhibition in drug discovery and development

Offering a unique approach that includes both the pharmacologic and pharmaco-kinetic aspects of enzyme inhibition, Enzyme Inhibition in Drug Discovery and Development examines the scientific concepts and experimental approaches related to enzyme inhibition as applied in drug discovery and drug development.

With chapters written by over fifty leading experts in their fields, Enzyme Inhibition in Drug Discovery and Development fosters a cross-fertilization of pharmacology, drug metabolism, pharmacokinetics, and toxicology by understanding the “good” inhibitions—desirable pharmacological effects—and “bad” inhibitions—drug–drug interactions and toxicity. The book discusses:

  • The drug discovery process, including drug discovery strategy, medicinal chemistry, analytical chemistry, drug metabolism, pharmacokinetics, and safety biomarker assessment
  • The manipulations of drug metabolizing enzymes and transporters as well as the negative consequences, such as drug–drug interactions
  • The inhibition of several major drug target pathways, such as the GPCR pathway, the NFkB pathway, and the ion channel pathway

Through this focused, single-source reference on the fundamentals of drug discovery and development, researchers in drug metabolism and pharmacokinetics (DMPK) will learn and appreciate target biology in drug discovery; discovery biologists and medicinal chemists will also broaden their understanding of DMPK.

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Human Body Odor: Etiology, Treatment, and Related Factors

Strong body odor is a condition for which, until now, there have been few treatment methods. The Japanese authors, encouraged by the willingness of Oriental patients to undergo radical treatment, have developed the subcutaneous tissue shaving method, which eliminates the condition in a very short period of time without ugly scarring. The book Human Body Odor not only introduces the completely new subcutaneous tissue shaving method, it also questions conventional theories on the hair cycle itself and throws a new hypothesis about the process of hair generation and regeneration into the scientific arena. This could even lead in the future to a formula for retarding hair loss! Developed over the past twenty years, the authors’ new surgical method for the radical treatment of bromidrosis represents a landmark in cosmetic surgery and dermatology!

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Palpation Techniques: Surface Anatomy for Physical Therapists 1st Edition

This lavishly illustrated guide to palpation techniques provides readers with
a solid understanding of topographic anatomy using clear, step-by-step
descriptions that teach how to first identify, and then distinguish between, the
various body structures.

Full-color photographs feature models with detailed
drawings of muscles, bones, and tendons sketched directly onto their skin,
indicating exactly where and how to palpate. Complementary color drawings show
the functional significance of each anatomic region.

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Key Topics in Management of the Critically Ill 1st ed. 2016 Edition

This book is designed to assist clinicians who are new to intensive care by providing information on a range of important and novel topics of relevance in the day-to-day management of critically ill patients. Guidance is given on the appropriate response to various emergencies and circumstances, including stroke, acute liver failure, severe burns, extreme pain, and delirium. The role of simulation training in the intensive care unit is discussed, and detailed attention is devoted to the application of modern techniques for the assessment of vital organs in the critical care setting, such as echocardiography and lung ultrasound.  An individual chapter focuses on regional anesthesia in intensive care, and in addition the book addresses subjects and issues that are frequently neglected. Examples include transfer of the critically ill patient, the role of forgotten electrolytes such as magnesium, the use of non-coumarin anticoagulants, and neuropsychological rehabilitation. The book will have broad appeal, including for general intensivists, anesthetists, acute medicine physicians, and medical students attached to acute specialties or preparing for exams in intensive care medicine.

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